Abstract: A mobile ergospirometry system including a portable measurement unit that can be attached to a subject and that incorporates a mouthpiece or mask to collect respiratory gas, a sensor for the volume or amount of gas as well as sensors to determine the CO2/O2 concentration in the respiratory gas, a signal processing unit, and a telemetry module. The system further includes a computer-assisted base station having a telemetry unit to create a wireless connection to the telemetry module. In the system a bidirectional transmission route to the telemetry unit is set up by the telemetry module to transmit data and commands, for which purpose a transmitter and receiver subassembly is provided in each case, so that from the base station it is possible to communicate to the subject online information or requirements for operation of the measurement unit and/or the progress of the test.

Abstract: A method of data management for assessing a patient's autonomic balance, risk of death, and the patient's response to therapy in terms of these assessments is described. This method describes a process by which a set of “raw variables” (RV) are translated into one or more of a new variable, defined as an Mortality Prediction Index, (MPI) that quantifies the patient's cardiovascular reflex control and risk of death. The translated variables are representative of both central and peripheral chemo receptivity, baroreflexes, and peripheral ergo receptors, which, in turn, provide the measurement of sympathovagal, or autonomic, balance. The process of selection and measurement of the MPI, and thus the sympathetic and parasympathetic components of autonomic balance at rest and during dynamic, isotonic exercise and recovery is described. The invention will further define risk of death using a Kaplan-Meier Plot for certain translated variables.

Abstract: A method of data management for assessing a patient's autonomic balance, risk of death, and the patient's response to therapy in terms of these assessments is described. This method describes a process by which a set of “raw variables” (RV) are translated into one or more of a new variable, defined as an Autonomic Balance Index (ABI), that quantifies the patient's cardiovascular reflex control. The translated variables are representative of both central and peripheral chemo receptivity, baroreflexes, and peripheral ergo receptors, which, in turn, provide the measurement of sympathovagal, or autonomic, balance. The process of selection and measurement of the ABI, and thus the sympathetic and parasympathetic components of autonomic balance at rest and during dynamic, isotonic exercise and recovery is described. The invention will further define risk of death using a Kaplan-Meier Plot for certain translated variables.