Patents Assigned to CorTrak Medical, Inc.
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Patent number: 5865787Abstract: An apparatus and method for delivering a drug selectively and locally to internal body tissue with a catheter using electric current/voltage controlled in conjunction with active pacing of cardiac activity.Type: GrantFiled: September 13, 1996Date of Patent: February 2, 1999Assignee: Cortrak Medical, Inc.Inventors: James E. Shapland, Keith R. Hildebrand
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Patent number: 5807306Abstract: A drug delivery apparatus and method for delivering a drug locally to internal body tissue using a catheter device including a polymer matrix containing a drug. The drug is actively transported from the polymer matrix to the internal body tissue using iontophoresis or phonophoresis. In addition, the polymer matrix can be expanded to promote intimate contact with the walls of a passageway or vessel.Type: GrantFiled: August 16, 1994Date of Patent: September 15, 1998Assignee: CorTrak Medical, Inc.Inventors: J. Edward Shapland, Keith R. Hildelbrand, Joel R. Racchini, Jin Shimada, Mark B. Knudson
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Patent number: 5634899Abstract: An apparatus and method for delivering a drug selectively and locally to internal body tissue with a catheter using electric current/voltage controlled in conjunction with active pacing of cardiac activity.Type: GrantFiled: January 4, 1994Date of Patent: June 3, 1997Assignee: CorTrak Medical, Inc.Inventors: James E. Shapland, Keith R. Hildebrand
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Patent number: 5628730Abstract: A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall of the device for direct contact with the passageway wall or body tissue. A further aspect of the present invention involves treating a dilated vessel in the area of a stenotic lesion with a fixative or other drug to render the vessel biologically inert and to form a biological stent or prevent restenosis using specifically selected drugs. A still further aspect of the present invention involves treating a tumor or local or regional tissue mass with antitumor sensitizing agents, biological modifiers, antibiotics or other types of drugs by delivery of the drug to the tumor or tissue area directly or through the passageway wall.Type: GrantFiled: July 18, 1994Date of Patent: May 13, 1997Assignee: Cortrak Medical, Inc.Inventors: James E. Shapland, Mark B. Knudson, Jin Shimada
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Patent number: 5569198Abstract: An apparatus for delivering an agent to a treatment area. The apparatus includes a catheter that has a distal portion and a proximal portion. The catheter defines a lumen. A pressure regulator is in fluid communication with the lumen. A selectively inflatable member is also in fluid communication with the lumen, and is formed from a membrane. The membrane has first and second portions. The first portion defines pores sized from about 0.05.mu. to about 1.mu. and has a pore density from about 10.sup.6 pores/cm.sup.2 to about 10.sup.9 pores/cm.sup.2. The flux rate is from about 0.001 ml/(min.multidot.cm.sup.2 .multidot.atm) to about 0.4 ml/(min.multidot.cm.sup.2 .multidot.atm). The second portion is substantially impermeable.Type: GrantFiled: January 23, 1995Date of Patent: October 29, 1996Assignee: CorTrak Medical Inc.Inventor: Joel R. Racchini
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Patent number: 5499971Abstract: A drug delivery apparatus and method for iontophoretically delivering a drug locally to internal body tissue. The iontophoretic delivery apparatus and method include a current source producing a net flow of current in a desired direction with high frequency waveforms which enhance delivery and minimize side effects typically associated with iontophoresis.The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is iontophoretically transported across a drug transport wall of the device for direct contact with the passageway wall or body tissue. A further aspect of the present invention involves treating a dilated vessel in the area of a stenotic lesion with a fixative or other drug to render the vessel biologically inert and to form a biological stent or prevent restenosis using specifically selected drugs.Type: GrantFiled: December 14, 1993Date of Patent: March 19, 1996Assignee: Cortrak Medical, Inc.Inventors: James E. Shapland, Keith R. Hildebrandt, Mark B. Knudson
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Patent number: 5498238Abstract: A method of simultaneous angioplasty and drug delivery to a localized portion of coronary or peripheral arteries or any other type of body passage that has a stricture. The invention contemplates positioning a drug delivery device in a body passageway and then selectively introducing a selected drug so that the device is expanded in order to dilate the passage and then simultaneously causing the drug to be transported across a drug transport wall of the device for direct contact with the passageway wall. A more specific aspect of the present invention involves treating a dilated vessel in the area of a stenotic lesion with a fixative or other drug to render the vessel biologically inert and to form a biological stent or prevent restenosis using specifically selected drugs.Type: GrantFiled: August 27, 1993Date of Patent: March 12, 1996Assignee: CorTrak Medical, Inc.Inventors: James E. Shapland, Mark B. Knudson, Jin Shimada, Joel R. Racchini
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Patent number: 5458568Abstract: A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively wetting a membrane within the device, making the membrane permeable and allowing transport of a drug across the membrane and into the passageway wall or body tissue.Type: GrantFiled: September 17, 1993Date of Patent: October 17, 1995Assignee: CorTrak Medical, Inc.Inventors: Joel R. Racchini, James E. Shapland, Mark B. Knudson, Jin Shimada, Keith R. Hildebrand
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Patent number: 5419763Abstract: A method and apparatus for the treatment of a prostate gland which isolates the prostatic urethra from the membranous urethra and the bladder so that fluid may be transported into the prostatic ducts without compromising the openings to the prostatic ducts. One preferred embodiment incorporates balloons located at either end of the prostatic urethra to isolate the same.Type: GrantFiled: January 4, 1994Date of Patent: May 30, 1995Assignee: CorTrak Medical, Inc.Inventor: Keith R. Hildebrand
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Patent number: 5286254Abstract: A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall of the device for direct contact with the passageway wall or body tissue. A further aspect of the present invention involves treating a dilated vessel in the area of a stenotic lesion with a fixative or other drug to render the vessel biologically inert and to form a biological stent or prevent restenosis using specifically selected drugs. A still further aspect of the present invention involves treating a tumor or local or regional tissue mass with antitumor sensitizing agents, biological modifiers, antibiotics or other types of drugs by delivery of the drug to the tumor or tissue area directly or through the passageway wall.Type: GrantFiled: August 28, 1992Date of Patent: February 15, 1994Assignee: CorTrak Medical, Inc.Inventors: James E. Shapland, Mark B. Knudson, Jin Shimada
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Patent number: 5282785Abstract: A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall of the device for direct contact with the passageway wall or body tissue. A further aspect of the present invention involves treating a dilated vessel in the area of a stenotic lesion with a fixative or other drug to render the vessel biologically inert and to form a biological stent or prevent restenosis using specifically selected drugs. A still further aspect of the present invention involves treating a tumor or local or regional tissue mass with antitumor sensitizing agents, biological modifiers, antibiotics or other types of drugs by delivery of the drug to the tumor or tissue area directly or through the passageway wall.Type: GrantFiled: October 5, 1992Date of Patent: February 1, 1994Assignee: CorTrak Medical, Inc.Inventors: James E. Shapland, Mark B. Knudson, Jin Shimada, Keith R. Hildebrand