Patents Assigned to Corus Pharma
  • Substituted Phenylphosphates as Mutual Prodrugs of Steroids and ß-Agonists for the Treatment of Title Pulmonary Inflammation and Bronchoconstriction
    Publication number: 20100209508
    Abstract: A mutual prodrug of a corticosteroid and a substituted phenylphosphate (?-agonist derivative) for formulation for delivery by aerosolization to inhibit pulmonary inflammation and bronchoconstriction is described. The mutual prodrug is preferably formulated in a small volume solution (10-500 ?L) dissolved in a quarter normal saline having pH between 5.0 and 7.0 for the treatment of respiratory tract inflammation and bronchoconstriction by an aerosol having mass median average diameter predominantly between 1 to 5?, produced by nebulization or by dry powder inhaler.
    Type: Application
    Filed: June 12, 2006
    Publication date: August 19, 2010
    Applicant: CORUS PHARMA, INC.
    Inventors: William Baker, Marcin Stasiak, Charles Bruce Girton
  • Aztreonam L-lysine and methods for the preparation and analysis thereof
    Patent number: 7358093
    Abstract: The present invention relates to the L-lysine salt of aztreonam and methods for making the L-lysine salt of aztreonam.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: April 15, 2008
    Assignee: Corus Pharma, Inc.
    Inventors: Viktor Gyollai, Csaba Szabo, Claude Singer, Istvan Bodi
  • Aztreonam L-lysine and methods for the preparation thereof
    Patent number: 7262293
    Abstract: The present invention relates to the L-lysine salt of aztreonam and methods for making the L-lysine salt of aztreonam.
    Type: Grant
    Filed: July 1, 2004
    Date of Patent: August 28, 2007
    Assignee: Corus Pharma
    Inventors: Viktor Gyollai, Csaba Szabo, Claude Singer, Istvan Bodi
  • Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
    Patent number: 7214364
    Abstract: A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter species, Serratia marcescens as well as those caused by Burkholderia cepacia, Stenotrophomonas maltophilia, Alcaligenes xylosoxidans, and multidrug resistant Pseudomonas aeruginosa, using a concentrated formulation of aztreonam lysinate delivered as an aerosol or dry powder formulation.
    Type: Grant
    Filed: July 3, 2003
    Date of Patent: May 8, 2007
    Assignee: Corus Pharma, Inc.
    Inventor: Alan Bruce Montgomery
  • Inhalable aztreonam aerosol for treatment and prevention of pulmonary bacterial infections
    Patent number: 7208141
    Abstract: A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter species, Serratia marcescens as well as those caused by Burkholderia cepacia, Stenotrophomonas maltophilia, Alcaligenes xylosoxidans, and multidrug resistant Pseudomonas aeruginosa, using a concentrated formulation of aztreonam, or a pharmaceutically acceptable salt thereof, delivered as an aerosol or dry powder formulation.
    Type: Grant
    Filed: September 4, 2003
    Date of Patent: April 24, 2007
    Assignee: Corus Pharma, Inc.
    Inventor: Alan Bruce Montgomery
  • Process for manufacturing bulk solutions and a lyophilized pure ?-aztreonam lysinate
    Patent number: 7138419
    Abstract: A process for manufacturing bulk solutions and lyophilized pure ?-aztreonam lysinate for large scale production of an inhalable aztreonam is disclosed, as is a pure ?-aztreonam lysinate for inhalation. A dry powder or lyophilized pure ?-aztreonam lysinate composition for inhalation is also disclosed.
    Type: Grant
    Filed: June 30, 2004
    Date of Patent: November 21, 2006
    Assignee: Corus Pharma, Inc.
    Inventors: Alan Bruce Montgomery, Iain Duncan, Peter Carbonaro