Patents Assigned to Cosmax NBT, Inc.
  • Publication number: 20240016876
    Abstract: The present invention relates to a composition for hangover relief, comprising a noni fruit extract or a fraction thereof, and more specifically provides a noni fruit extract or a fraction thereof, which is prepared using a certain concentration of ethanol as an extraction solvent, to contain a large amount of polysaccharides having excellent hangover relieving functionality and an average molecular weight of 8 kDa to 10 kDa.
    Type: Application
    Filed: November 17, 2021
    Publication date: January 18, 2024
    Applicants: Cosmax NBT, Inc., Cosmax NS, Inc.
    Inventors: Ji Hwan JANG, Min Son KWEON, Su Young CHOI
  • Publication number: 20230270811
    Abstract: The present invention relates to a composition for the prevention or treatment of respiratory diseases containing an Agastache rugosa and licorice extract as an active ingredient, and more specifically, the present invention relates to a composition for the prevention or treatment of respiratory diseases caused by fine dust containing an extract, in which Agastache rugosa and licorice are mixed at a weight ratio of 1:1 to 6:1, as an active ingredient. The Agastache rugosa and licorice extract of the present invention has the efficacies of reducing cough through inhibition of TRPV1 activity, reducing lung inflammation through inhibition of CXCR1 and CXCR2 activities and GR-1+CD11b+ cell ratio reduction, and suppressing sputum production through inhibition of MUC5AC activity.
    Type: Application
    Filed: September 23, 2022
    Publication date: August 31, 2023
    Applicants: Cosmax NBT, Inc., Cosmax NS, Inc.
    Inventors: Jeong Ho GEUM, Hye Rim KIM, Jin Hak KIM, Su Young CHOI
  • Publication number: 20230210932
    Abstract: The present invention relates to a composition for the prevention or treatment of respiratory diseases containing an Agastacherugosa and licorice extract as an active ingredient, and more specifically, the present invention relates to a composition for the prevention or treatment of respiratory diseases caused by fine dust containing an extract, in which Agastacherugosa and licorice are mixed at a weight ratio of 1:1 to 6:1, as an active ingredient. The Agastacherugosa and licorice extract of the present invention has the efficacies of reducing cough through inhibition of TRPV1 activity, reducing lung inflammation through inhibition of CXCR1 and CXCR2 activities and GR-1+CD11b+ cell ratio reduction, and suppressing sputum production through inhibition of MUC5AC activity.
    Type: Application
    Filed: May 21, 2020
    Publication date: July 6, 2023
    Applicants: Cosmax NBT, Inc., Cosmax NS, Inc.
    Inventors: Jeong Ho GEUM, Hye Rim KIM, Jin Hak KIM, Su Young CHOI
  • Patent number: 11628195
    Abstract: The present invention relates to a method of preparing a noni fruit extract containing a high iridoid content or a fraction thereof, a method of preparing a noni fruit extract containing a high content of an immune-enhancing active substance or a fraction thereof, and a use of a noni fruit extract or a fraction thereof, and more specifically, the present invention provides a method of preparing a noni fruit extract containing a high iridoid content or a fraction thereof, including preparing a noni fruit extract by using ethanol in a specific concentration range as an extraction solvent, a method of preparing a noni fruit extract containing a high content of an immune-enhancing active substance or a fraction thereof, a pharmaceutical composition for enhancing immunity including the extract or a fraction thereof, a health functional food composition including the same constitution, a method of enhancing immunity using the extract or a fraction thereof, and a use of the extract or a fraction thereof in preparati
    Type: Grant
    Filed: June 2, 2020
    Date of Patent: April 18, 2023
    Assignees: Cosmax NBT, Inc., Cosmax NS, Inc.
    Inventors: Ji Hwan Jang, Jin Hak Kim, Bo Ra Jin, Su Young Choi, Hyun Ji Kim
  • Publication number: 20230055713
    Abstract: A composition for strengthening a skin barrier or moisturizing skin is provided. The composition includes tilianin. The composition may be a food, a health functional food composition, a quasi-drug composition and/or a composition for external use on the skin. The composition increases the contents of moisture and hyaluronic acid in the skin and exhibits an upregulating effect on HAS. A method for strengthening a skin barrier or enhancing skin moisture using tilianin, and provides a use of tilianin in the preparation of food or medicine for strengthening a skin barrier or enhancing skin moisture are also provided.
    Type: Application
    Filed: January 12, 2022
    Publication date: February 23, 2023
    Applicants: COSMAX NBT, INC., COSMAX NS, INC.
    Inventors: Jin Hee YOO, Su Young CHOI, Mann-Seok YUN, Won Il YUN
  • Publication number: 20230000758
    Abstract: Provided are a method for preventing or treating photoaging of skin, including: administering a composition comprising an effective amount of an extract of Agastache rugosa O Kuntze to a subject in need thereof. The composition decreases expression of matrix metalloproteinases (MMPs) induced by ultraviolet B (UVB) irradiation; decreases expression of mitogen-activated protein kinase (MAPK)/activator protein-1 (AP-1) signaling; improves collagen synthesis; decreases skin inflammation induced by NF-?B; and decreases oxidative stress induced by UVB irradiation.
    Type: Application
    Filed: June 25, 2021
    Publication date: January 5, 2023
    Applicants: COSMAX NBT, INC., COSMAX NS, INC.
    Inventors: Jin Hee YOO, Su Young CHOI, Won Il YUN
  • Patent number: 11382336
    Abstract: The present disclosure relates to emulsified oil composition including an oil containing a polyunsaturated fatty acid which is applicable to food, a rosemary extract, and a non-ionic surfactant, wherein the product quality of the food using the oil containing the polyunsaturated fatty acid is maintained during the processing and storage of the food, by preventing the oxidation of the oil containing the polyunsaturated fatty acid to suppress the production of a rancid flavor and an off-flavor.
    Type: Grant
    Filed: September 3, 2019
    Date of Patent: July 12, 2022
    Assignee: COSMAX NBT, INC.
    Inventors: Jin Woo Park, Hye Jin Kim, Hye Young Kim, Jee Ho Park, Gi Tae Choe
  • Publication number: 20220080018
    Abstract: The present invention relates to a method of preparing a noni fruit extract containing a high iridoid content or a fraction thereof, a method of preparing a noni fruit extract containing a high content of an immune-enhancing active substance or a fraction thereof, and a use of a noni fruit extract or a fraction thereof, and more specifically, the present invention provides a method of preparing a noni fruit extract containing a high iridoid content or a fraction thereof, including preparing a noni fruit extract by using ethanol in a specific concentration range as an extraction solvent, a method of preparing a noni fruit extract containing a high content of an immune-enhancing active substance or a fraction thereof, a pharmaceutical composition for enhancing immunity including the extract or a fraction thereof, a health functional food composition including the same constitution, a method of enhancing immunity using the extract or a fraction thereof, and a use of the extract or a fraction thereof in preparati
    Type: Application
    Filed: June 2, 2020
    Publication date: March 17, 2022
    Applicants: Cosmax NBT, Inc., Cosmax NS, Inc.
    Inventors: Ji Hwan JANG, Jin Hak KIM, Bo Ra JIN, Su Young CHOI, Hyun Ji KIM
  • Publication number: 20210401916
    Abstract: The present invention relates to a composition for preventing or treating a muscle disorder, which includes a Chrysanthemum extract or 3,5-dicaffeoylquinic acid as an active ingredient, and specifically, it may be used to reduce mRNA expression of atrogin-1 and MuRF1, which are main biomarkers involved in muscle protein degradation and increase mRNA expression of the mTOR protein, which is a main biomarker involved in muscle protein formation, and myogenin and MyoD, which are biomarkers related to muscle differentiation, thereby reducing muscle loss, and thus the Chrysanthemum extract or 3,5-dicaffeoylquinic acid can be used in prevention and treatment of a muscle disorder, or improvement in muscle function. In addition, the Chrysanthemum extract or 3,5-dicaffeoylquinic acid increases the activity of SIRT1 and PGC-1?, which are the main biomarkers involved in exercise performance, thereby excellently enhancing exercise performance.
    Type: Application
    Filed: September 20, 2021
    Publication date: December 30, 2021
    Applicants: Industry-Academic Cooperation Foundation, Yonsei University, Cosmax NBT, Inc., Cosmax NS, Inc.
    Inventors: Jae Kwan HWANG, Jun Gon YUN, Mi Bo KIM, Chang Hee KIM, Joon Hyung LEE, Do Wan KWON, Su Young CHOI, Jin Hak KIM, Ji Hwan JANG, Jeong Ho GEUM, Min Son KWEON
  • Patent number: 11160840
    Abstract: The present invention relates to a composition for preventing or treating a muscle disorder, which includes a chrysanthemum extract or 3,5-dicaffeoylquinic acid as an active ingredient, and specifically, it may be used to reduce mRNA expression of atrogin-1 and MuRF1, which are main biomarkers involved in muscle protein degradation and increase mRNA expression of the mTOR protein, which is a main biomarker involved in muscle protein formation, and myogenin and MyoD, which are biomarkers related to muscle differentiation, thereby reducing muscle loss, and thus the chrysanthemum extract or 3,5-dicaffeoylquinic acid can be used in prevention and treatment of a muscle disorder, or improvement in muscle function. In addition, the chrysanthemum extract or 3,5-dicaffeoylquinic acid increases the activity of SIRT1 and PGC-1?, which are the main biomarkers involved in exercise performance, thereby excellently enhancing exercise performance.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: November 2, 2021
    Assignees: Industry-Academic Cooperation Foundation, Yonsei University, Cosmax NBT, Inc., Cosmax NS, Inc.
    Inventors: Jae Kwan Hwang, Jun Gon Yun, Mi Bo Kim, Chang Hee Kim, Joon Hyung Lee, Do Wan Kwon, Su Young Choi, Jin Hak Kim, Ji Hwan Jang, Jeong Ho Geum, Min Son Kweon
  • Patent number: 10722548
    Abstract: The present invention relates to a method of preparing a lyophilizate of a Taheebo alcohol extract, including: (a) extracting Taheebo with an alcohol and concentrating an extract; and (b) lyophilizing the alcohol-extracted and concentrated Taheebo, and a composition for the treatment, prevention or amelioration of an inflammatory disease including a lyophilizate of a Taheebo alcohol extract prepared therefrom.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: July 28, 2020
    Assignees: COSMAX NBT, INC., COSMAX NS, INC.
    Inventors: Kwang Soo Baek, Jin Hak Kim, Su Young Choi, Young Min Park, Jae Seok Shim, Sang Woo Kim, Mann Seok Yoon, Yoon Jong Lee
  • Patent number: 10682384
    Abstract: The present invention relates to a composition comprising a natural complex extract. It is confirmed that the composition has synergistic effects on antioxidant activity, immune enhancement, whitening, anti-wrinkle and collagenase inhibition with low cytotoxicity, and therefore, the composition is suitable for uses of antioxidation, immune, whitening and skin anti-wrinkle.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: June 16, 2020
    Assignees: COSMAX NS, INC., COSMAX NBT, INC.
    Inventors: Jin Hak Kim, Kwang Soo Baek, Yong Jun Jo, Hyeon Yeong Ahn, Young Min Park, Hyun Ji Kim, Jae Seok Shim, Su Young Choi, Jin Woo Lee, Sang Woo Kim, Mann-Seok Yoon, Jin Hyouk Kwon
  • Publication number: 20200009208
    Abstract: The present invention relates to a composition for preventing or treating a muscle disorder, which includes a chrysanthemum extract or 3,5-dicaffeoylquinic acid as an active ingredient, and specifically, it may be used to reduce mRNA expression of atrogin-1 and MuRF1, which are main biomarkers involved in muscle protein degradation and increase mRNA expression of the mTOR protein, which is a main biomarker involved in muscle protein formation, and myogenin and MyoD, which are biomarkers related to muscle differentiation, thereby reducing muscle loss, and thus the chrysanthemum extract or 3,5-dicaffeoylquinic acid can be used in prevention and treatment of a muscle disorder, or improvement in muscle function. In addition, the chrysanthemum extract or 3,5-dicaffeoylquinic acid increases the activity of SIRT1 and PGC-1?, which are the main biomarkers involved in exercise performance, thereby excellently enhancing exercise performance.
    Type: Application
    Filed: November 30, 2017
    Publication date: January 9, 2020
    Applicants: Industry-Academic Cooperation Foundation, Yonsei University, Cosmax NBT, Inc., Cosmax NS, Inc.
    Inventors: Jae Kwan HWANG, Jun Gon YUN, Mi Bo KIM, Chang Hee KIM, Joon Hyung LEE, Do Wan KWON, Su Young CHOI, Jin Hak KIM, Ji Hwan JANG, Jeong Ho GEUM, Min Son KWEON