Abstract: The present invention relates to a method of preparing a lyophilizate of a Taheebo alcohol extract, including: (a) extracting Taheebo with an alcohol and concentrating an extract; and (b) lyophilizing the alcohol-extracted and concentrated Taheebo, and a composition for the treatment, prevention or amelioration of an inflammatory disease including a lyophilizate of a Taheebo alcohol extract prepared therefrom.
July 14, 2017
Date of Patent:
July 28, 2020
COSMAX NBT, INC., COSMAX NS, INC.
Kwang Soo Baek, Jin Hak Kim, Su Young Choi, Young Min Park, Jae Seok Shim, Sang Woo Kim, Mann Seok Yoon, Yoon Jong Lee
Abstract: The present invention relates to a composition comprising a natural complex extract. It is confirmed that the composition has synergistic effects on antioxidant activity, immune enhancement, whitening, anti-wrinkle and collagenase inhibition with low cytotoxicity, and therefore, the composition is suitable for uses of antioxidation, immune, whitening and skin anti-wrinkle.
January 10, 2018
Date of Patent:
June 16, 2020
COSMAX NS, INC., COSMAX NBT, INC.
Jin Hak Kim, Kwang Soo Baek, Yong Jun Jo, Hyeon Yeong Ahn, Young Min Park, Hyun Ji Kim, Jae Seok Shim, Su Young Choi, Jin Woo Lee, Sang Woo Kim, Mann-Seok Yoon, Jin Hyouk Kwon
Abstract: The present invention relates to a composition for preventing or treating a muscle disorder, which includes a chrysanthemum extract or 3,5-dicaffeoylquinic acid as an active ingredient, and specifically, it may be used to reduce mRNA expression of atrogin-1 and MuRF1, which are main biomarkers involved in muscle protein degradation and increase mRNA expression of the mTOR protein, which is a main biomarker involved in muscle protein formation, and myogenin and MyoD, which are biomarkers related to muscle differentiation, thereby reducing muscle loss, and thus the chrysanthemum extract or 3,5-dicaffeoylquinic acid can be used in prevention and treatment of a muscle disorder, or improvement in muscle function. In addition, the chrysanthemum extract or 3,5-dicaffeoylquinic acid increases the activity of SIRT1 and PGC-1?, which are the main biomarkers involved in exercise performance, thereby excellently enhancing exercise performance.