Abstract: The present invention relates to 1,2,3-triazole containing artemisinin compounds and process for preparation thereof. Described herein is the synthesis, bioassay results and usefulness of the artemisinin derived compounds resulting from 1,3-dipolar cycloaddition reaction of artemisinin derived azide or alkyne with aliphatic or aromatic diazides. These 1,2,3-triazole containing artemisinin derived compounds embodied in this document are found to be active against various cancer cell-lines.
Type:
Grant
Filed:
February 14, 2012
Date of Patent:
April 14, 2015
Assignee:
Councel of Scientific & Industrial Research
Inventors:
Bishwajit Saikia, Nabin C. Barua, Partha P. Saikia, Abhishek Goswami, Paruchuri G. Rao, Ajit K. Saxena, Nitasha Suri