Abstract: The present invention discloses a highly conducting polyethylenedioxythiphene (PEDOT) flexible paper with a very low sheet resistance and high conductivity and process for preparation thereof, by inducing the polymerization at the interface of two immiscible liquids on a cellulose paper to trigger PEDOT growth along the fibers of the cellulose paper. The present invention discloses the use of the said conducting paper for the preparation of flexible supercapacitor and for the preparation of counter electrode in Dye Sensitized Solar Cell (DSSC).
Type:
Grant
Filed:
December 23, 2015
Date of Patent:
April 23, 2019
Assignee:
Council of Scientific & Industrial Research
Abstract: The present invention relates to a novel process for the preparation of a linear monomer alkyl lactyl lactate by a simple esterification reaction of acid with ester in presence of suitable catalysts or reagents. The present invention further relates to a process for the preparation of poly acid from alkyl lactyl lactate by using suitable catalyst.
Type:
Grant
Filed:
January 29, 2016
Date of Patent:
April 23, 2019
Assignee:
Council of Scientific and Industrial Research
Abstract: The present invention relates to a formulation of Spinacea oleracea useful for the prevention or treatment of osteo-health related disorders. The present invention relates to the field of pharmaceutical formulation that provides extract, fractions, pure compound isolated from natural sources and formulation thereof useful for the prevention and treatment of various medical indications. Further, this invention relates to conditions associated with estrogen dependent or independent diseases (primary/secondary osteoporosis) or syndromes or disorders preferably relating to cartilage such as osteoarthritis caused in humans and animals. Furthermore, this invention relates to achievement of peak bone mass during skeletal growth and health in humans and animals.
Type:
Grant
Filed:
June 28, 2017
Date of Patent:
April 23, 2019
Assignee:
Council of Scientific & Industrial Research
Abstract: The present invention relates to the cationic lipid cordiaroimide hybrid compounds of formula I. The present invention provides a process for preparation of these compounds is also being elaborated. The compounds described provides anticancerous activity against cell lines including PC-3 (prostate cancer), HepG2 (liver cancer), MCF-7 (breast cancer) and NIH-1/3T3 (non cancer cells. The compound was also capable of inducing caspase-3 mediated apoptosis in HepG2 cells by arresting the cell cycle in the G1 phase. Furthermore, the compound exhibited DNA ligase I inhibition. The present class of cationic lipid cordiarimide hybrids is likely to find specific use in developing novel targeted therapies for liver and prostate cancers.
Type:
Grant
Filed:
June 10, 2015
Date of Patent:
April 23, 2019
Assignee:
Council of Scientific & Industrial Research
Abstract: The present invention discloses polymeric ionic liquid (PIL) composition comprising a polymer selected from PBI or ABPBI and their derivatives or analogues covalently attached to fluorescence moiety selected from poly aromatic hydrocarbons, preferably pyrene or anthracene. Further, the invention discloses a process for preparing said composition with enhanced fluorescence and stability. Also, disclosed herein is the use of said fluorescent PIL in detection of explosives, as membranes for gas permeation and as chemo sensors.
Type:
Grant
Filed:
February 27, 2015
Date of Patent:
April 23, 2019
Assignee:
Council of Scientific & Industrial Research
Abstract: The present invention relates to a short enantioselective synthesis of 1-amino aryl tetraline compounds of Formula 1 via nucleophilic enamine catalysis using organocatalyst such as proline. wherein R1 and R2 represent independent of each other hydrogen, (un)substituted or substituted amine; R3 and R4 represent independent of each other hydrogen or halogen.
Type:
Grant
Filed:
June 22, 2015
Date of Patent:
April 23, 2019
Assignee:
Council of Scientific & Industrial Research
Abstract: The conventional radiation shielding materials are made using lead, barite and hematite ore which are either toxic, costly and are non-replinshable possessing limited functionality. In view of above, we develop a novel process for making advanced non-toxic Red Mud based functional radiation shielding materials utilizing appropriate novel matrixes like Advanced geopolymer, geopolymeric-polymeric matrix, putty, cement and phosphatic based matrix and are also compatible with conventional matrixes. The appropriate physico-chemical consolidation and or densification of red mud using advanced or conventional matrix helps in obtaining functional radiation shielding material by simultaneous and synergistic chemical reactions among various mineralogical and chemical compounds of red mud with complementary various chemical compounds present in citrus fruit peel waste especially citric acid to form nano gel material to obtain the fine “tailored shielding powder”.
Type:
Grant
Filed:
October 27, 2017
Date of Patent:
April 16, 2019
Assignee:
Council of Scientific and Industrial Research
Inventors:
Sudhir Sitaram Amritphale, Sarika Verma, Satyabrata Das
Abstract: The present invention relates to a process for the preparation of Calcium Silicate Hydrate anion exchange membrane (cement paste) with an ionic conductivity of the order of 10?3 S/cm. The membrane can be formulated by mixing Ordinary Portland Cement (OPC) and water with the cement to water ratio of 1:0.45. After initial setting time, the membrane undergoes curing in 7% calcium chloride solution and the Cl? ions in the membrane is converted to OH? form by immersing into saturated Ca(OH)2 solution with pH 14 and it has been washed to remove the excess alkali. This membrane has high mechanical strength (Ultimate Tensile Strength: 6.3 MPa) and does not deteriorate even at high temperature (up to 450° C.) and alkaline atmosphere (pH 11.5-14). Also disclosed is a method of producing in-situ formation of membrane electrode assembly. This invention encompasses a process for producing and using the membrane in water electrolysis and fuel cell.
Type:
Grant
Filed:
January 30, 2017
Date of Patent:
April 16, 2019
Assignee:
Council of Scientific & Industrial Research
Inventors:
Jayashree Swaminathan, Subbiah Ravichandran, Donald Jonas Davidson, Ganapathy Sozhan, Subramanyan Vasudevan, Singaram Vengatesan, Srinivasan Muralidharan
Abstract: This invention relates to the development of processes for the preparation of functionalized castor oil derivatives namely ring-opened glyceryl ricinoleates, epoxy alkyl ricinoleates and ring-opened alkyl ricinoleates with tailorable properties from epoxidized castor oil as raw material using heterogeneous acid and base catalysts. More particularly, the invention employs two reaction chemistries namely ring-opening and transesterification using Amberlyst 15 as solid acid catalyst for the former and oxides derived from CaAl layered double hydroxide (CaAl-LDH) as solid base catalyst for the latter and combinations thereof. Furthermore, both the catalysts are reusable and the products are easily separable after the reaction by simple physical processes.
Type:
Grant
Filed:
August 6, 2015
Date of Patent:
April 16, 2019
Assignee:
Council of Scientific and Industrial Research
Abstract: The present invention discloses anti-malarial compound of formula (I) Formula (I) wherein, X is selected from O or NH; R1, R2, R3, R4 and R5 is selected from H or OMe or CH3, —CH2—O—CH2— or —CH?CH—CH?CH—; Y is selected from O or NH and R6, R7 is selected from the following compounds: or pharmaceutically acceptable salts thereof, process for preparation and a pharmaceutical composition containing the same.
Type:
Application
Filed:
October 21, 2015
Publication date:
April 11, 2019
Applicants:
Council of Scientific & Industrial Research, Council of Scientific & Industrial Research
Abstract: A 1,2,3 triazole-thiazole compound of formula (I) or pharmaceutically acceptable salt thereof, process for its preparation, its pharmaceutical composition and method for the treatment for stalling vitiligo spread or provide prophylactic benefit to individuals with vitiligo predisposition.
Type:
Grant
Filed:
December 20, 2016
Date of Patent:
April 2, 2019
Assignee:
Council of Scientific & Industrial Research
Abstract: The present invention relates to an electromagnetic acoustic transducer excitation system comprising a tone burst generator, the tone burst generator comprising: an oscillator device configured to produce a radio frequency signal; an analog switch configured to produce an output based on the radio frequency signal produced by the oscillator device and a control signal; a pre-amplifier configured to amplify the output of the analog switch and produce a tone burst output signal; and a control module configured to produce the control signal for providing to the analog switch.
Type:
Grant
Filed:
December 1, 2017
Date of Patent:
April 2, 2019
Assignee:
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
Abstract: This present invention relates to (Z)-3,4,5-Trimethoxystyrylbenzenesulfonamides of general formula A. The invention also provides the synthesis of (Z)-3,4,5-trimethoxystyrylbenzenesulfonamides useful as potential antitumor agents against human cancer cell lines and a process for the preparation thereof.
Type:
Grant
Filed:
October 27, 2015
Date of Patent:
April 2, 2019
Assignee:
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
Abstract: The patent discloses bisphenol monomers of formula I with pendant maleimide group connected via alkylene spacer and preparation thereof. Also, it discloses polymers based on bisphenol monomers containing pendant clickable maleimide group. Further, it provides a process for the preparation of polymers possessing pendant clickable maleimide groups based on bisphenols containing pendant maleimide group. Formula (I) wherein, x is an integer selected from 0 to 10.
Type:
Grant
Filed:
January 15, 2016
Date of Patent:
March 26, 2019
Assignee:
Council of Scientific & Industrial Research
Abstract: The present invention relates to a novel analogs of benzenecarbothioccyclopenta[c]pyrrole-1,3-dione of formula (I) useful for treating various viral infections and process for synthesis thereof. The present invention provides a novel process for synthesis of nitrosporeusines A(1) and B(2). More particularly, the present invention provides a synthetic route for synthesis of nitrosporeusines A(1) and B(2). Said process is simple, industrially scalable, cost effective and eco-friendly.
Type:
Grant
Filed:
October 1, 2015
Date of Patent:
March 26, 2019
Assignee:
Council of Scientific & Industrial Research
Inventors:
Dumbala S. Reddy, Satish C. Philkhana, Gorakhnath R. Jachak, Vidya B. Gunjal
Abstract: The invention discloses a process for hydrogenation (alkenes, carbonyl compounds and aromatics) and hydrodeoxygenation (methoxy phenols) of organic molecules using hydrous ruthenium oxide (HRO) and its supported form as a recyclable heterogeneous catalyst in aqueous medium with good yield of desired products (70-100%) under mild reaction conditions.
Type:
Application
Filed:
October 7, 2016
Publication date:
March 21, 2019
Applicant:
Council of Scientific & Industrial Research
Abstract: The present invention relates to highly biocompatible or nontoxic PVP (poly(n-vinyl-2-pyrrolidone) coated silver prussian blue nanoparticles (SPB-NPS: Ag3[Fe(CN)6] where PVP acts as stabilizing or capping agent. The as-synthesized nanoparticles (SPB-NPs) have been thoroughly characterized by several analytical tools. The SPB-NPs are highly stable for more than two weeks towards different physiological buffers or solutions with different pH (pH=6, ?7.4 & ?8). These nanoparticles (SPB-NPs) exhibit biocompatibility towards various normal cells (HUVEC, CHO, & ECV304) but show significant inhibition of proliferation of different cancer cells in vitro and tumor growth in C57/BL6/J mice model (aggressive murine melanoma cancer model: B16F10). Additionally, the SPB-NPs show excellent antibacterial activity towards gram-negative (E. coli) and gram-positive (B. subtilis) bacteria.
Type:
Grant
Filed:
February 22, 2016
Date of Patent:
March 19, 2019
Assignee:
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
Abstract: An automated method for remote computing of molecular docking and dynamics from one or more jobs in a network of plurality of users. The invention employs a system to execute the method comprising at least one user device, a remote computing server and a remote database. The job defining action tags are received and scanned by the remote server. A semantic analysis is performed on the jobs to distinguish between customized and non-customized tasks. A data analysis of the jobs is packaged in a compressed format. The user is continually updated of the job status. A public link is generated and sent to the user to download the results. The link is disabled after the downloading of the results to ensure the security of the data. The method avoids any duplication of jobs and can be performed even when the user is offline.
Type:
Application
Filed:
October 28, 2016
Publication date:
March 14, 2019
Applicant:
COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
Abstract: Liposomal compositions comprising of liposomes of guanidinylated cationic amphiphiles as the main lipid and cholesterol/1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)/aminopropyl polyethyleneglycol carbamyl-distearoylphosphatidyl-ethanolamine (DSPE-peg-NH2) as co-lipids are described. These liposomal compositions containing encapsulated or electrostatically complexed therapeutic small interfering RNAs (siRNAs) against Cdc20, a key cell cycle regulator, inhibit solid tumor growth and melanoma tumor growth on lung in C57BL/6J mice.
Type:
Grant
Filed:
January 28, 2013
Date of Patent:
March 12, 2019
Assignee:
COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
Abstract: The patent discloses novel quinoline derivatives of formula (I), (Formula should be inserted here) and process for preparing the same. The compounds of formula (I) can be further used for the synthesis of Inhibitors like Kinase Tyrosine Inhibitors.
Type:
Grant
Filed:
February 3, 2016
Date of Patent:
March 12, 2019
Assignee:
Council of Scientific and Industrial Research