Patents Assigned to Council Scientific & Industrial Research
  • Patent number: 6413553
    Abstract: A pharmaceutical formulation is provided which is useful as a leukotrine synthesis and IL4 inhibitor and as a Th1 immunomodulator. The formulation comprises an effective amount of a combination of extracts and lyophilized extracts of Piper betel and Murrya koeniggi. The formulation can be formulated with pharmaceutically acceptable carriers. The formulation can be used in a method of treating humans for respiratory conditions.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: July 2, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Santu Bandyopadhyay, Keshab Chandra Roy, Mitali Roy, Bikash Chandra Pal, Ranjan Bhadra, Krishna Das, Samir Bhattacharaya
  • Publication number: 20020082428
    Abstract: The invention pertains to a process for the preparation of a novel UV absorbing diol of the general formula: 1
    Type: Application
    Filed: December 27, 2000
    Publication date: June 27, 2002
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Paragkumar Nathalal Thanki, Raj Pal Singh
  • Publication number: 20020082432
    Abstract: The present invention discloses novel podophyllotoxin dimers having structural formula I 1
    Type: Application
    Filed: December 22, 2000
    Publication date: June 27, 2002
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Ahmed Kamal, Laxman Eltepu, Arifuddin Mohammed, Gollapalli Bhasker Ramesh Khanna
  • Patent number: 6410059
    Abstract: A pharmaceutical composition comprising an antibiotic and cow urine distillate in an amount effective to enhance antimicrobial effect of the antibiotic is disclosed. The antibiotic can be an antifungal agent. The antibiotic can be a quinolone or a fluoroquinolone. The antifungal agent can be azoles, clotrimazole, mystatin or amphotericin.
    Type: Grant
    Filed: December 1, 2000
    Date of Patent: June 25, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Suman Preet Singh Khanuja, Sushil Kumar, Ajit Kumar Shasany, Jai Shankar Arya, Mahendra Pandurang Darokar, Monika Singh, Prachi Sinha, Soumya Awasthi, Subhash Chandra Gupta, Vivek Kumar Gupta, Madan Mohan Gupta, Ram Kishore Verma, Sweta Agarwal, Sunil Balkrishna Mansinghka, Suresh Haribhau Dawle
  • Patent number: 6409937
    Abstract: The invention relates to a process for the preparation of melt processable liquid crystalline terpolyesters of the general formula I by the in situ acetylation of a monomer selected from (4-hydroxyphenyl) acetic acid/ 3(4-hydroxyphenyl)propionic acid and hydroquinone/4,4′-biphenol/2,6-naphthylene diol followed by acidolysis polycondensation with or without a solvent and a catalyst, under reduced pressure for the efficient removal of acetic acid to effect higher molecular weight formation. Post polymerisation is effected at higher temperatures below the decomposition temperature purification by soxhlet extraction using solvent mixtures selected from acetone-alcohol, acetone-methylethyl ketone.
    Type: Grant
    Filed: March 28, 2000
    Date of Patent: June 25, 2002
    Assignees: Council of Scientific & Industrial Research, Department of Science and Technology
    Inventors: Vadakkethonippurathu Sivankutty Nair Prasad, Chennakkattu Krishna Sadasivan Pillai, Marayil Ravindranathan
  • Patent number: 6410762
    Abstract: The present invention relates to a process for the isolation of oryzanols from rice bran oil soap stock by (a) saponifying the oil present in soap stock with an alkali followed by neutralisation of the excess alkali, (b) converting the soap stock into anhydrous, porous soap noodles, (c) extracting the soap noodles with an organic solvent, (d) crystallising the crude unsaponifiable matter to remove impurities, (e) subjecting the residue to column chromatography to obtain an oryzanol rich fraction, and (f) recrystallising the oryzanol rich fraction using an organic solvent to obtain pure oryzanol.
    Type: Grant
    Filed: March 20, 2001
    Date of Patent: June 25, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Kasturi Venkata Sesha Adinarayana Rao, Bhamidipati Venkata Surya Koppeswara Rao, Narayana Balagopala Kaimal Thengumpillil
  • Patent number: 6410681
    Abstract: A process for preparation of alternating polyesteramides comprises reacting carbon monoxide, an aminohydroxy compound and an aromatic polyhalide having at least two halide atoms covalently bonded to an aromatic ring. The said process is conducted in the presence of a solvent, a catalyst and a base.
    Type: Grant
    Filed: January 30, 2001
    Date of Patent: June 25, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Ashutosh Anant Kelkar, Shrikant Madhukar Kulkarni, Raghunath Vitthal Chaudhari
  • Patent number: 6410282
    Abstract: The invention relates to a method for enhancing levels of polyunsaturated fatty acid levels in thraustochytrid fungi, using media supplemented with polyvinyl pyrrolidone (PVP) to increase viscosity and which comprises: (a) providing a thraustochytrid fungus strain NIO-TH 21, corresponding to the species Ulkenia radiata Gaertner, being the culture with Accession No. AB22115 of the National Institute of Bioscience and Human-Technology, Japan; (b) inoculating the above said strain in a culture medium; (c) growing the culture for 2 days at a temperature ranging from 25 to 30° C.; (d) obtaining the cultures for use as innoculum using the above said medium to inoculate a medium with different concentrations of polyvinyl pyrrolidone (PVP); (e) growing the culture separately for 2 to 5 days at a temperature ranging from 25 to 30° C.; and (f) harvesting the cells from the above culture by centrifugation and extracting the enhanced amounts of docosahexaenoic acid (DHA) and eicosapentaenoic acids (EPA).
    Type: Grant
    Filed: March 30, 2000
    Date of Patent: June 25, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Seshagiri Raghu Kumar, Dorai Rajasingam Chandramohan, Ehrlich Desa
  • Publication number: 20020076815
    Abstract: A bio-reactor for enhancing the biomass yield using a closed sterile vessel having a medium, said reactor comprising a central shaft, a support matrix oriented horizontally and dividing the vessel into an upper and a lower chamber, a means for stirring selected from turbine-2,4,6-impeller; marine blade impeller; helical blade impeller; mounted onto the central shaft and located at a predetermined distance from the support matrix so as to generate both radially and axially directed volumetric flow of the media; and at least two semi-circular sparges located both in the upper and lower compartments of the vessel at a predetermined distance from the support matrix.
    Type: Application
    Filed: December 15, 2000
    Publication date: June 20, 2002
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Suchitra Banerjee, Arun Kumar Kukreja, Praveen Chandra Verma, Atul Prakash Kahol, Sushil Kumar
  • Publication number: 20020077366
    Abstract: The present invention provides novel cationic amphiphiles containing novel N-hydroxyalkyl group and therapeutic formulations containing the said amphiphiles that are capable of facilitating transport of biologically active molecules into cells.
    Type: Application
    Filed: January 11, 2002
    Publication date: June 20, 2002
    Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
    Inventors: Rajkumar Banerjee, Prasanta Kumar Das, Gollapudi Venkata Srilakshmi, Nalam Madhusudhana Rao, Arabinda Chaudhuri
  • Patent number: 6406882
    Abstract: An immobilized microbial consortium is formulated which comprises of a synergistic mixture of all the bacterial strains of Aeromonas hydrophila, Pseudomonas fluorescens, Pseudomonas aeruginosa, Bacillus circulans, Yersinia enterocolitica, Enterobacter cloaca and Bacillus brevis. The formulated microbial consortium is immobilized on a non-biodegradable and economically cheaper support. The said immobilized microbial consortium is used for the biodegradation of synthetic phenol as well as phenol present in petroleum refinery effluent. The results of biodegradation obtained with the microbial consortium immobilized on coconut fiber are compared with those obtained with microbial consortium immobilized on well known support. The coconut fiber used for immobilization proved to be a better support than a well known support such as calcium alginate.
    Type: Grant
    Filed: March 27, 2000
    Date of Patent: June 18, 2002
    Assignee: Council for Scientific and Industrial Research
    Inventors: Rita Kumar, Alka Sharma, Archana Kumar
  • Patent number: 6406852
    Abstract: The present invention relates to a process for uniform and efficient delivery of metal projectiles into living cells and tissue of plants and animals, by bombarding the cells with biological coated on metal bead particles. The metal bead particles are heated in dry oven to high temperature, prior to coating with DNA and by substituting ethanol with isopropanol while coating the particles with DNA, to give several fold higher expression of the nucleic acid delivered into cells.
    Type: Grant
    Filed: June 22, 2000
    Date of Patent: June 18, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Rakesh Tuli, Samir V. Sawant
  • Patent number: 6407797
    Abstract: The invention relates to a method for the preparation of a polymer coated long duration optical memory device having applications in ferroelectric liquid crystal materials, the said method comprising the steps of forming patterns of different shapes and configurations on a glass substrate coated with indium tin oxide by lithographic methods to obtain an effective electrode area of at least 5 mm2; depositing an antireflection coating on external surfaces of glass substrates followed by coating the patterned glass substrate with a polymer selected from the polyamide group of nylon 6/6 and nylon 6/9 in the thickness range of 900 Å-1100 Å; baking the coated substrate followed by hard rubbing of the polymer coated surface; coating one of the substrates with a spacer selected from photoresist having thickness in the range of 1 &mgr;m to 3 &mgr;m; inserting a ferroelectric liquid crystal material in the space between the coated glass substrates, followed by sealing the sandwiched glass substrates at the
    Type: Grant
    Filed: November 4, 1999
    Date of Patent: June 18, 2002
    Assignee: Council of Scientific & Industrial Research
    Inventors: Ashok M. Biradar, Sukhwant S. Bawa, Ereuvassi P. Haridas, Subhas Chandra
  • Patent number: 6403344
    Abstract: The present invention provides an enzymatic process for the preparation of an acetylated phospholipid from a lecithin by acetylating the lecithin in the presence of vinyl acetate and a catalyst comprising lipase from Mucor miehei having 1,3-position specificity, separating the desired acetylated phospholipid.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: June 11, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Sri Lakshmi Karuna Marellapudi, Vandana Vemulapalli, Vijayalakshmi Penumarthy, Badari Narayana Prasad Rachapudi
  • Patent number: 6403833
    Abstract: The present invention provides a single step process for the preparation of p-aminophenol by hydrogenation of nitrobenzene in presence of an aqueous acid over a mono or bimetallic nickel catalyst at a temperature in the range of 80-120° C. for a period of 1 to 4 hrs. The resulting reaction mixture is extracted with an organic solvent like ethyl acetate, cyclohexane or toluene to separate the aqueous layer containing PAP and neutralizing it with ammonia solution to recover the solid p-aminophenol.
    Type: Grant
    Filed: January 30, 2001
    Date of Patent: June 11, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Chandrashekhar Vasant Rode, Manisha Jagdeeshrao Vaidya, Raghunath Vitthal Chaudhari
  • Patent number: 6402992
    Abstract: This invention relates to the preparation of free standing film of conducting polyaniline of varied thickness. The conducting polyaniline film is obtained by use of a functionalised aromatic sulphonic acid as primary dopant and a halosubstituted phenol as secondary dopant. The emeraldine base, primary dopant and secondary dopant are mixed in an appropriate amount and stirred. The resulted homogeneous thick viscous solution cast yields conducting polyaniline film of conductivity more than 10 S/cm.
    Type: Grant
    Filed: March 27, 2001
    Date of Patent: June 11, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Konda Kannan Satheesh Kumar, Geetha Sivasubramanian, Dinesh Chandra Trivedi
  • Patent number: 6398841
    Abstract: The present invention provides a novel ecological method of phyto-remediation of alkaline ad chemically degraded soils, said method comprising the steps of dispersing biomass obtained from Pelargonium sp. in alkaline or chemically degraded soil.
    Type: Grant
    Filed: February 2, 2001
    Date of Patent: June 4, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Rajender Singh Sangwan, Bali Ram Tyagi, Neelam Singh Sangwan
  • Publication number: 20020064864
    Abstract: The invention relates to a microbial composition for the neutralization of alkaline waste waters by biological means and a method of neutralization of alkaline waste waters using a synergistic mixture of the bacterial strains of Bacillus alkalophilus and Bacillus sp.
    Type: Application
    Filed: May 29, 2001
    Publication date: May 30, 2002
    Applicant: Council of Scientific and Industrial Research
    Inventors: Rita Kumar, Anil Kumar, Alka Sharma, Sharad Vishwanath Gangal, Santosh Dayaram Makhijani
  • Patent number: 6393763
    Abstract: The invention provides a method for maximization of artemisinin yield of the plant Artemisia annua, said method comprising sowing seeds of Artemisia annua plant on raised bed nursery during second and third week of December and maintaining the moisture throughout; transplanting seedlings thus obtained bearing at least 5-15 leaves into the main field fertilized with fertilizer, preferably NPK @ 80,40,40 kg/ha to achieve a population density of 50,000 to 200,000 per ha followed by light irrigation in the second week of March and irrigation every fortnight thereafter; harvesting the crop four times by cutting the plant tops leaving 75-100 cm part of plant for further regeneration, the said harvests are performed in a manner that the first harvest is done in fourth week of May, second harvest in third week of July, third harvest in second week of September and fourth harvest in third week of October of each year; and at each harvesting time care is taken to care at least one green branch, and extracting ar
    Type: Grant
    Filed: March 30, 2000
    Date of Patent: May 28, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Sushil Kumar, Shiv Kumar Gupta, Madan Mohan Gupta, Ram Kishor Verma, Dharam Chand Jain, Ajit Kumar Shasany, Mahendra Pandurang Darokar, Suman Preet Singh Khanuja
  • Patent number: 6395534
    Abstract: The invention relates to a biologically pure culture of white rot lignin-modifying fungus Flavodon flavus for simultaneous decolorization and detoxification of molasses spent wash or water/soil contaminated with molasses spent wash. The Flavodon flavus has been deposited at the National Institute of Oceanography, Goa, India, bearing Accession No. NIOCC #312 and has also been deposited at Agricultural Research Service Culture Collection (NRRL), 1815 North University Street, Peoria, Ill. 61604, U.S.A., bearing Accession No. NRRL 30302 on Mar. 10, 2000.
    Type: Grant
    Filed: December 8, 1999
    Date of Patent: May 28, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Chandralata Raghukumar, Trevor M. D'Souza, R. Greg Thorn, C. A. Reddy