Patents Assigned to CRAF Sud
  • Hydrazono penicillin derivatives
    Patent number: 4231927
    Abstract: Hydrazono penicillin derivatives of the formula ##STR1## wherein R represents phenyl optionally substituted, 2- or 3- thienyl optionally substituted, or 2- or 3-furyl optionally substituted, R.sub.1 represents hydrogen, alkyl containing from 1 to 4 carbon atoms, or phenyl, and R.sub.2 represents hydrogen, pivaloyloxymethyl, or 1-(ethoxycarbonyloxy)ethyl radical. The compounds have antibacterial activity against gram-negative and gram-positive microorganisms. Methods of preparation are also disclosed.
    Type: Grant
    Filed: June 7, 1978
    Date of Patent: November 4, 1980
    Assignee: CRAF Sud
    Inventors: Riccardo Monguzzi, Giorgio Pifferi, Mario Pinza, Giampietro Broccali
  • Hydrazono derivatives of cephalosporins
    Patent number: 4178444
    Abstract: Hydrazono derivatives of cephalosporins of the formula ##STR1## wherein R is phenyl optionally substituted, 2- or 3-thienyl optionally substituted, or 2- or 3-furyl optionally substituted, R.sub.1 is hydrogen or alkyl having from 1 to 4 carbon atoms, and R.sub.2 is hydrogen, acetoxy, carbamoyloxy or a heterocyclic nucleus preferably bounded through a sulphur atom to the methylene group. The compounds have bactericidal activity. Methods of preparation are also disclosed.
    Type: Grant
    Filed: June 7, 1978
    Date of Patent: December 11, 1979
    Assignee: CRAF Sud
    Inventors: Riccardo Monguzzi, Giorgio Pifferi, Mario Pinza, Giampietro Broccali