Patents Assigned to CREARENE LTD.
  • Patent number: 9248112
    Abstract: The present invention relates to a haemodialysis solution or concentrate thereof comprising creatine compound(s) and the use of creatine compound(s) for preparing a dialysis solution or concentrate thereof. Furthermore, the present invention is directed to a method for preparing creatine-containing dialysis solutions and concentrates. In addition, the present invention is directed to a method for treating patients with dialysis dependent renal failure with creatine compounds and to provide a variety of significant health benefits and improvement of life quality parameters for dialysis patients. This is achieve by supporting and improving the physiological functions of the patients organs and cells via creatine compounds delivery to the patients, and by protecting organs and cells (specifically including blood cells) of these patients from deleterious effects of a variety of endogenous or exogenous cellular stressors that are linked to the disease state or to the clinical treatment modalities.
    Type: Grant
    Filed: March 10, 2010
    Date of Patent: February 2, 2016
    Assignee: CREARENE LTD.
    Inventors: Michael Möddel, Theo Wallimann
  • Patent number: 8791078
    Abstract: The invention relates to a dialysis solution for haemodialysis or peritoneal dialysis, said solution having a theoretical osmolarity within the range of from 250 to 550 mosm/L and a pH value within the range of from 4.9 to 8.0, said solution comprising a creatine compound and one or more electrolytes, wherein the concentration of the creatine compound is not more than 50 mM.
    Type: Grant
    Filed: July 21, 2010
    Date of Patent: July 29, 2014
    Assignee: Crearene Ltd.
    Inventor: Jan Bulle
  • Publication number: 20120135943
    Abstract: The invention relates to a dialysis solution for haemodialysis or peritoneal dialysis, said solution having a theoretical osmolarity within the range of from 250 to 550 mosm/L and a pH value within the range of from 4.9 to 8.0, said solution comprising a creatine compound and one or more electrolytes, wherein the concentration of the creatine compound is not more than 50 mM.
    Type: Application
    Filed: July 21, 2010
    Publication date: May 31, 2012
    Applicant: CREARENE LTD.
    Inventors: Ulrich Kirschner, Jan Bulle
  • Publication number: 20120101069
    Abstract: The present invention relates to a haemodialysis solution or concentrate thereof comprising creatine compound(s) and the use of creatine compound(s) for preparing a dialysis solution or concentrate thereof. Furthermore, the present invention is directed to a method for preparing creatine-containing dialysis solutions and concentrates. In addition, the present invention is directed to a method for treating patients with dialysis dependent renal failure with creatine compounds and to provide a variety of significant health benefits and improvement of life quality parameters for dialysis patients. This is achieve by supporting and improving the physiological functions of the patients organs and cells via creatine compounds delivery to the patients, and by protecting organs and cells (specifically including blood cells) of these patients from deleterious effects of a variety of endogenous or exogenous cellular stressors that are linked to the disease state or to the clinical treatment modalities.
    Type: Application
    Filed: March 10, 2010
    Publication date: April 26, 2012
    Applicant: CREARENE LTD.
    Inventors: Michael Moeddel, Theo Wallimann