Abstract: Embodiments of the present invention relate to non-invasive methods and compositions for collecting detecting, measuring, and identifying target molecules. In some embodiments, methods and compositions relate to target molecules in gastrointestinal lavage fluid or feces.
Type:
Application
Filed:
December 15, 2022
Publication date:
February 8, 2024
Applicant:
Creatics LLC
Inventors:
Lewis K. Pannell, Jana Rocker, Carlo Contreras, Jack Di Palma
Abstract: The present invention relates to non-invasive methods for the diagnosis and prognosis of pancreatic cancer. In some embodiments, such methods and compositions relate to particular pancreatic cancer biomarkers and combinations thereof.
Abstract: Described herein are non-invasive or minimally invasive methods and compositions for collecting and assessing samples for detection of gastrointestinal (GI) tract cancers and pancreatic cancers. Samples comprising gastrointestinal lavage fluid (GLF) are obtained from subjects and screened against a glycan microarray to reveal disease-specific glycan-binding patterns by immunoglobulins contained in the GLF, especially immunoglobulin A (IgA). The disease-specific glycan-binding patterns include a disease-specific glycan or subset of glycans from the microarray that are bound by the immunoglobulins in GLF at highest intensities or at lowest intensities, as well as one or more glycan motifs found within this disease-specific subset of glycans.
Abstract: Embodiments of the present invention relate to non-invasive methods and compositions for collecting detecting, measuring, and identifying target molecules. In some embodiments, methods and compositions relate to target molecules in gastrointestinal lavage fluid or feces.
Type:
Application
Filed:
January 10, 2019
Publication date:
August 8, 2019
Applicant:
Creatics LLC
Inventors:
Lewis K. Pannell, Jana Rocker, Carlo Contreras, Jack Di Palma
Abstract: The present invention relates to non-invasive methods for the diagnosis and prognosis of pancreatic cancer. In some embodiments, such methods and compositions relate to particular pancreatic cancer biomarkers and combinations thereof.
Abstract: Embodiments of the present invention relate to non-invasive methods and compositions for collecting detecting, measuring, and identifying target molecules. In some embodiments, methods and compositions relate to target molecules in gastrointestinal lavage fluid or feces.
Type:
Grant
Filed:
September 12, 2011
Date of Patent:
March 12, 2019
Assignee:
Creatics LLC
Inventors:
Lewis Pannell, Jana Rocker, Carlo Contreras, Jack Di Palma
Abstract: Embodiments of the present invention relate to non-invasive methods and compositions for collecting detecting, measuring, and identifying target molecules. In some embodiments, methods and compositions relate to target molecules in gastrointestinal lavage fluid or feces.
Type:
Application
Filed:
September 12, 2011
Publication date:
November 20, 2014
Applicant:
Creatics LLC
Inventors:
Lewis Pannell, Jana Rocker, Carlos Contreras, Jack Di Palma