Patents Assigned to Credo Diagnostics Biomedical Pte. Ltd.
-
Patent number: 12023677Abstract: The present invention provides a sample tube for polymerase chain reaction. The sample tube includes a sample tube body having an annular side wall and a bottom wall connected to annular side wall, wherein the annular side wall and the bottom wall form an accommodating space for accommodating a reaction mixture; and a first extension member extending from the bottom wall to the accommodating space, wherein, to carry out PCR, the reaction mixture immerses the first extension member, such that the light from the light source enters into the reaction mixture via the bottom and the bottom wall of the sample tube and the first extension member sequentially.Type: GrantFiled: August 18, 2020Date of Patent: July 2, 2024Assignee: Credo Diagnostics Biomedical Pte. Ltd.Inventors: Ying-Ta Lai, Yu-Cheng Ou, Jim-Yi Liao, Yi-Hsi Chen
-
Patent number: 11878301Abstract: An analysis cartridge includes a first cover, a second cover, a plurality of containers, a plurality of fluid tunnels and a rotary valve. The second cover has two opposite surfaces, a plurality of first through holes and a second through hole individually penetrate through the two opposite surfaces, and the first cover is attached to the second cover. The plurality of containers are disposed between the first cover and the second cover, with each of the containers being aligned to and filled in the first through holes. The plurality of the fluid tunnels are disposed on the first cover, and each of which is individually connected with a first pipette. The rotary valve is rotatably disposed between the first cover and the second cover to correspond to the second through hole, and a flow channel disposed on the rotary valve is connected with the containers individually.Type: GrantFiled: December 8, 2021Date of Patent: January 23, 2024Assignee: Credo Diagnostics Biomedical Pte. Ltd.Inventors: Ying-Ta Lai, Yu-Cheng Ou, Jim-Yi Liao, Shu-Hong Huang, Fan-Yun Huang, Ruei-Yi Tsai, Li-Yu Hsiung
-
Publication number: 20230383337Abstract: An analysis cartridge and an analysis method, the analysis cartridge includes a first cover, a second cover, containers, a fluid tunnels and a rotary valve. The second cover has two opposite surfaces, a plurality of first through holes and a second through hole individually penetrate through the two opposite surfaces, and the first cover is attached to the second cover. The plurality of containers are disposed between the first cover and the second cover, with each of the containers being aligned to and filled in the first through holes. The plurality of the fluid tunnels is disposed on the first cover, and each of which is individually connected with a first pipette. The rotary valve is rotably disposed between the first cover and the second cover to correspond to the second through hole, and a flow channel disposed on the rotary valve is connected with the containers individually.Type: ApplicationFiled: August 16, 2023Publication date: November 30, 2023Applicant: Credo Diagnostics Biomedical Pte. Ltd.Inventors: Yu-Cheng Ou, Han-Yi Chen, Bing-Hsien Tsai, Kuan-Ying Chen, Chia-Chou Tseng
-
Patent number: 11680291Abstract: The present invention discloses a Polymerase Chain Reaction (PCR) apparatus for real-time detecting of one or more fluorescent signals. According to the apparatus, the PCR is performed by controlling heating and cooling intervals of a reagent container receiving space. With the aid of an added specific probe and fluorescent material, as well as a light source and a spectrometer, a generated fluorescent signal is detected. Meanwhile, the apparatus is also pre-loaded with an algorithm configured to analyze and quantify the fluorescent signal in a real-time manner.Type: GrantFiled: March 12, 2020Date of Patent: June 20, 2023Assignee: CREDO DIAGNOSTICS BIOMEDICAL PTE, LTD.Inventors: Ying-Ta Lai, Yu-Cheng Ou, Chun-Te Wu, Yu-Wen Huang, Han-Yi Chen
-
Patent number: 11639532Abstract: The present invention discloses a method for detecting Influenza A virus and Influenza B virus in a suspected sample by detecting the matrix gene and the non-structural gene, respectively. The signals can be detected by a fluorescent detection system.Type: GrantFiled: October 30, 2019Date of Patent: May 2, 2023Assignee: CREDO DIAGNOSTICS BIOMEDICAL PTE. LTD.Inventors: Yih-Jyh Shann, Chia-Hsin Su
-
Patent number: 11624641Abstract: What is disclosed in the present invention is to provide a quantitative transfer pipette structure, wherein an anti-backflow compartment is configured in the first bulb. The dimensions and locations of the first bulb, the second bulb and the third bulb are specifically configured to aspirate and transfer a specific volume of the liquid to a container, mix the liquid with the substance in the container by pressing and releasing the specific bulbs, so as to achieve the effects of precise quantification and sufficient mixing.Type: GrantFiled: August 3, 2020Date of Patent: April 11, 2023Assignee: Credo Diagnostics Biomedical Pte. Ltd.Inventors: Ying-Ta Lai, Yu-Cheng Ou, Jim-Yi Liao, Fan-Yun Huang, Yi-Hsi Chen
-
Patent number: 11565268Abstract: The present invention discloses a convective PCR apparatus by using a transparent conductive thin film to replace the traditional metal heater. The PCR reaction is activated when the container with reagents contacted the heated transparent conductive thin film and the temperature inside the container raised to initiate the convective circulation. Also, the present invention could apply for a quantitative PCR reaction by adding a specific probe, a fluorescent dye, a light source, or a photon receiver.Type: GrantFiled: December 16, 2018Date of Patent: January 31, 2023Assignee: Credo Diagnostics Biomedical Pte. Ltd.Inventors: Ying-Ta Lai, Yu-Cheng Ou, Ming-Lung Hung, Cheng-Yueh Chung, Han-Yi Chen
-
Publication number: 20220388000Abstract: An analysis cartridge includes a first cover, a second cover, a plurality of containers, a plurality of fluid tunnels and a rotary valve. The second cover has two opposite surfaces, a plurality of first through holes and a second through hole individually penetrate through the two opposite surfaces, and the first cover is attached to the second cover. The plurality of containers are disposed between the first cover and the second cover, with each of the containers being aligned to and filled in the first through holes. The plurality of the fluid tunnels are disposed on the first cover, and each of which is individually connected with a first pipette. The rotary valve is rotatably disposed between the first cover and the second cover to correspond to the second through hole, and a flow channel disposed on the rotary valve is connected with the containers individually.Type: ApplicationFiled: December 8, 2021Publication date: December 8, 2022Applicant: Credo Diagnostics Biomedical Pte. Ltd.Inventors: Ying-Ta Lai, Yu-Cheng Ou, Jim-Yi Liao, Shu-Hong Huang, Fan-Yun Huang, Ruei-Yi Tsai, Li-Yu Hsiung
-
Publication number: 20220389402Abstract: The present disclosure relates to a method and an apparatus for opening the external layer structure of cells using laser, wherein the short pulse laser excited from a laser diode is collimated via the optical lens and concentrated at a focus, a biological sample which is fixed on the focus or moves through the focus is treated with the concentrated short pulse laser, so that the cell membrane or cell wall of cells in the sample is broken.Type: ApplicationFiled: June 30, 2021Publication date: December 8, 2022Applicant: Credo Diagnostics Biomedical Pte. Ltd.Inventors: Ying-Ta Lai, Yu-Cheng Ou, Yi-Hsi Chen, Chung-Wei Tsai, Kuan-Ying Chen, Ruei-Yi Tsai, Chih-Yuan Chen
-
Publication number: 20200392559Abstract: The present invention discloses a Polymerase Chain Reaction (PCR) apparatus for real-time detecting of one or more fluorescent signals. According to the apparatus, the PCR is performed by controlling heating and cooling intervals of a reagent container receiving space. With the aid of an added specific probe and fluorescent material, as well as a light source and a spectrometer, a generated fluorescent signal is detected. Meanwhile, the apparatus is also pre-loaded with an algorithm configured to analyze and quantify the fluorescent signal in a real-time manner.Type: ApplicationFiled: March 12, 2020Publication date: December 17, 2020Applicant: CREDO DIAGNOSTICS BIOMEDICAL PTE. LTD.Inventors: YING-TA LAI, YU-CHENG OU, CHUN-TE WU, YU-WEN HUANG, HAN-YI CHEN
-
Patent number: 10688497Abstract: The present invention discloses an apparatus for performing PCR by thermal convection. The device includes a first bracket, a second bracket, a temperature sensing device, a power supplying device, a processor and an accommodation space. The device uses transparent conductive film to replace conventional thermostat metal stock to perform a heat process required in the PCR or RT-PCR process. The device further uses a reagent container whose bottom portion contacts the transparent conductive film and being heated by the transparent conductive film to establish a thermal circulation in the reagent container. The device can qualify or quantify the product of PCR or RT-PCR process by further incorporating specific probes, fluorescence material, light source, light receiver and light regulator.Type: GrantFiled: September 7, 2017Date of Patent: June 23, 2020Assignee: Credo Diagnostics Biomedical Pte. Ltd.Inventors: Yu-Cheng Ou, Cheng-Yueh Chung, Wei-Hao Liu, Han-Yi Chen