Patents Assigned to CRESCENDO BIOSCIENCE, INC.
  • BIOMARKERS AND METHODS FOR ASSESSING MYOCARDIAL INFARCTION AND SERIOUS INFECTION RISK IN RHEUMATOID ARTHRITIS PATIENTS
    Publication number: 20210199671
    Abstract: Provided herein are methods for assessing risk of infection or cardiovascular disease (CVD) in a subject with an inflammatory disease, e.g., rheumatoid arthritis. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers with or without additional clinical variables to assess infection and CVD risk. Also provided are uses of inflammatory biomarkers for guiding treatment decisions.
    Type: Application
    Filed: March 15, 2021
    Publication date: July 1, 2021
    Applicants: CRESCENDO BIOSCIENCE, INC., UAB RESEARCH FOUNDATION
    Inventors: Kerri FORD, Jeffrey R. CURTIS
  • Biomarkers and methods for assessing myocardial infarction and serious infection risk in rheumatoid arthritis patients
    Patent number: 10962552
    Abstract: Provided herein are methods for assessing risk of infection or cardiovascular disease (CVD) in a subject with an inflammatory disease, e.g., rheumatoid arthritis. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers with or without additional clinical variables to assess infection and CVD risk. Also provided are uses of inflammatory biomarkers for guiding treatment decisions.
    Type: Grant
    Filed: March 10, 2020
    Date of Patent: March 30, 2021
    Assignees: CRESCENDO BIOSCIENCE, INC., UAB RESEARCH FOUNDATION
    Inventors: Kerri Ford, Jeffrey R. Curtis
  • BIOMARKERS AND METHODS FOR MEASURING AND MONITORING JUVENILE IDIOPATHIC ARTHRITIS ACTIVITY
    Publication number: 20200300853
    Abstract: Biomarkers useful for assessing inflammatory disease or flare activity, in particular in juvenile idiopathic arthritis, are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.
    Type: Application
    Filed: June 9, 2020
    Publication date: September 24, 2020
    Applicant: CRESCENDO BIOSCIENCE, INC.
    Inventors: Scott Eastman, Eric Sasso
  • BIOMARKERS AND METHODS FOR ASSESSING MYOCARDIAL INFARCTION AND SERIOUS INFECTION RISK IN RHEUMATOID ARTHRITIS PATIENTS
    Publication number: 20200292559
    Abstract: Provided herein are methods for assessing risk of infection or cardiovascular disease (CVD) in a subject with an inflammatory disease, e.g., rheumatoid arthritis. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers with or without additional clinical variables to assess infection and CVD risk. Also provided are uses of inflammatory biomarkers for guiding treatment decisions.
    Type: Application
    Filed: March 10, 2020
    Publication date: September 17, 2020
    Applicants: CRESCENDO BIOSCIENCE, INC., UAB RESEARCH FOUNDATION
    Inventors: Kerri FORD, Jeffrey R. CURTIS
  • Biomarkers and methods for measuring and monitoring juvenile idiopathic arthritis activity
    Patent number: 10718765
    Abstract: Biomarkers useful for assessing inflammatory disease or flare activity, in particular in juvenile idiopathic arthritis, are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: July 21, 2020
    Assignee: CRESCENDO BIOSCIENCE, INC.
    Inventors: Scott Eastman, Eric Sasso