Patents Assigned to Critical Care Diagnostics, Inc.
  • SOLUBLE HUMAN ST-2 ANTIBODIES AND ASSAYS
    Publication number: 20110256635
    Abstract: Provided herein are antibodies and antigen-binding antibody fragments that bind to human soluble Growth Stimulation-Expressed Gene 2 (ST2) protein, kits containing these antibodies and antibody fragments, and methods of using these antibodies and antibody fragments.
    Type: Application
    Filed: April 8, 2011
    Publication date: October 20, 2011
    Applicant: CRITICAL CARE DIAGNOSTICS, INC.
    Inventor: James V. Snider
  • Predicting mortality and detecting severe disease
    Patent number: 7998683
    Abstract: Measurement of circulating ST2 and/or IL-33 concentrations is useful for the prognostic evaluation of subjects, in particular for the prediction of adverse clinical outcomes, e.g., mortality, and the detection of severe disease.
    Type: Grant
    Filed: April 24, 2007
    Date of Patent: August 16, 2011
    Assignee: Critical Care Diagnostics, Inc.
    Inventors: James V. Snider, Sven Jacobson
  • DIAGNOSIS OF PULMONARY AND/OR CARDIOVASCULAR DISEASE
    Publication number: 20100055683
    Abstract: Described are methods and kits for determining the likelihood of the presence of cardiovascular disease (CVD) or pulmonary disease (PD) in a subject using ST2/Interleukin 1 Receptor Like 1 (IL1RL1) and/or Interleukin 33 (IL-33), and a biomarker for CVD, e.g., a natriuretic peptide, e.g., brain natriuretic peptide (BNP), prohormone BNP (proBNP), N-Terminal proBNP (NT-proBNP), atrial natriuretic peptide (ANP), proANP, or NT-proANP.
    Type: Application
    Filed: May 2, 2007
    Publication date: March 4, 2010
    Applicant: CRITICAL CARE DIAGNOSTICS, INC.
    Inventors: James V. Snider, Sven Jacobson
  • DIAGNOSIS OF CARDIOVASCULAR DISEASE
    Publication number: 20100009356
    Abstract: This invention relates to methods for the detection of cardiovascular disease, e.g., acute coronary syndrome, heart failure and/or pulmonary embolism, in high body mass index (BMI) individuals, e.g., with a BMI of 25-29, or 30 or above, and those with impaired renal function.
    Type: Application
    Filed: May 1, 2007
    Publication date: January 14, 2010
    Applicant: CRITICAL CARE DIAGNOSTICS, INC.
    Inventors: James V. Snider, Sven Jacobson
  • INTERLEUKIN-33 (IL-33) FOR THE DIAGNOSIS AND PROGNOSIS OF CARDIOVASCULAR DISEASE
    Publication number: 20090305265
    Abstract: The present invention includes methods for the use of interleukin-33 (IL-33) in the diagnosis of cardiovascular conditions including acute coronary syndrome (ACS), myocardial infarction, and/or heart failure, angina, cardiac hypertrophy, arteriosclerosis, myocarditis, pancarditis, endocarditis, stroke and/or pulmonary embolism and the determination of the severity of such conditions (prognosis).
    Type: Application
    Filed: April 27, 2007
    Publication date: December 10, 2009
    Applicant: CRITICAL CARE DIAGNOSTICS, INC.
    Inventors: James V. Snider, Sven Jacobson
  • PREDICTING RISK OF MAJOR ADVERSE CARDIAC EVENTS
    Publication number: 20090264779
    Abstract: Measurement of circulating ST2 and natriuretic peptide (e.g., NT-proBNP) concentrations is useful for the prognostic evaluation of subjects, in particular for the prediction of adverse clinical outcomes, e.g., mortality, transplantation, and heart failure.
    Type: Application
    Filed: April 17, 2009
    Publication date: October 22, 2009
    Applicant: Critical Care Diagnostics, Inc.
    Inventors: James V. Snider, Eugene R. Heyman