Patents Assigned to CRL-SCI Corporation
  • PEPTIDES AND CONJUGATES FOR TREATMENT OF ARTHRITIS
    Publication number: 20220218806
    Abstract: The invention relates to peptide heteroconjugates useful in treating Rheumatoid Arthritis (RA). The peptide heteroconjugates include a portion of the Human aggrecan protein conjugated to an Immune Cell Binding Ligand (ICBL) by a direct bond or divalent linker. The peptide heteroconjugates including combinations thereof, can be used as a vaccination for RA when combined with an adjuvant and administered to a subject.
    Type: Application
    Filed: May 11, 2019
    Publication date: July 14, 2022
    Applicant: CRL-SCI Corporation
    Inventors: Daniel H. Zimmerman, Tibor T Glant, Katalin MIKECZ, Roy E Carambula