Abstract: An active implantable medical device, notably a device for pacing, resynchronization defibrillation and/or cardioversion, and/or a device for diagnosing patient conditions, having a predictive diagnosis of the patient's status. The device measures a physiologic parameter, notably the minute ventilation (MV); measures a physical parameter, notably the acceleration (G); discriminates between phases of activity and rest of the patient; and includes a memory containing a plurality of fields selectively updated by statistical processing. These fields are comprising one first set (22) containing data related to the patient's activity phases, and one second set (24) containing data related to the patient's rest phases.

Abstract: The invention relates to an implantable ventricular heart stimulator (10), comprising an at least partially electrically conductive housing (12), an electrode line terminal for connection of a ventricular defibrillation electrode line (20) and a terminal for a defibrillation electrode (26). According to the invention, the heart stimulator has a far-field electrocardiogram detection unit (70) which has a first input connected to the terminal for the ventricular defibrillation electrode and has a second input connected to the electrically conductive housing and designed or configured to generate a far-field electrocardiogram on the basis of the electric potentials applied to the two inputs during operation.

Abstract: The present disclosure generally relates to a method, a device, and a computer-readable storage medium for detecting heart beats from cardiac signals whose quality, expressed in terms of signal amplitude and signal-to-noise ratio, varies dynamically in time. Hence, a method, a device, and a computer-readable storage medium for detecting electrical signals originating from a human or animal heart is proposed. The method includes the following steps: a) identifying an initial indication of the event in at least one of the signal channels, b) deciding whether or not the identified initial indication confirms the event depending on the quality of the signal channels in which initial indications are identified; and c) determining a point-of-detection for the event depending on the quality of the signal channels and depending from the shape of the signal.

Abstract: An implantable cardiac prosthesis device conducting an analysis of a patient tolerance to a pacing mode favoring the spontaneous atrioventricular conduction is disclosed. The device operates in a dual chamber (DDD or biventricular) mode and in a pacing mode favoring the spontaneous atrioventricular conduction such as an AAI mode (10) with a ventricular sensing or a mode with hysteresis of the atrioventricular delay. The device controls (10-18) the conditional switching from one mode to the other. The device comprises a hemodynamic sensor, including an endocardial acceleration sensor, derives a hemodynamic index representative of the hemodynamic tolerance of the patient to the spontaneous atrioventricular conduction. The device controls inhibiting or (20) forcing the conditional switching of the device to the DDD (or biventricular) mode according to the evolution of the hemodynamic index.

Abstract: A device produces at least two distinct temporal components (Vbip, Vuni) from two separate endocardial electrogram EGM signals concurrently collected in the same cavity. A 2D non-temporal characteristic is determined from the variations of one of the temporal components (Vuni) versus the other (Vbip). The analysis of this characteristic allows detection of the possible presence of an anodal stimulation, causing a depolarization in a second cavity after stimulation delivered to a first heart chamber, opposite to the first. One possibility is to proceed by observing whether the non-temporal 2D characteristic is included or not within a predetermined domain defined in a coordinate frame corresponding to the space of the two temporal components.

Abstract: A medical device for characterizing the cardiac status of a patient equipped with a bi-ventricular pacing active implant device. The implant collects an endocardiac acceleration signal and searches for an optimal pacing configuration. This latter tests a plurality of different pacing configurations and delivers for each tested configuration parameters derived from the endocardiac acceleration peak (PEA). The device derives a patient clinical status from those parameters, the indication being representative of the patient's response to the cardiac resynchronization therapy. Those parameters include: the possibility to automatically get or not a valid optimal AV Delay among all the biventricular pacing configurations; a factor indicating the character sigmoid of the PEA/AVD characteristic; the average value of the PEA for the various configurations; and the PEA signal/noise ratio.

Abstract: An active implantable medical device (e.g., implantable pacemaker or defibrillator), for detection of QRS complexes in noisy signals. Functional units (12-16) collect, amplify, prefilter and convert from analog-to-digital an endocardial signal, and digital functional units (18) provide signal processing and analysis of the digitized signal, for delivery of an indicator corresponding to a signal peak detection representative of the presence of a QRS complex in the endocardial signal. A double threshold comparator (30) is employed, receiving as input (28) the digitized signal and outputting (40) the indicator of peak detection when, cumulatively: the amplitude (A) of the input signal exceeds a peak amplitude threshold (SA), and the peak amplitude threshold is exceeded for a period (W) greater than a peak width threshold (SW). The peak amplitude threshold (SA) is a variable adaptive threshold, according to a noise level calculated from the energy (RMS) of the input signal.

Abstract: An implantable cardiac electrostimulator includes an atrial sensing channel generating an atrial sense event signal upon detection of atrial activity, a ventricular sensing channel generating a ventricular sense event signal upon detection of ventricular activity, a VES detector detecting ventricular extrasystoles, atrial and ventricular stimulation pulse generators, and a stimulation control unit. The stimulation control unit determines scheduled delivery times of atrial stimulation pulses (T(A)) and/or ventricular stimulation pulses (T(V)), and triggers delivery if no atrial sense event signal arises before the end of an atrial escape interval (VAI) timing out at T(A), or if no ventricular sense event signal arises before the end of a ventricular escape interval (VEI) timing out at T(V). T(A) and T(V) depend upon detection of a ventricular extrasystole, and proper atrioventricular synchrony is maintained by setting a physiologically adequate A-V-delay between T(A) and T(V).

Abstract: A microlead implantable in a patient's venous, arterial or lymphatic networks for the detection and/or stimulation of tissue. The microlead has a diameter at most equal to 2 French (0.66 mm) and comprises at least one microcable (40) comprising a core cable (11) and an insulation layer (20) partially surrounding the core. The core is formed of a plurality of strands, and has a composite structure comprising a structuring material having high fatigue resistance, and a radiopaque material. A denuded area (30) is formed in the isolation layer (20) so as to form at least one electrode for stimulation detection. The microlead is shaped at the electrodes (30) according to at least one electrical contact and mechanical stabilization preshape, and has a gradual decrease of rigidity along the microlead between its proximal portion and its distal portion.

Abstract: An implantable medical device includes a sensor configured to generate an endocardial acceleration (EA) signal representative of activity of a patient's heart. The device further includes one or more circuits configured to identify within the EA signal at least one EA signal component corresponding to at least one peak of endocardial acceleration, and extract from the at least one EA signal component at least two characteristic parameters. The one or more circuits are further configured to generate a composite index based on a combination of the at least two characteristic parameters, determine a plurality of values of the composite index for a plurality of pacing configurations, and select a current pacing configuration from among the plurality of pacing configurations based on the plurality of values of the composite index.

Abstract: A remotely programmable personal device, in particular a programmable implantable medical device, e.g., a cardiac pacemaker, a defibrillator, a cardioverter or the like. A system for remote programming of such a personal medical device and a method for remote programming of a programmable personal device.

Abstract: A component including at least one active element hermetically encapsulated in a cavity formed between a support and a cover, in which the support and the cover are made from an electrically conductive material, and are insulated electrically from one another, and include a first electrical connection between the active element and the support, and a second electrical connection, separate from the first connection, between the active element and the cover, and in which: the active element is securely attached to the support through a dielectric layer positioned between the support and the active element, and between the support and the cover; the second electrical connection includes a second portion of electrically conductive material electrically connected to the cover, positioned on the dielectric layer and electrically in contact with an electrically conductive sealing bead providing hermetic secure attachment of the cover to the support.

Abstract: A single-chamber implantable device for detecting a patient's atrial activity using a monobody lead is disclosed. The monobody lead (10) includes a ventricular coil (16), a supraventricular coil (18), a distal electrode (14) forming three electrodes for detecting depolarization signals. A generator (12) of the implantable device collects a first unipolar signal (20) between the ventricular coil and the generator housing and a second unipolar signal (22) between the supraventricular coil and the generator housing. An independent component analysis is performed to the detected depolarization signals to determine an estimated atrial activity signal from the first and second unipolar signals.

Abstract: A lead for an implantable cardiac prosthesis having an integrated protection against the effects of magnetic resonance imaging (“MRI”) fields. A protection circuit (26) may be placed at the distal end of the lead comprises a resistive component (28) interposed between the electrode (E1, E2) and the distal end of the conductor (22, 24) associated with this electrode. A normally-open controlled active switch (34, 36) may allow in its closed state to short-circuit the resistive component. A control stage (32) may be coupled to the conductors and detect the voltage of a stimulation pulse applied on the conductor(s), and selectively control by this voltage the closing of the active switch for a duration at least equal to the duration of detected stimulation pulse.

Abstract: An active medical device using non-linear filtering for the reconstruction of a surface electrocardiogram (ECG) from an endocardial electrogram (EGM) is disclosed. The device for the reconstruction of the surface ECG comprises: a plurality of inputs, receiving a corresponding plurality of EGM signals from endocardial or epicardial electrogram (x1[n], x2[n]), each collected on a respective EGM derivation of a plurality of EGM derivations, and at least one output delivering a reconstructed surface ECG electrocardiogram signal (y[n]), related to an ECG derivation, and a non-linear digital filter (12?, 12?, 14) with a transfer function that determines the reconstructed ECG signal based on said plurality of input EGM signals. The non-linear digital filter includes a Volterra filter type (12, 12?, 12?) whose transfer function includes a linear term (h1) and at least one quadratic (h2) and/or cubic (h3) term(s).

Abstract: The invention relates to a therapy system and a therapy device having at least one data communication interface which can operate in various data transmission modes and cooperates with a data communication control unit. The data communication interface can change from one data transmission mode to another without interruption of an existing data link. The change is controlled by the data communication control unit as a function of predefined selection criteria.

Abstract: A screwless quick connection system for connecting a lead connector to a generator of an active implantable medical device is shown and described. The connector head includes a housing receiving a plug of a lead connector. A mechanism for locking the plug into the housing is provided by a U-folded leaf spring. Each branch of the U is provided with a respective hole sized so that the plug passes through the holes on both branches when it is inserted into the housing. The blade is deformable between a free state, in the absence of plug, and a deformed state, with the plug inserted therein. In the free state, both holes are misaligned, while in the deformed state they are aligned. In this way, an edge of both holes exerts by reaction a radial stress force against the smooth outer surface of the plug inserted therein.

Abstract: An apparatus and method for searching and selecting an RF telemetry channel to establish a link between an active medical device and a remote device is disclosed. In the absence of any communication request, the available communication channels are scanned periodically to perform a long-term analysis. For each channel, a long-term indicator (iCLT) that is representative of a long-term availability is generated. Upon receipt of a communication request from the remote device, the communication channels are scanned to perform a short-term analysis, a short-term indicator (iCCT) that is representative of the short-term availability is generated. The short-term indicator is weighted by the long-term indicator, to generate a weighted short-term indicator (iCP). Based on the weighted short-term indicator, a communication channel is selected as the communication channel for the communication request.

Abstract: Implantable medical device (10) having control unit (20) connected to bidirectional wireless interface (18) and magnetic interface (16). Bidirectional wireless interface configured for bidirectional wireless data transmission via alternating electric field between medical device and an external device and may assume at least one OFF and one ON state, whereby wireless data transmission is possible only in ON state and function interface requires little or no energy in OFF state. Magnetic interface configured to constantly receive control signals transmitted via an alternating magnetic field from the external device. Magnetic interface configured to receive/process a data transmission start signal, such that magnetic interface or control unit generates a wireless interface activation. The bidirectional wireless interface is at least indirectly connected to the magnetic interface and is configured to switch from OFF to ON state in response to the wireless interface activation signal.

Abstract: An implantable medical device detects a strong static magnetic field associated with an MRI imaging instrument and operates in a safekeeping operating mode. The device includes an electronic circuit for the detection/stimulation of a cardiac activity, a weak field sensor detecting the presence of a first magnetic field of a permanent magnet being located in proximity to the device, a strong field sensor detecting the presence of a second magnetic field of an MRI imaging instrument during the course of an MRI examination.