Abstract: Ditosylate salts of N2-(2-ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine, and crystalline forms thereof; processes for the preparation of the new salt forms; and their use as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer.
Type:
Grant
Filed:
June 6, 2019
Date of Patent:
April 23, 2024
Assignee:
CRT Pioneer Fund LP
Inventors:
Julian S. Northen, John Mykytiuk, Gillian Moore
Abstract: Diphosphate salts of N2-(2-ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine, and crystalline forms thereof, processes for the preparation of the new salt forms; and their use as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer.
Type:
Grant
Filed:
June 6, 2019
Date of Patent:
April 2, 2024
Assignee:
CRT Pioneer Fund LP
Inventors:
Julian S. Northen, John Mykytiuk, Gillian Moore
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