Abstract: A sheathing for packaging a predetermined volume of a biological substance designed to be immersed in a liquid cryogenic agent, the sheathing including a thin tube and a ballast associated with the thin tube.

Abstract: The inventive device is provided with a unit (1) comprising a body (3) which interacts with a pipette tip (24) in a vertical position in order to retain the content of the pipette tip (24) in the unit (1) and comprises a nozzle (2) having a capillary channel (4) insertable into a straw (25) oriented in a transversal position with respect to the body in such a way that, when the body is in a vertical position, said nozzle (2) is in a horizontal position. The inventive method consists in sampling a liquid substance initially contained in a top-open container (45) with the aid of the pipette tip (24) in the vertical position, in transferring the content of pipette tip (24) to the body (3) of the unit (1) prior to filling the straw (25) with the predetermined dose of a liquid substance transferred thereto from the unit (1).

Abstract: The invention concerns an assembly for packaging a volume of substance to be preserved by cryogenic vitrification characterized in that it comprises a sheathing (2) including a thin tube (6) having a predetermined internal diameter (Di) and a predetermined length (L); a support (3) comprising a zone for receiving said predetermined volume, said support (3) capable of being introduced inside said thin tube (6); and a plunger (4) for pushing forward said support (3), said support (3) then taking up a predetermined position in said thin tube (6) with an interval between each end (21, 22) of said support (2) and the neighboring end (8, 9) of said thin tube (6).

Abstract: The invention relates to a packaging tube for a pre-determined volume of a biological substance to be stored at a low temperature and to a system including same. The inventive packaging tube comprises a portion (2) for receiving the volume and an annular end portion (3) designed to be more easily crushed by pinching than the receiving portion (2) and to adopt a flattened position in which two lips (30) are in contact with one another. In addition, the annular end portion (3) is designed such that the lips (30) are secured to one another in order to form a seal (31) on the tube. The system includes at least one such tube and a jaw welding device designed to move the annular portion (3) into the flattened position and to weld the lips (30) to one another in order to form the seal (31).

Abstract: The invention concerns an assembly for packaging a volume of substance to be preserved by cryogenic vitrification characterized in that it comprises a sheathing (2) including a thin tube (6) having a predetermined internal diameter (Di) and a predetermined length (L); a support (3) comprising a zone for receiving said predetermined volume, said support (3) capable of being introduced inside said thin tube (6); and a plunger (4) for pushing forward said support (3), said support (3) then taking up a predetermined position in said thin tube (6) with an interval between each end (21, 22) of said support (2) and the neighbouring end (8, 9) of said thin tube (6).