Patents Assigned to Cryopharm Corporation
  • Photoinactivation of viral and bacterial blood contaminants using halogenated coumarins
    Patent number: 5516629
    Abstract: A method for photoinactivating viral and/or bacterial contaminants in blood, blood products or cell cultures is presented. The blood, blood product or cell culture is mixed with an halogenated coumarin sensitizer and irradiated with UV light to inactivate the viral and/or bacterial contaminants.
    Type: Grant
    Filed: September 22, 1994
    Date of Patent: May 14, 1996
    Assignee: Cryopharm Corporation
    Inventors: Sang C. Park, Raymond P. Goodrich, Jr., Nagender Yerram, Samuel O. Sowemimo-Coker, Matthew S. Platz, Brian M. Aquila
  • Method of reconstituting lyophilized cells
    Patent number: 5425951
    Abstract: A process and medium are disclosed for the lyophilization of cells which comprises the use of solutions including monosaccharide hexoses and pentoses, and/or biocompatible amphipathic polymers to permit the reconstitution of viable cells.
    Type: Grant
    Filed: May 31, 1991
    Date of Patent: June 20, 1995
    Assignee: Cryopharm Corporation
    Inventors: Raymond P. Goodrich, Jr., Christine M. Williams
  • Method of inactivation of viral and bacterial blood contaminants
    Patent number: 5418130
    Abstract: A method is provided for inactivating viral and/or bacterial contamination in blood cellular matter, such as erythrocytes and platelets, or protein fractions. The cells or protein fractions are mixed with chemical sensitizers and irradiated with, for example, UV, visible, gamma or X-ray radiation. In particular, quaternary ammonium or phosphonium substituted, halo-psoralen compounds are described as being useful.
    Type: Grant
    Filed: July 13, 1993
    Date of Patent: May 23, 1995
    Assignee: Cryopharm Corporation
    Inventors: Matthew S. Platz, Raymond P. Goodrich, Jr., Nagendar Yerram
  • Method of inactivation of viral blood contaminants using acridine deriatives
    Patent number: 5342752
    Abstract: A method is provided for inactivating viral and/or bacterial and/or parasitic contamination in cellular blood matter or blood plasma protein fractions, using radiation sensitizing chemical compounds and irradiation with, for example, UV radiation.
    Type: Grant
    Filed: April 16, 1991
    Date of Patent: August 30, 1994
    Assignee: Cryopharm Corporation
    Inventors: Matthew S. Platz, Raymond P. Goodrich, Jr., Victoria A. Wong
  • Blood bag for lyophilization
    Patent number: 5257983
    Abstract: A lyophilization bag is provided in which a fluid, such as blood, may be introduced, lyophilized without collapsing the bag, stored, reconstituted and distributed from the bag without intermediate transfer of the useful contents from the bag.
    Type: Grant
    Filed: April 12, 1991
    Date of Patent: November 2, 1993
    Assignee: Cryopharm Corporation
    Inventors: Tina K. Garyantes, Daniel F. Jones, Hardin Gilbert, Miller Cho
  • Lyophilized and reconstituted blood platelet compositions
    Patent number: 5213814
    Abstract: A process and medium are disclosed for the lyophilization of cells, specifically platelets, and cell-like matter, which comprises the use of solutions including monosaccharide hexoses and pentoses, and biocompatible amphipathic polymers to permit the reconstitution of transfusably useful cells, specifically platelets, and cell-like matter.
    Type: Grant
    Filed: May 17, 1990
    Date of Patent: May 25, 1993
    Assignee: Cryopharm Corporation
    Inventors: Raymond P. Goodrich, Jr., Victoria A. Wong
  • Lyophilized and reconstituted red blood cell compositions
    Patent number: 5178884
    Abstract: A process and medium are disclosed for the lyophilization of red blood cells which comprises the use of solutions including monosaccharide hexoses and pentoses, and biocompatible amphipathic polymers to permit the reconstitution of viable red blood cells. Also disclosed are lyophilized and reconstituted erythrocyte and hemosome containing compositions.
    Type: Grant
    Filed: June 29, 1989
    Date of Patent: January 12, 1993
    Assignee: Cryopharm Corporation
    Inventors: Raymond P. Goodrich, Christine M. Williams, Roger W. Hackett
  • Medium for lyophilization of erythrocytes
    Patent number: 5171661
    Abstract: A process and medium are disclosed for the lyophilization of red blood cells which comprises the use of solutions including monosaccharide hexoses and pentoses, and/or biocompatible polymers to permit the reconstitution of viable red blood cells.
    Type: Grant
    Filed: July 31, 1990
    Date of Patent: December 15, 1992
    Assignee: Cryopharm Corporation
    Inventors: Raymond P. Goodrich, Jr., Christine M. Williams
  • Freezing and thawing of erythrocytes
    Patent number: 5153004
    Abstract: A process and medium are disclosed for the freezing of red blood cells which comprises the use of solutions including monosaccharide hexoses and pentoses, and/or biocompatible amphipathic polymers to permit the thawing without washing to produce viable red blood cells.
    Type: Grant
    Filed: April 5, 1990
    Date of Patent: October 6, 1992
    Assignee: Cryopharm Corporation
    Inventors: Raymond P. Goodrich, Jr., Christine M. Williams
  • Lyophilization of cells
    Patent number: 5045446
    Abstract: A process and medium are disclosed for the lyophilization of cells which comprises the use of solutions including monosaccharide hexoses and pentoses, and/or biocompatible amphipathic polymers to permit the reconstitution of viable cells.
    Type: Grant
    Filed: July 11, 1989
    Date of Patent: September 3, 1991
    Assignee: Cryopharm Corporation
    Inventors: Raymond P. Goodrich, Jr., Christine M. Williams
  • Lyophilized and reconstituted red blood cell and hemosome compositions
    Patent number: 5043261
    Abstract: A process and medium are disclosed for the lyophilization of red blood cells which comprises the use of solutions including monosaccharide hexoses and pentoses, and biocompatible polymers to permit the reconstitution of viable red blood cells.
    Type: Grant
    Filed: June 2, 1989
    Date of Patent: August 27, 1991
    Assignee: Cryopharm Corporation
    Inventors: Raymond Goodrich, Christine Williams
  • Lyophilization of red blood cells
    Patent number: 4874690
    Abstract: A process and medium are disclosed for the lyophilization of red blood cells which comprises the use of solutions including monosaccharide hexoses and pentoses, biocompatible polymers and polyanions to permit the reconstitution of viable red blood cells.
    Type: Grant
    Filed: August 26, 1988
    Date of Patent: October 17, 1989
    Assignee: Cryopharm Corporation
    Inventors: Raymond P. Goodrich, Jr., Christine M. Williams, Robert S. Franco, Murray Weiner