Patents Assigned to Cryoport, Inc.
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Patent number: 12638137Abstract: Systems and methods for monitoring environmental variables associated with temperature-sensitive products during shipping may include sensors attached to or inside a container being shipped and a remote processor receiving data provided by the sensors. For instance, temperature and orientation may be sensed over time and a status associated with a temperature-sensitive product may be determined based on the temperature and/or orientation and based on changes in the temperature and/or orientation over time. In this manner, potentially deleterious temperature and/or orientation excursions may be predicted and monitored.Type: GrantFiled: January 10, 2024Date of Patent: May 26, 2026Assignee: Cryoport, Inc.Inventors: Bret Bollinger, Amir Vahid, Ashish Misra, Chris Exline, Pratik Khetiya
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Patent number: 12631385Abstract: An adaptable immobilizer tray for use in a shipping container (e.g., a cryogenic shipping container) that can be configured to transition from a first configuration to a second configuration. The first configuration is configured to receive a payload of a first size, and the second configuration is configured to receive a payload of a second size, wherein the first size and the second size are different. The adaptable immobilizer tray can be adaptable to two or more payload sizes and configured to secure the payloads during transport of the shipping container.Type: GrantFiled: April 17, 2023Date of Patent: May 19, 2026Assignee: Cryoport, Inc.Inventors: James Wilbourn, Bobby Onel, Hugh Vu
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Patent number: 12630336Abstract: A temperature-controlled shipper may comprise a temperature-controlled enclosure, a tray, an outer enclosure, and a lid, wherein the tray may be securely coupled to the temperature-controlled enclosure to resist tampering with a payload located in the temperature-controlled enclosure. The secure coupling of the temperature-controlled enclosure and the tray may be achieved using securely fastened or attached loops on both the temperature-controlled enclosure and the tray, wherein each tamper-resistant tie is secured after looping through one loop on the temperature-controlled enclosure and one loop on the tray to prevent access to the payload.Type: GrantFiled: December 13, 2023Date of Patent: May 19, 2026Assignee: Cryoport, Inc.Inventors: Bobby Onel, James Wilbourn
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Patent number: 12616642Abstract: A cylindrical container for holding one or more articles, such as blood bags. The cylindrical container may hold multiple curved article containers comprising the one or more articles arranged in a circle. The cylindrical holding container may embody a carousel shape for easy access to the curved article containers. The ends of the multiple curved article containers may overlap each other to nest into the cylindrical holding container. The cylindrical holding containers may be stackable. The cylindrical holding container may be placed in a cryogenic shipper or dewar, to secure and stabilize the articles within during transport.Type: GrantFiled: July 12, 2023Date of Patent: May 5, 2026Assignee: Cryoport, Inc.Inventors: Bret Bollinger, Ben Lee
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Publication number: 20260097894Abstract: Hardened reusable shipping containers (e.g., shippers) are disclosed herein. A shipper may have a base enclosure that is configured to receive a payload and maintain a temperature of an environment surrounding the payload. The shipper may have various features such as bosses, compartments, and surface features to facilitate protection of a dewar inside the base enclosure, and retention of a payload during shipment. The shipper may have various features to facilitate ready stacking of shippers and suitability for use in air cargo operations.Type: ApplicationFiled: December 10, 2025Publication date: April 9, 2026Applicant: Cryoport, Inc.Inventors: James Wilbourn, Ben Lee, Mike Dybicz, Bobby Onel, David Nelson, Garrett Grommes
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Publication number: 20260063349Abstract: Devices, systems, and methods of trays for uniformly cooling a payload are provided. A tray includes a body. The body includes an internal wall, a plurality of side panels in connection with the internal wall panel and a plurality of dividers in connection with the internal wall panel and one or more of the plurality of side panels. The plurality of dividers may define a plurality of chambers, each chamber of the plurality of chambers at least partially bounded by a divider of the plurality of dividers and/or (ii) the internal wall panel. Each chamber of the plurality of chambers is configured to receive a portion of a cooling agent inserted into the body. A cover panel attached to the body.Type: ApplicationFiled: November 5, 2025Publication date: March 5, 2026Applicant: Cryoport, Inc.Inventors: Bret Bollinger, Ben Lee
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Publication number: 20260055852Abstract: A system, method and apparatus, and/or device is provided for securing a vapor plug on a cryogenic storage vessel. The vapor plug locking mechanism includes a vapor plug and a cryogenic storage vessel. The vapor plug has a first interlocking feature. The cryogenic storage vessel has an opening and a neck ring around the opening. The neck ring has a second interlocking feature. The first interlocking feature is configured to selectively overlap the second interlocking feature, wherein the two features selectably engage to retain the vapor plug to the cryogenic storage vessel.Type: ApplicationFiled: August 22, 2024Publication date: February 26, 2026Applicant: Cryoport, Inc.Inventors: David Nelson, James Wilbourn
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Publication number: 20260055948Abstract: Methods, systems, devices and/or apparatuses for a hardened reusable shipping container. The hardened reusable shipping container includes a lid. The lid is configured to be opened and closed. The hardened reusable shipping container includes a base enclosure. The base enclosure is coupled to the lid and has a payload area. The payload area is configured to receive a payload and maintain a temperature of an environment surrounding the payload. The hardened reusable shipping container includes an insert. The insert is configured to be positioned within the payload area to cool or maintain the temperature of the environment surrounding the payload.Type: ApplicationFiled: October 29, 2025Publication date: February 26, 2026Applicant: Cryoport, Inc.Inventors: Bret Bollinger, Eden Sanchez, Mike Dybicz, Bobby Onel, Ben Lee, Amanda Gessell, James Wilbourn, John Duval
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Publication number: 20260048932Abstract: In general, one aspect of the subject matter described in this specification is embodied in a rack system. The rack system includes a first stackable rack and a second stackable rack. The first stackable rack includes a top ceiling, a bottom surface, a first sidewall and a second sidewall. The second stackable rack includes a top ceiling, a bottom surface, a first sidewall, a second sidewall and a shelf. The top ceiling, the bottom surface, the first sidewall, the second sidewall and the shelf of the second stackable rack define a first compartment and a second compartment. The bottom surface of the first stackable rack is slidably coupled with the top ceiling of the second stackable rack.Type: ApplicationFiled: September 22, 2025Publication date: February 19, 2026Applicant: Cryoport, Inc.Inventors: Bobby Onel, Bret Bollinger, Ben Lee
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Patent number: 12510287Abstract: Devices, systems, and methods of trays for uniformly cooling a payload are provided. A tray includes a body. The body includes an internal wall, a plurality of side panels in connection with the internal wall panel and a plurality of dividers in connection with the internal wall panel and one or more of the plurality of side panels. The plurality of dividers may define a plurality of chambers, each chamber of the plurality of chambers at least partially bounded by a divider of the plurality of dividers and/or (ii) the internal wall panel. Each chamber of the plurality of chambers is configured to receive a portion of a cooling agent inserted into the body. A cover panel attached to the body.Type: GrantFiled: December 13, 2022Date of Patent: December 30, 2025Assignee: Cryoport, Inc.Inventors: Bret Bollinger, Ben Lee
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Publication number: 20250389391Abstract: Method, system, apparatus, and/or device for monitoring a shipment. The vapor plug system includes a vapor plug. The vapor plug fits onto a shipper and partially seals contents within a payload area of a shipper. The vapor plug system includes a sensor that is configured to measure or determine a condition or location of the shipper. The vapor plug system includes an electronic device that has a display. The display is configured to provide the condition or the location to a user. The vapor plug system includes a vapor plug adapter. The vapor plug adapter includes a recessed pocket that is configured to receive the electronic device. The vapor plug adapter includes an opening within the recessed pocket and is configured to receive the sensor and allow the sensor to be inserted into the payload area of the shipper.Type: ApplicationFiled: August 25, 2025Publication date: December 25, 2025Applicant: Cryoport, Inc.Inventors: Bret Bollinger, Ben Lee
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Publication number: 20250354658Abstract: Method, system, apparatus, and/or device for drying a dewar. The dewar drying apparatus includes a heating element. The heating element is configured to produce heat that warms a payload area within the dewar. The dewar drying apparatus includes a controller. The controller is coupled to the heating element and configured to determine or detect a temperature within the payload area of the dewar. The controller is configured to control, using the heating element, the temperature within the payload area of the dewar to evaporate a liquid or a gas within the payload area.Type: ApplicationFiled: August 1, 2025Publication date: November 20, 2025Applicant: Cryoport, Inc.Inventors: Eden Sanchez, Bret Bollinger, Ben Lee
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Publication number: 20250353659Abstract: A storage container is provided. The container may be insertable into a cold-storage dewar or other cold-storage container and may have multiple compartments. A payload item may be inserted into a tray and placed in one compartment for cold storage. Temperature buffering material may be inserted into one or more other compartment to provide for increased holding time at or near a desired temperature.Type: ApplicationFiled: July 25, 2025Publication date: November 20, 2025Applicant: Cryoport, Inc.Inventors: Bret Bollinger, Ben Lee
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Patent number: 12474104Abstract: Methods, systems, devices and/or apparatuses for a hardened reusable shipping container. The hardened reusable shipping container includes a lid. The lid is configured to be opened and closed. The hardened reusable shipping container includes a base enclosure. The base enclosure is coupled to the lid and has a payload area. The payload area is configured to receive a payload and maintain a temperature of an environment surrounding the payload. The hardened reusable shipping container includes an insert. The insert is configured to be positioned within the payload area to cool or maintain the temperature of the environment surrounding the payload.Type: GrantFiled: September 15, 2021Date of Patent: November 18, 2025Assignee: Cryoport, Inc.Inventors: Bret Bollinger, Eden Sanchez, Mike Dybicz, Bobby Onel, Ben Lee, Amanda Gessell, James Wilbourn, John Duval
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Patent number: 12448206Abstract: In general, one aspect of the subject matter described in this specification is embodied in a rack system. The rack system includes a first stackable rack and a second stackable rack. The first stackable rack includes a top ceiling, a bottom surface, a first sidewall and a second sidewall. The second stackable rack includes a top ceiling, a bottom surface, a first sidewall, a second sidewall and a shelf. The top ceiling, the bottom surface, the first sidewall, the second sidewall and the shelf of the second stackable rack define a first compartment and a second compartment. The bottom surface of the first stackable rack is slidably coupled with the top ceiling of the second stackable rack.Type: GrantFiled: June 29, 2021Date of Patent: October 21, 2025Assignee: Cryoport, Inc.Inventors: Bobby Onel, Bret Bollinger, Ben Lee
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Patent number: 12435839Abstract: Method, system, apparatus, and/or device for monitoring a shipment. The vapor plug system includes a vapor plug. The vapor plug fits onto a shipper and partially seals contents within a payload area of a shipper. The vapor plug system includes a sensor that is configured to measure or determine a condition or location of the shipper. The vapor plug system includes an electronic device that has a display. The display is configured to provide the condition or the location to a user. The vapor plug system includes a vapor plug adapter. The vapor plug adapter includes a recessed pocket that is configured to receive the electronic device. The vapor plug adapter includes an opening within the recessed pocket and is configured to receive the sensor and allow the sensor to be inserted into the payload area of the shipper.Type: GrantFiled: February 21, 2025Date of Patent: October 7, 2025Assignee: Cryoport, Inc.Inventors: Bret Bollinger, Ben Lee
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Publication number: 20250304320Abstract: Hardened reusable shipping containers (e.g., shippers) are disclosed herein. A shipper may have a base enclosure that is configured to receive a payload and maintain a temperature of an environment surrounding the payload. The shipper may have various features such as bosses, compartments, and surface features to facilitate protection of a dewar inside the base enclosure, and retention of a payload during shipment. The shipper may have various features to facilitate ready stacking of shippers and suitability for use in air cargo operations.Type: ApplicationFiled: March 19, 2025Publication date: October 2, 2025Applicant: Cryoport, Inc.Inventors: James Wilbourn, David Nelson, Garrett Grommes, Mike Dybicz, Bobby Onel
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Patent number: 12383465Abstract: An envelope is configured to hold, support, and protect an article such as a blood bag during transportation under fic temperatures. The envelope includes a single piece component (e.g., a monolithic component), including multiple panels that are configured to fold to form an enclosure that surrounds the article such as the blood bag for support and protection of the article such as the blood bag.Type: GrantFiled: June 29, 2022Date of Patent: August 12, 2025Assignee: Cryoport, Inc.Inventors: Steffen Smith, Mike Dybicz, Brittany Roberts, Bobby Onel
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Patent number: 12379071Abstract: Method, system, apparatus, and/or device for drying a dewar. The dewar drying apparatus includes a heating element. The heating element is configured to produce heat that warms a payload area within the dewar. The dewar drying apparatus includes a controller. The controller is coupled to the heating element and configured to determine or detect a temperature within the payload area of the dewar. The controller is configured to control, using the heating element, the temperature within the payload area of the dewar to evaporate a liquid or a gas within the payload area.Type: GrantFiled: July 22, 2020Date of Patent: August 5, 2025Assignee: Cryoport, Inc.Inventors: Eden Sanchez, Bret Bollinger, Ben Lee
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Publication number: 20250228344Abstract: A carrying bag for transporting biomaterials can comprise a plurality of pockets. Each of the plurality of pockets can be coupled to an adjacent of the plurality of pockets. Based on a configuration of the plurality of pockets, an interstitial void of flexible dimension can be disposed between adjacent pockets in the plurality of pockets. The interstitial void of flexible dimension can facilitate an open configuration that allows an opening for each pocket to converge into a respective cavity of that pocket.Type: ApplicationFiled: March 12, 2025Publication date: July 17, 2025Applicant: Cryoport, Inc.Inventors: Mike Dybicz, Bobby Onel, Brittany Roberts, Steffen Smith