Patents Assigned to CRYOTHERAPEUTICS GMBH
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Patent number: 11819452Abstract: A catheter is provided comprising a flexible heat transfer element provided on an outer surface of the catheter, a conduit arranged to supply an inflation fluid for inflating the flexible heat transfer element so as to form an inflated balloon, a guide wire lumen for receiving a guide wire, and an elongate cooling element arranged to cool said inflation fluid for inflating the balloon. Said cooling element and said guide wire lumen are arranged inside the flexible heat transfer element such that, when inflated the cooling element is substantially central within the balloon and said guide wire lumen is parallel to and radially offset from the cooling element.Type: GrantFiled: March 8, 2021Date of Patent: November 21, 2023Assignee: CRYOTHERAPEUTICS GMBHInventors: Peter Kyone Park, Domenic Santoianni, Stewart Maddison Fox, Peter Georg Laitenberger
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Patent number: 11116560Abstract: A catheter is provided comprising a flexible heat transfer element provided on an outer surface of the catheter. The catheter further comprises a conduit arranged to supply an inflation fluid for inflating the flexible heat transfer element so as to form an inflated balloon, and a plurality of cooling elements arranged to cool the inflation fluid for inflating the balloon. Each cooling element comprises a first tube provided inside a second tube, wherein the first tube is substantially parallel to the second tube. The second tube is configured to receive a flow of a coolant for cooling the cooling element from the first tube.Type: GrantFiled: November 16, 2016Date of Patent: September 14, 2021Assignee: Cryotherapeutics GmbHInventors: Maurice Buchbinder, Stewart M. Fox, Domenic Santoianni, Peter Kyone Park
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Patent number: 10940036Abstract: A catheter is provided comprising a flexible heat transfer element provided on an outer surface of the catheter, a conduit arranged to supply an inflation fluid for inflating the flexible heat transfer element so as to form an inflated balloon, a guide wire lumen for receiving a guide wire, and an elongate cooling element arranged to cool said inflation fluid for inflating the balloon. Said cooling element and said guide wire lumen are arranged inside the flexible heat transfer element such that, when inflated the cooling element is substantially central within the balloon and said guide wire lumen is parallel to and radially offset from the cooling element.Type: GrantFiled: May 9, 2017Date of Patent: March 9, 2021Assignee: Cryotherapeutics GmbHInventors: Peter Kyone Park, Dominic Santoianni, Stewart Maddison Fox, Peter Georg Laitenberger
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Patent number: 10646265Abstract: Disclosed herein is an apparatus for cooling a sterile liquid for use in cryotherapy, the apparatus comprising: a first chamber (202) adapted to receive a removable container (201) of sterile liquid and a fluid port for receiving a fluid for applying, in use, pressure to a received removable container (201); and a second chamber (203) comprising a cooler; wherein the first chamber (202) is arranged to be in thermal conductivity with the second chamber (203) such that, in use, the contents of the first chamber (202) are cooled by the cooler of the second chamber (203). Advantageously, embodiments provide a system, heat exchanger unit within the system and method for supplying a sterilised working fluid to a catheter system for cryotherapy, the working fluid being supplied at a desired and easily controllable temperature and flow rate.Type: GrantFiled: December 15, 2014Date of Patent: May 12, 2020Assignee: Cryotherapeutics GmbHInventors: Stuart Robert Abercrombie, Duncan Aleck Bishop, Symon Cotton, Richard Day, Sylvain Bruno Jamais, Simon Karger, Andrew Lintott, Nathan Wrench
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Publication number: 20190209368Abstract: A catheter is provided comprising a flexible heat transfer element provided on an outer surface of the catheter, a conduit arranged to supply an inflation fluid for inflating the flexible heat transfer element so as to form an inflated balloon, a guide wire lumen for receiving a guide wire, and an elongate cooling element arranged to cool said inflation fluid for inflating the balloon. Said cooling element and said guide wire lumen are arranged inside the flexible heat transfer element such that, when inflated the cooling element is substantially central within the balloon and said guide wire lumen is parallel to and radially offset from the cooling element.Type: ApplicationFiled: May 9, 2017Publication date: July 11, 2019Applicant: Cryotherapeutics GmbHInventors: Peter Kyone PARK, Dominic SANTOIANNI, Stewart Maddison FOX, Peter Georg LAITENBERGER
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Publication number: 20160361106Abstract: Disclosed herein is an apparatus for cooling a sterile liquid for use in cryotherapy, the apparatus comprising: a first chamber (202) adapted to receive a removable container (201) of sterile liquid and a fluid port for receiving a fluid for applying, in use, pressure to a received removable container (201); and a second chamber (203) comprising a cooler; wherein the first chamber (202) is arranged to be in thermal conductivity with the second chamber (203) such that, in use, the contents of the first chamber (202) are cooled by the cooler of the second chamber (203). Advantageously, embodiments provide a system, heat exchanger unit within the system and method for supplying a sterilised working fluid to a catheter system for cryotherapy, the working fluid being supplied at a desired and easily controllable temperature and flow rate.Type: ApplicationFiled: December 15, 2014Publication date: December 15, 2016Applicant: CRYOTHERAPEUTICS GMBHInventors: Stuart Robert Abercrombie, Duncan Aleck Bishop, Symon Cotton, Richard Day, Sylvain Bruno Jamais, Simon Karger, Andrew Lintott, Nathan Wrench
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Patent number: 9283021Abstract: There is provided a method of supplying cryoenergy to a plaque within a blood vessel. The method comprises expanding an expandable membrane of a catheter apparatus with a pressure of less than 5 ATM (507 kPa), the catheter apparatus having been placed in thermal contact with the plaque within the blood vessel. The method also comprises establishing a temperature of between +15° C. (288K) and ?35° C. (238K) at an interface of the expandable membrane and the blood vessel. A system and catheter apparatus are also provided.Type: GrantFiled: January 20, 2015Date of Patent: March 15, 2016Assignee: Cryotherapeutics GmbHInventors: Maurice Buchbinder, Randell Louis Werneth, Yiannakis Petrou Yianni, J. Christopher Flaherty, Daniel Nahon, Domenic Santoianni
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Patent number: 8968282Abstract: There is provided a method of supplying cryoenergy to a plaque within a blood vessel. The method comprises expanding an expandable membrane of a catheter apparatus with a pressure of less than 5 ATM (507 kPa), the catheter apparatus having been placed in thermal contact with the plaque within the blood vessel. The method also comprises establishing a temperature of between +15° C. (288K) and ?35° C. (238K) at an interface of the expandable membrane and the blood vessel. A system and catheter apparatus are also provided.Type: GrantFiled: April 13, 2012Date of Patent: March 3, 2015Assignee: Cryotherapeutics GmbHInventors: Maurice Buchbinder, Randell Louis Werneth, Yiannakis Petrou Yianni, Daniel Nahon, J. Christopher Flaherty, Domenic Santoianni
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Publication number: 20120265188Abstract: There is provided a method of supplying cryoenergy to a plaque within a blood vessel. The method comprises expanding an expandable membrane of a catheter apparatus with a pressure of less than 5 ATM (507 kPa), the catheter apparatus having been placed in thermal contact with the plaque within the blood vessel. The method also comprises establishing a temperature of between +15° C. (288K) and ?35° C. (238K) at an interface of the expandable membrane and the blood vessel. A system and catheter apparatus are also provided.Type: ApplicationFiled: April 13, 2012Publication date: October 18, 2012Applicant: CRYOTHERAPEUTICS GMBHInventors: Maurice Buchbinder, Randell Louis Werneth, Yiannakis Petrou Yianni, Daniel Nahon, J. Christopher Flaherty, Domenic Santoianni