Abstract: A vapor dispensation system includes a base having a vaporizing element, a cylindrical vapor tube extending along a longitudinal axis, a mouthpiece connected to the vapor tube opposite the base, a vial body surrounding the vapor tube from the base to the mouthpiece, and a cartridge dimensioned to fit within the vial body. The cartridge has a frangible seal ruptured by the seal penetrating element when the cartridge is enclosed in the vial body between the mouthpiece and base. A method of filling a vapor dispensation system includes disengaging a mouthpiece, removing a spent cartridge, inserting a fluid containing cartridge with a frangible seal of the cartridge oriented toward the vapor dispensation system, rupturing the frangible seal upon full insertion, and engaging the mouthpiece onto the longitudinal end of a vapor dispensation system.