Patents Assigned to CSL Behring AG
  • Publication number: 20250025554
    Abstract: The present invention pertains to a pharmaceutical product comprising a polyclonal immunoglobulin solution in a pre-filled polymer syringe in secondary packaging comprising an oxygen scavenger.
    Type: Application
    Filed: October 9, 2024
    Publication date: January 23, 2025
    Applicant: CSL Behring AG
    Inventors: Renzo PEDRUSSIO, Regula STYGER
  • Patent number: 12194101
    Abstract: The present invention relates to the use of proline for reducing the viscosity of a protein preparation.
    Type: Grant
    Filed: October 29, 2021
    Date of Patent: January 14, 2025
    Assignee: CSL Behring AG
    Inventors: Reinhard Franz Bolli, Werner Maeder, Peter Lerch
  • Patent number: 12144861
    Abstract: The present invention pertains to a pharmaceutical product comprising a polyclonal immunoglobulin solution in a pre-filled polymer syringe in secondary packaging comprising an oxygen scavenger.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: November 19, 2024
    Assignee: CSL Behring AG
    Inventors: Renzo Pedrussio, Regula Styger
  • Publication number: 20240336650
    Abstract: The invention relates to a method for the purification of immunoglobulin and/or albumin from a sample of plasma, the method comprising mixing a sample of plasma with a medium chain fatty acid, and recovering the soluble immunoglobulin from the mixture.
    Type: Application
    Filed: May 26, 2022
    Publication date: October 10, 2024
    Applicant: CSL Behring AG
    Inventor: Ibrahim EL MENYAWI
  • Publication number: 20230083398
    Abstract: The present invention relates to an immunoglobulin preparation comprising immunoglobulin in a mass-volume percentage of at least 4%, wherein the concentration of oxygen dissolved in the preparation at room temperature is less than 40 ?mol/l.
    Type: Application
    Filed: July 14, 2022
    Publication date: March 16, 2023
    Applicant: CSL Behring AG
    Inventors: Werner Maeder, Reinhard Franz Bolli, Peter Lerch, Renzo Pedrussio, Liane Hoefferer
  • Patent number: 11419936
    Abstract: The present invention relates to an immunoglobulin preparation comprising immunoglobulin in a mass-volume percentage of at least 4%, wherein the concentration of oxygen dissolved in the preparation at room temperature is less than 40 ?mol/l.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: August 23, 2022
    Assignee: CSL Behring AG
    Inventors: Werner Maeder, Reinhard Franz Bolli, Peter Lerch, Renzo Pedrussio, Liane Hoefferer
  • Publication number: 20220118092
    Abstract: The present invention relates to the use of proline for reducing the viscosity of a protein preparation.
    Type: Application
    Filed: October 29, 2021
    Publication date: April 21, 2022
    Applicant: CSL Behring AG
    Inventors: Reinhard Franz Bolli, Werner Maeder, Peter Lerch
  • Publication number: 20200054748
    Abstract: The present invention relates to an immunoglobulin preparation comprising immunoglobulin in a mass-volume percentage of at least 4%, wherein the concentration of oxygen dissolved in the preparation at room temperature is less than 40 ?mol/l.
    Type: Application
    Filed: August 27, 2019
    Publication date: February 20, 2020
    Applicant: CSL Behring AG
    Inventors: Werner Maeder, Reinhard Franz Bolli, Peter Lerch, Renzo Pedrussio, Liane Hoefferer
  • Patent number: 10434176
    Abstract: The present invention relates to an immunoglobulin preparation comprising immunoglobulin in a mass-volume percentage of at least 4%, wherein the concentration of oxygen dissolved in the preparation at room temperature is less than 40 ?mol/l.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: October 8, 2019
    Assignee: CSL Behring AG
    Inventors: Werner Maeder, Reinhard Franz Bolli, Peter Lerch, Renzo Pedrussio, Liane Hoefferer
  • Publication number: 20180360969
    Abstract: The present invention relates to the use of proline for reducing the viscosity of a protein preparation.
    Type: Application
    Filed: June 15, 2018
    Publication date: December 20, 2018
    Applicant: CSL Behring AG
    Inventors: Reinhard Franz Bolli, Werner Maeder, Peter Lerch
  • Patent number: 10137197
    Abstract: The present invention relates to the use of proline for reducing the viscosity of a protein preparation.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: November 27, 2018
    Assignee: CSL Behring AG
    Inventors: Reinhard Franz Bolli, Werner Maeder, Peter Lerch
  • Patent number: 9937229
    Abstract: The present invention relates generally to a method of purifying proteins. More specifically, the present inventions relates to a method of purifying haptoglobin and hemopexin from the same starting material, and uses thereof.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: April 10, 2018
    Assignee: CSL Behring AG
    Inventor: Nathan Brinkman
  • Publication number: 20170014509
    Abstract: The present invention relates to an immunoglobulin preparation comprising immunoglobulin in a mass-volume percentage of at least 4%, wherein the concentration of oxygen dissolved in the preparation at room temperature is less than 40 ?mol/l.
    Type: Application
    Filed: July 15, 2016
    Publication date: January 19, 2017
    Applicant: CSL Behring AG
    Inventors: Werner Maeder, Reinhard Franz Bolli, Peter Lerch, Renzo Pedrussio, Liane Hoefferer
  • Patent number: 9546209
    Abstract: The invention relates to compositions comprising immunoglobulin for use in the treatment of mucositis by topical application. In particular, the invention relates to compositions comprising J chain-containing IgA and secretory component for the treatment of mucositis.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: January 17, 2017
    Assignees: CSL Behring AG, Universitaet Bern
    Inventors: Christoph Aebi, Sonja Christina Lueer, Alexander Schaub, Sylvia Miescher, Adrian Zuercher, Cédric Pierre Vonarburg
  • Patent number: 9534029
    Abstract: The present invention relates generally to a method of purifying proteins. More specifically, the present inventions relates to a method of purifying haptoglobin and hemopexin from the same starting material, and uses thereof.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: January 3, 2017
    Assignee: CSL Behring AG
    Inventor: Nathan Brinkman
  • Patent number: 9422364
    Abstract: The present invention relates to an immunoglobulin preparation comprising immunoglobulin in a mass-volume percentage of at least 4%, wherein the concentration of oxygen dissolved in the preparation at room temperature is less than 40 ?mol/l.
    Type: Grant
    Filed: February 24, 2011
    Date of Patent: August 23, 2016
    Assignee: CSL Behring AG
    Inventors: Werner Maeder, Reinhard Franz Bolli, Peter Lerch, Renzo Pedrussio, Liane Hoefferer
  • Publication number: 20160151495
    Abstract: The present invention relates to the use of proline for reducing the viscosity of a protein preparation.
    Type: Application
    Filed: December 15, 2015
    Publication date: June 2, 2016
    Applicant: CSL Behring AG
    Inventors: Reinhard Franz Bolli, Werner Maeder, Peter Lerch
  • Publication number: 20150005476
    Abstract: The invention relates to a process for enriching IgA (and IgM) from IgA-comprising material. In particular, it relates to a sequential elution process of an anion exchanger that leads to an advantageous enrichment and separation of monomeric and dimeric IgA.
    Type: Application
    Filed: March 8, 2013
    Publication date: January 1, 2015
    Applicant: CSL Behring AG
    Inventors: Ibrahim El Menyawi, Marius Loetscher, Doreen Siegemund
  • Patent number: 8715652
    Abstract: The present invention relates to a protein preparation having increased stability, comprising a stabiliser selected from the group consisting of non-polar and basic amino acids and having a pH of 4.0 to 5.2. The invention further relates to a pharmaceutical composition and a method of stabilising protein preparations.
    Type: Grant
    Filed: November 17, 2004
    Date of Patent: May 6, 2014
    Assignee: CSL Behring AG
    Inventors: Reinhard Bolli, Gerhard Hodler, Regula Styger
  • Patent number: 8632773
    Abstract: The present invention relates to a population of antibodies enriched from an antibody preparation, wherein the enriched population of antibodies has an altered amount of sialylation in the Fab region of the antibodies as compared to the antibody preparation prior to enrichment. Furthermore, the present invention relates to a method of enriching a population of antibodies from an antibody preparation, wherein the enriched population of antibodies has an altered amount of sialylation in the Fab region of the antibodies as compared to the antibody preparation prior to enrichment. The present invention also relates to the population of antibodies of the invention for use in medicine, a pharmaceutical composition comprising the populations of antibodies of the invention and the use of the population of antibodies of the invention in the prevention and/or treatment of atherosclerosis, cancer and infections such as bacterial, viral or fungal infections.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: January 21, 2014
    Assignees: CSL Behring AG, University of Washington
    Inventors: Fabian Käsermann, Monika Rüegsegger, Sylvia Miescher, Keith Elkon