Abstract: The present invention pertains to a pharmaceutical product comprising a polyclonal immunoglobulin solution in a pre-filled polymer syringe in secondary packaging comprising an oxygen scavenger.
Abstract: The present invention pertains to a pharmaceutical product comprising a polyclonal immunoglobulin solution in a pre-filled polymer syringe in secondary packaging comprising an oxygen scavenger.
Abstract: The invention relates to a method for the purification of immunoglobulin and/or albumin from a sample of plasma, the method comprising mixing a sample of plasma with a medium chain fatty acid, and recovering the soluble immunoglobulin from the mixture.
Abstract: The present invention relates to an immunoglobulin preparation comprising immunoglobulin in a mass-volume percentage of at least 4%, wherein the concentration of oxygen dissolved in the preparation at room temperature is less than 40 ?mol/l.
Type:
Application
Filed:
July 14, 2022
Publication date:
March 16, 2023
Applicant:
CSL Behring AG
Inventors:
Werner Maeder, Reinhard Franz Bolli, Peter Lerch, Renzo Pedrussio, Liane Hoefferer
Abstract: The present invention relates to an immunoglobulin preparation comprising immunoglobulin in a mass-volume percentage of at least 4%, wherein the concentration of oxygen dissolved in the preparation at room temperature is less than 40 ?mol/l.
Type:
Grant
Filed:
August 27, 2019
Date of Patent:
August 23, 2022
Assignee:
CSL Behring AG
Inventors:
Werner Maeder, Reinhard Franz Bolli, Peter Lerch, Renzo Pedrussio, Liane Hoefferer
Abstract: The present invention relates to an immunoglobulin preparation comprising immunoglobulin in a mass-volume percentage of at least 4%, wherein the concentration of oxygen dissolved in the preparation at room temperature is less than 40 ?mol/l.
Type:
Application
Filed:
August 27, 2019
Publication date:
February 20, 2020
Applicant:
CSL Behring AG
Inventors:
Werner Maeder, Reinhard Franz Bolli, Peter Lerch, Renzo Pedrussio, Liane Hoefferer
Abstract: The present invention relates to an immunoglobulin preparation comprising immunoglobulin in a mass-volume percentage of at least 4%, wherein the concentration of oxygen dissolved in the preparation at room temperature is less than 40 ?mol/l.
Type:
Grant
Filed:
July 15, 2016
Date of Patent:
October 8, 2019
Assignee:
CSL Behring AG
Inventors:
Werner Maeder, Reinhard Franz Bolli, Peter Lerch, Renzo Pedrussio, Liane Hoefferer
Abstract: The present invention relates generally to a method of purifying proteins. More specifically, the present inventions relates to a method of purifying haptoglobin and hemopexin from the same starting material, and uses thereof.
Abstract: The present invention relates to an immunoglobulin preparation comprising immunoglobulin in a mass-volume percentage of at least 4%, wherein the concentration of oxygen dissolved in the preparation at room temperature is less than 40 ?mol/l.
Type:
Application
Filed:
July 15, 2016
Publication date:
January 19, 2017
Applicant:
CSL Behring AG
Inventors:
Werner Maeder, Reinhard Franz Bolli, Peter Lerch, Renzo Pedrussio, Liane Hoefferer
Abstract: The invention relates to compositions comprising immunoglobulin for use in the treatment of mucositis by topical application. In particular, the invention relates to compositions comprising J chain-containing IgA and secretory component for the treatment of mucositis.
Type:
Grant
Filed:
March 8, 2013
Date of Patent:
January 17, 2017
Assignees:
CSL Behring AG, Universitaet Bern
Inventors:
Christoph Aebi, Sonja Christina Lueer, Alexander Schaub, Sylvia Miescher, Adrian Zuercher, Cédric Pierre Vonarburg
Abstract: The present invention relates generally to a method of purifying proteins. More specifically, the present inventions relates to a method of purifying haptoglobin and hemopexin from the same starting material, and uses thereof.
Abstract: The present invention relates to an immunoglobulin preparation comprising immunoglobulin in a mass-volume percentage of at least 4%, wherein the concentration of oxygen dissolved in the preparation at room temperature is less than 40 ?mol/l.
Type:
Grant
Filed:
February 24, 2011
Date of Patent:
August 23, 2016
Assignee:
CSL Behring AG
Inventors:
Werner Maeder, Reinhard Franz Bolli, Peter Lerch, Renzo Pedrussio, Liane Hoefferer
Abstract: The invention relates to a process for enriching IgA (and IgM) from IgA-comprising material. In particular, it relates to a sequential elution process of an anion exchanger that leads to an advantageous enrichment and separation of monomeric and dimeric IgA.
Type:
Application
Filed:
March 8, 2013
Publication date:
January 1, 2015
Applicant:
CSL Behring AG
Inventors:
Ibrahim El Menyawi, Marius Loetscher, Doreen Siegemund
Abstract: The present invention relates to a protein preparation having increased stability, comprising a stabiliser selected from the group consisting of non-polar and basic amino acids and having a pH of 4.0 to 5.2. The invention further relates to a pharmaceutical composition and a method of stabilising protein preparations.
Type:
Grant
Filed:
November 17, 2004
Date of Patent:
May 6, 2014
Assignee:
CSL Behring AG
Inventors:
Reinhard Bolli, Gerhard Hodler, Regula Styger
Abstract: The present invention relates to a population of antibodies enriched from an antibody preparation, wherein the enriched population of antibodies has an altered amount of sialylation in the Fab region of the antibodies as compared to the antibody preparation prior to enrichment. Furthermore, the present invention relates to a method of enriching a population of antibodies from an antibody preparation, wherein the enriched population of antibodies has an altered amount of sialylation in the Fab region of the antibodies as compared to the antibody preparation prior to enrichment. The present invention also relates to the population of antibodies of the invention for use in medicine, a pharmaceutical composition comprising the populations of antibodies of the invention and the use of the population of antibodies of the invention in the prevention and/or treatment of atherosclerosis, cancer and infections such as bacterial, viral or fungal infections.
Type:
Grant
Filed:
March 26, 2010
Date of Patent:
January 21, 2014
Assignees:
CSL Behring AG, University of Washington
Inventors:
Fabian Käsermann, Monika Rüegsegger, Sylvia Miescher, Keith Elkon