Patents Assigned to CSPC NBP Pharmaceutical Co., Ltd.
  • Patent number: 8609137
    Abstract: The present invention discloses a novel soft capsule of butylphthalide and a process for preparing the same. The soft capsule of butylphthalide is composed of a capsule wall material and a drug-containing oil, wherein the drug-containing oil is essentially composed of butylphthalide and a vegetable oil as the diluent in a weight ratio of about 1:0˜10. The capsule wall material is composed of a capsule wall matrix, a plasticizer and water in a weight ratio of 1:0.2˜0.4:0.8˜1.3. The soft capsule of butylphthalide described in the present invention can mask the strong and special flavor of butylphthalide, and overcome the difficulties associated with formulating oily active ingredient into other oral formulation. The disintegration time of the soft capsule satisfies the requirement of Pharmacopoeia of P.R. China.
    Type: Grant
    Filed: April 22, 2011
    Date of Patent: December 17, 2013
    Assignees: CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd., CSPC NBP Pharmaceutical Co., Ltd.
    Inventors: Jianqing Li, Min Bai, Wenmin Guo, Surui Chen, Liyun Liu, Guirong Zhou