Patents Assigned to CTI, Inc.
  • Publication number: 20050084055
    Abstract: An apparatus for containing and cooling enriched water for the production of activated fluorine (18F). A target assembly is fabricated with internal cooling channels having minimal conduction paths and high Reynolds number flows. In one embodiment, the target assembly is fabricated of tantalum, which has superior oxidation resistance over silver. The superior oxidation resistance and increased cooling capacity allows for high beam currents.
    Type: Application
    Filed: September 25, 2003
    Publication date: April 21, 2005
    Applicant: CTI, Inc.
    Inventors: Charles Alvord, Andy Williamson
  • Publication number: 20040022696
    Abstract: A method of producing multiple batches of a radiopharmaceutical, such as FDG. The method includes the steps of transferring the appropriate liquids to a production apparatus, processing the liquids to produce the radiopharmaceutical, delivering the radiopharmaceutical to a container, automatically cleaning the apparatus, and repeating the previous steps, as desired. The apparatus for multi-batch production of FDG includes a reagent delivery system, a reaction vessel, a filter assembly, and a control system. The combination of these components provides a method that is capable of producing multiple batches of a radiopharmaceutical with minimal operator intervention and, consequently, minimal radiation exposure.
    Type: Application
    Filed: April 23, 2003
    Publication date: February 5, 2004
    Applicant: CTI, Inc.
    Inventors: Steven S. Zigler, Joseph C. Matteo, Thomas Mangner
  • Patent number: 6599484
    Abstract: An apparatus for processing radionuclides which generally includes a reaction vessel and a block. The reaction vessel includes a test tube and a cover secured to a top portion of the test tube. The cover defines at least one opening for receiving an input tube therethrough such that raw materials, reagents, gases and products can be introduced into or removed from the test tube. The block defines a vessel receptacle, an upper temperature changing means and a lower temperature changing means. The vessel receptacle defines an upper zone and a lower zone and is configured to receive the reaction vessel therein in a manner such that an upper zone space is defined between an exterior of the reaction vessel and an inner wall of the vessel receptacle in the upper zone. Likewise, a lower zone space is defined between an exterior of the reaction vessel and inner wall of the vessel receptacle in the lower zone.
    Type: Grant
    Filed: May 12, 2000
    Date of Patent: July 29, 2003
    Assignee: CTI, Inc.
    Inventors: Steven S. Zigler, Thomas Mangner, Joseph C. Matteo
  • Patent number: 6449331
    Abstract: A combined positron emission tomography (PET) and computed tomography (CT) detector mounted on a single support on the same gantry of a combined PET and CT scanner. The common detector includes an array of scintillator crystals or pixels with each pixel mated to a photodetector. The photodetector is connected to discrete event circuitry, which provides discrete event information to the combined PET and CT scanner. Also, the photodetector is connected to integrating circuitry, which provides integrated count rate information to the CT scanner when the discrete event information is not adequate. By using a common detector, the registration of the PET image with the CT image is improved, less components are mounted on the gantry, the overall size of the gantry is reduced, resulting in a shorter tunnel and less rotating mass, and CT performance is enhanced by providing means for selecting the energy level of the x-rays to be detected.
    Type: Grant
    Filed: January 9, 2001
    Date of Patent: September 10, 2002
    Assignee: CTI, Inc.
    Inventors: Robert E. Nutt, Ronald Nutt
  • Patent number: 6413311
    Abstract: A Cerium-Doped Lutetium Oxyorthosilicate scintillator boule having a graded decay time. The method for manufacturing an LSO:Ce crystal boule having a decay time gradient decreasing from the top end to the bottom end first includes the step selecting an iridium crucible. The crucible is selected based upon its diameter relative to the diameter defined by said crystal boule. The crucible is also selected based upon its volume relative to the volume of the crystal boule to be grown. A Cerium dopant (CeO2) is added to a mixture of Lutetium Oxide (Lu2O3) and Silicon Dioxide (SiO2). The composition is heated until melted to define a melt. A seed crystal is then placed in contact with the melt, is rotated, and slowly withdrawn, thereby yielding an LSO:Ce crystal boule defining a decay time gradient.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: July 2, 2002
    Assignee: CTI, Inc.
    Inventors: Charles L. Melcher, Ronald Nutt, Michael E. Casey
  • Patent number: 6368137
    Abstract: A chip carrying socket includes a base and at least one and preferably two cam shafts journaled or supported within the base in a spaced relationship for rotational movement relative to the base. A plate is supported upon the base and extends between the cam shafts. The plate has a plurality of openings formed therein which receive the leads of an IC. In a BGA type IC, these leads are semi-spherical balls which depend from the lower face of the IC. Conductors or pins adapted for connection to testing or operative circuitry are carried by the base and extend into proximity with the leads of the IC as it is supported upon the plate. Each cam shaft engages the plate so as to shift the plate relative to the base causing the conductors carried by the base to forcibly engage the leads of the IC when in one shifted position and causing the conductors to be released from such forcible engagement with the leads of the IC when in a second shifted position.
    Type: Grant
    Filed: September 23, 1999
    Date of Patent: April 9, 2002
    Assignee: Wells-CTI, Inc.
    Inventor: Erik G. Orwoll
  • Patent number: 6359952
    Abstract: A target grid assembly for employment in a target assembly used to produce radioisotopes by bombarding a target material contained in the target assembly with a particle beam. The target assembly includes the target grid assembly, the target window and a target body enclosed in a target housing. The target body defines a target reservoir for receiving the target material and the target window serves to seal the target reservoir. The target grid assembly includes a vacuum window and a target grid. The target grid defines a target grid portion, a helium input and a helium output. The target grid portion defines a plurality of target grid supports which are configured to form a plurality of target grid oblong openings. The vacuum window is supported against the upstream side of the target grid portion and the target window is supported between the downstream side and the target body.
    Type: Grant
    Filed: February 24, 2000
    Date of Patent: March 19, 2002
    Assignee: CTI, Inc.
    Inventor: C. William Alvord
  • Patent number: 6342688
    Abstract: A method of preparing an iridium crucible for crystal growth. As a form of preventive maintenance or during a repair, an iridium crucible is prepared by a method of surface conditioning by way of weld puddling the entire surface of the bottom or on the sidewalls from the bottom up to a height sufficient to include the depth of the residual crystal material after pulling of a crystal or both. In this regard, the surface of the iridium crucible is pulse welded so as to puddle a small portion of the surface without penetrating the side or bottom wall. In the preferred embodiment, the entire surface of the bottom of the iridium crucible is conditioned by weld melting. Similarly, the sidewalls are similarly conditioned by way of weld puddling such as by a pulsating welder. It will be recognized that any state of the art welding apparatus, such as a GTAW welder, TIG welder, laser welder or the like, that generates temperatures sufficient to melt iridium while controlling the depth of penetration can be utilized.
    Type: Grant
    Filed: June 9, 2000
    Date of Patent: January 29, 2002
    Assignee: CTI, Inc.
    Inventor: John T. Israel
  • Patent number: 6328027
    Abstract: A method for precision cutting liquid soluble scintillator materials by an operator is disclosed, including the steps of providing a first run of a moving filament in operative proximity to cut the scintillator materials, concurrent with wetting at least the first run length of the moving filament with organic solvent, and engaging the wetted first run with the soluble scintillator materials for a time sufficient to create a kerf having cut surfaces with solvent thereon, with the kerf cut surfaces dissolved to reshape the kerf corners, and without the formation of surface hydrates. The wetting step is accompanied by providing a second run of the wetted filament in a reverse direction and engaging the scintillator materials. The first run and second run engaging steps are concurrent with tensioning the moving filament, producing kerfs through the scintillator materials, with organic solvent delivered onto kerf surfaces.
    Type: Grant
    Filed: November 11, 1999
    Date of Patent: December 11, 2001
    Assignee: CTI, Inc.
    Inventors: Dennis E. Persyk, Mark S. Andreaco
  • Patent number: 6217341
    Abstract: An integrated circuit test socket is provided with contact holders which support torsion spring contacts in the socket. Each contact includes a length of wire which includes a wound portion with a pair of arms extending from opposite ends of the wound portion. One of the arms terminates in a portion engaging a corresponding terminal on an integrated circuit undergoing test, and the other arm includes a portion extending through a corresponding aperture in the socket to make electrical contact with a conductor of a circuit board.
    Type: Grant
    Filed: April 1, 1999
    Date of Patent: April 17, 2001
    Assignee: Wells-CTI, Inc.
    Inventors: Michael Glick, Valts Treibergs
  • Patent number: 6162066
    Abstract: A socket for positioning and installing an integrated circuit chip having terminals on one side thereof on a conductive elastomer includes a base which positions the chip over the elastomer. A camming member is moveable relative to the base between an open position disengaged from the chip and allowing the chip to be installed in the socket to a closed position in which the actuating member engages a side of the chip and exerts a force on the chip to embed the terminals in the elastomer to thereby provide an electrical connection between the terminals and the elastomer.
    Type: Grant
    Filed: May 16, 1997
    Date of Patent: December 19, 2000
    Assignee: Wells-CTI, Inc.
    Inventors: Michael Glick, Kenneth J. Mroczkiewicz
  • Patent number: 6045370
    Abstract: A socket for establishing a releasable connection between terminals of electronic modules and a circuit board includes a base having a module support surface for supporting the module in test position. A contact holder cooperates with the base for supporting contact elements for each terminal of the module. Each of the contact modules include a projecting portion projecting from the socket and before engagement with the circuit board, a support section which is supported on the contact holder in grooves defined between ribs and oriented with respect thereto by tabs on the contact elements engaging gaps in the grooves, and a deflecting section which extends over slots in the contact holder. When a module to be tested, the module is placed on the test surface and a lid pivotally mounted on the socket is closed to thereby push the terminals into engagement with the contact elements and thereafter downward force being accommodated by deflection of the deflectable portion of the contact elements into the grooves.
    Type: Grant
    Filed: October 2, 1997
    Date of Patent: April 4, 2000
    Assignee: Wells-CTi, Inc.
    Inventors: Valts Edgars Treibergs, Craig Joseph Reske
  • Patent number: 5586153
    Abstract: A process for producing radionuclides using a porous carbon target. The process includes the steps of inserting a porous carbon target with tailored solid and void dimensions in the path of a bombarding beam; introducing fluid into the porous carbon target; bombarding the porous carbon target to produce at least one type of radionuclide; collecting the fluid and separating the resulting radionuclides.
    Type: Grant
    Filed: August 14, 1995
    Date of Patent: December 17, 1996
    Assignee: CTI, Inc.
    Inventor: C. William Alvord
  • Patent number: 5296708
    Abstract: A method and apparatus for producing radioactive transmission measurements to form a 3-D image with a point source of radiation, such as required in tomography applications. This involves the passing of the point source proximate the face of each detector of the tomograph units. As such, attenuation data, transmission data, detector performance data, etc., can be obtained. This point source of radiation is rapidly circulated through a conduit that passes across each detector face under the influence of a transport fluid in, for example, an oscillatory motion to achieve a selected radiation field whereby calculation of transmission measurements within a body positioned within the tomograph scanner is achieved. When not being circulated, the radiation source is held within a shield. Circulation of the transport fluid, typically a hydraulic fluid, is typically accomplished using a positive displacement pump.
    Type: Grant
    Filed: March 26, 1993
    Date of Patent: March 22, 1994
    Assignee: CTI, Inc.
    Inventors: J. Clifton Moyers, Ronald Nutt
  • Patent number: 5224037
    Abstract: A 3-dimensional projection system (10) for the rapid back projection of multi-ring Positron Emission Tomography (PET) scan data composed of planes (44) of two-dimensional data defining individual Lines Of Response (LOR) (42) into a plurality of image voxels for three-dimensional display on a video screen. The projection system (10) of the preferred embodiment is a Very Large Scale Integration (VLSI) based architecture which will support forward and back projection for a 3-dimensional image detected by a multi-ring PET scanner. A selected number of processing engines (20) are included for forward projection and back projection, the number of engines (20) being inversely proportional to the projection time.
    Type: Grant
    Filed: March 15, 1991
    Date of Patent: June 29, 1993
    Assignee: CTI, Inc.
    Inventors: William F. Jones, Michael E. Casey, Larry G. Byars