Abstract: A method for fabricating an array adapted to receive a plurality of scintillators for use in association with an imaging device. The method allows the creation of a detector array such that location of the impingement of radiation upon an individual scintillator detector is accurately determinable. The array incorporates an air gap between all the scintillator elements. Certain scintillators may have varying height reflective light partitions to control the amount of light sharing which occurs between elements. Light transmission is additionally optimized by varying the optical transmission properties of the reflective light partition, such as by varying the thickness and optical density of the light partitions. In certain locations, no light partitions exist, thereby defining an air gap between those elements. The air gap allows a large increase in the packing fraction and therefore the overall sensitivity of the array.

Abstract: A Positron Emission Tomography (PET) tomograph having continuously rotating panel detectors. The PET tomograph includes two or more panel detector heads removably mounted on a rotating carriage system with a coincidence point source transmission system. Each panel detector head includes an array of scintillators, a light guide disposed behind the scintillators, and an array of detectors disposed behind the light guide. Each panel detector head further includes dedicated detector electronics for processing data collected from the detectors in that panel. Each detector block is comprised of an array of Lutetium Oxyorthosilicate (LSO) crystals. A rotational drive system is provided for continuously rotating the panel detector heads about the gantry frame. A data commutator is provided for communicating data from each detector panel head to a data processor. In order to remove heat generated by the panel detector heads, a chilled water cooling system is employed.

Abstract: A normalization apparatus and method for a PET scanner with panel detectors for obtaining an estimate of a normalization array, for correction for count rate effects on the normalization array, and for measurement of the relation between the normalization array and the count rate. The method of the present invention is based on two quasi-independent radial and axial components, which are count rate dependent due to sensitivity changes across the detector blocks. A scatter source is disposed at the center of the FOV and a scatter-free source is disposed at the outer edge of the FOV. The method computes the normalization array through several steps which evaluate the geometric profile, the axial profile, and the correction factor. A count rate correction is introduced to extend the normalization array to any count rate.

Abstract: A rail system for supporting a patient gantry including a fixed rail assembly mounted on a support surface and a service rail assembly releasably securable to the fixed rail assembly. Each rail assembly includes a bar and a top rail. An alignment device is provided for aligning the top rails of each assembly and is configured so that the rails cannot be interchanged. A lever is provided for positively securing the service rail assembly to either the fixed rail assembly or in a first receptor defined by a mounting block secured to a bearing block and on which is mounted the patient gantry. A toggle clamp includes a pin selectively received in a locating hole defined in the fixed rail assembly. If the toggle clamp has not been engaged and the lever does not engage the first receptor, the lever is received by a second receptor to prevent derailment.

Abstract: A method and apparatus for determining and correcting the baseline of a continuously sampled signal for use in positron emission tomography. The method employs continuous signal sampling to determine the signal level at time t(0) so that an accurate determination of an integrated signal may be calculated, resulting in an accurate energy estimate for an ac-coupled, continuously-sampled signal at various count rates. The device includes a front-end electronics processing channel including primarily an analog CMOS ASIC, a bank of ADCs, an FPGA-based digital sequencer, and two RAMs. The processing electronics perform continuous digital integration of PMT signals to obtain normalized position and energy. Continuous baseline restoration (BLR) is used, wherein the baseline of the signal pulses are placed at mid-scale by continuously sampling the ADC, thus always making available the past history. A correction signal is generated for use in negative feedback control of the baseline.

Abstract: A scintillation detector which includes a plurality of discrete scintillators composed of one or more scintillator materials. The discrete scintillators interact with incident radiation to produce a quantifiable number of photons with characteristic emission wavelength and decay time. A light guide is operatively associated with the scintillation crystals and may be either active or non-active and segmented or non-segmented depending upon the embodiment of the design. Photodetectors are provided to sense and quantify the scintillation light emissions. The process and system embodying various features of the present invention can be utilized in various applications such as SPECT, PET imaging and simultaneous PET systems.

Abstract: Apparatus and methods for simulating a sheet source with a line source for determining normalization coefficients for the detectors in positron emission tomography (PET) scanners and single photon emission computed tomography (SPECT) scanners. A line source, oriented perpendicular to the axis of a scanner gantry, is moved along the axis while the detectors are stationary and positioned substantially parallel to the plane in which the source moves. In another embodiment, an axially mounted line source moves parallel to a diameter of the gantry while the stationary detectors are positioned substantially parallel to the plane in which the source moves. In still another embodiment, the line source is stationary and positioned parallel to the gantry axis and off center while the detectors move relative to the line source. A shaped attenuator is placed around the source in this last embodiment.

Abstract: A grid array adapted to receive a plurality of scintillators for use in association with an imaging device. The grid array is highly reflective such that location of the impingement of radiation upon an individual scintillator detector is accurately determinable. The grid array allows an air gap between each scintillator and the reflector material, as well as provides a highly reflective medium that produces sufficient light output while controlling cross-talk between the discrete scintillator elements. The grid array defines an M×N array of scintillator element cells. The grid array is manufactured using a conventional method such as injection molding. The grid array is fabricated from a highly reflective material. The scintillator elements are each cut to size and then inserted such that a uniform, flat surface to be achieved. In one embodiment, a bottom wall is be defined by each of the scintillator element cells.

Abstract: A patient handling system (10) for use with a medical imaging or radiation therapy device, and an associated pallet mounting apparatus (12) for releasably mounting a pallet (18) on the pallet support assembly (16) of a patient handling system. The patient handling system (10) includes a pallet (18) for supporting a patient, and a pallet support assembly (16) for supporting the pallet (18) and for positioning the pallet (18) to facilitate the scanning of a patient positioned on the pallet (18) using the medical imaging device, or to facilitate the application of radiation therapy to a patient using a radiation therapy device.

Abstract: A method for producing a high resolution detector array so as to provide very high packing fraction, i.e. the distance between scintillator elements is minimized so the detector efficiency will be higher than is currently achievable. In the preferred embodiment of the present invention, the fabrication methodology is enhanced by handling LSO bars rather than single crystals when gluing on the Lumirror® as well as etching the LSO. Namely, an LSO boule is cut into wide bars of a selected dimension, for example 30 mm, which are then acid etched or mechanically polished. A selected number, N, of these LSO bars can then be glued together with Lumirror® sheets between each bar (coating the LSO disks and Lumirror® sheets with Epotek 301-2). The glued bar block is then cut again into bars in a perpendicular direction, and these new LSO-Lumirror® bars are etched.

Abstract: A coincidence transmission source serves to detect coincident activity from a radiation source. The coincidence transmission source includes a detector dedicated to collecting attenuation data. A collimated radiation source and a detector are positioned with respect to a tomography device such that only a selected strip of the imaging detector of the tomograph is illuminated such that events unrelated to the attenuation are eliminated. The coincidence transmission source includes a collimator in which is disposed a radiation source. Fiber optics are interconnected between a plurality of dedicated gamma radiation detectors and a plurality of photomultiplier tubes. The arrangement of fiber optics is designed such that the address of a particular gamma radiation detector is readily discernable while minimizing the number of PMT's required to process data accumulated by the gamma radiation detectors.

Abstract: An apparatus for providing source information to a positron emission tomography (PET) scanner upon demand, and a method for using same. An intelligent coincidence transmission source with multiple point sources includes data in a storage device. The data includes the date of manufacture, the activity level at that date, and other information. The data is provided to the scanner's computer system upon demand. The apparatus includes flexible means for maintaining electrical communication between the data storage device and the scanner.

Abstract: A combined PET and X-Ray CT tomograph for acquiring CT and PET images sequentially in a single device, overcoming alignment problems due to internal organ movement, variations in scanner bed profile, and positioning of the patient for the scan. In order to achieve good signal-to-noise (SNR) for imaging any region of the body, an improvement to both the CT-based attenuation correction procedure and the uniformity of the noise structure in the PET emission scan is provided. The PET/CT scanner includes an X-ray CT and two arrays of PET detectors mounted on a single support within the same gantry, and rotate the support to acquire a full projection data set for both imaging modalities. The tomograph acquires functional and anatomical images which are accurately co-registered, without the use of external markers or internal landmarks.

Abstract: An apparatus and method for determining the total energy of a continuously under-sampled energy signal resulting from an annihilation event detected by a positron emission tomograph (PET) scanner. An annihilation event is detected by a scintillator crystal and photomultiplier tube, which produces an energy signal that is continuously under-sampled by an analog-to-digital converter. The start time of the energy signal is determined by a constant fraction discriminator and time-to-digital converter. The start time is used to calculate a new amplitude for each sample, from which the total energy can be calculated.

Abstract: An apparatus and method for determining the total energy of a continuously under-sampled energy signal resulting from an annihilation event detected by a positron emission tomograph (PET) scanner. An annihilation event is detected by a scintillator crystal and photomultiplier tube, which produces an energy signal that is continuously under-sampled by an analog-to-digital converter. The start time of the energy signal is determined by a constant fraction discriminator and time-to-digital converter. The start time is used to calculate a new amplitude for each sample, from which the total energy can be calculated.

Abstract: A method for performing accurate iterative reconstruction of image data sets based on Approximate Discrete Radon Transformation (ADRT). ADRT and its inverse are implemented to provide exactly matched forward and backward projectors suitable for the Maximum-Likelihood Expectation-Maximization (ML-EM) reconstruction in PET. A 2D EM reconstruction algorithm is accomplished by initializing an estimation image. A back projection of the projection weights is then formed. A loop is begun with a controlled number of iterations. The estimated image is then forward projected using linogram coordinates. A correction ratio linogram is formed and correction factors are back projected. A normalization factor is then applied. This 2D EM method is extendable into 3D reconstructions using 3D PET lines of response. Forward projection is performed on planes extracted from the image voxels. Back projection is also performed in 2D planes, which are subsequently added into the 3D array with the correct orientations.

Abstract: A combined PET and X-Ray CT tomograph for acquiring CT and PET images sequentially in a single device, overcoming alignment problems due to internal organ movement, variations in scanner bed profile, and positioning of the patient for the scan. In order to achieve good signal-to-noise (SNR) for imaging any region of the body, an improvement to both the CT-based attenuation correction procedure and the uniformity of the noise structure in the PET emission scan is provided. The PET/CT scanner includes an X-ray CT and two arrays of PET detectors mounted on a single support within the same gantry, and rotate the support to acquire a full projection data set for both imaging modalities. The tomograph acquires functional and anatomical images which are accurately co-registered, without the use of external markers or internal landmarks.

Abstract: Apparatus and methods for simulating a sheet source with a line source for determining normalization coefficients for the detectors in positron emission tomography (PET) scanners and single photon emission computed tomography (SPECT) scanners. A line source, oriented perpendicular to the axis of a scanner gantry, is moved along the axis while the detectors are stationary and positioned substantially parallel to the plane in which the source moves. In another embodiment, an axially mounted line source moves parallel to a diameter of the gantry while the stationary detectors are positioned substantially parallel to the plane in which the source moves. In still another embodiment, the line source is stationary and positioned parallel to the gantry axis and off center while the detectors move relative to the line source. A shaped attenuator is placed around the source in this last embodiment.

Abstract: Apparatus and methods for three dimensional image reconstruction from data acquired in a positron emission tomograph (PET). This invention uses a parallel/pipelined architecture for processing the acquired data as it is acquired from the scanner. The asynchronously acquired data is synchronously stepped through the stages performing histogramming, normalization, transmission/attenuation, Mu image reconstruction, attenuation correction, rebinning, image reconstruction, scatter correction, and image display.

Abstract: A coincidence transmission source serves to detect coincident activity from a radiation source. The coincidence transmission source includes a detector dedicated to collecting attenuation data. A collimated radiation source and a detector are positioned with respect to a tomography device such that only a selected strip of the imaging detector of the tomograph is illuminated such that events unrelated to the attenuation are eliminated. The coincidence transmission source includes a collimator in which is disposed a radiation source. An opening is defined by the collimator for exposing a selected portion of the imaging detectors of the tomograph device. Positioned behind the radiation source, relative to the imaging detectors, is the dedicated attenuation detector. The attenuation detector and collimator are designed to illuminate only a strip of the imaging detector, thereby eliminating events not of interest in the attenuation measurement.