Abstract: The cephalosporin compound of formula (I) is disclosed, which exhibits antibiotic activity against Gram-negative (e.g., Pseudomonas aeruginosa) and Gram-positive (e.g., methicillin-resistant Staphylococcus aureus) bacteria. Methods of manufacturing the compound of formula (I), and uses of the compound in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.
Type:
Grant
Filed:
September 6, 2013
Date of Patent:
August 19, 2014
Assignee:
Cubist Pharmacueticals, Inc.
Inventors:
Yong He, Yu Gui Gu, Ning Yin, Dong Zou, Andre Lee Pearson