Abstract: An improved pipette sampling system for removing and transferring a plurality of liquid samples to and from a multi-well tray is disclosed. A pipette sampling system comprises a housing having elongated plates defining a first chamber therein. A patterned array of collector conduits is joined to the plates such that a first outwardly extending section extends into the chamber and a second outwardly extending section extends away from the chamber and towards the tray. A patterned array of tubular pipette tips are removably joined to and in flow communication with said array of collector conduits. The tips and conduits are designed to contain small, measured volumes of fluid.