Patents Assigned to Cumberland Pharmaceuticals Inc.
  • Publication number: 20240024411
    Abstract: Methods for preventing or treating a Bacillus anthracis (anthrax) infection in a subject, such as a mammal, by administering to the subject telavancin or a pharmaceutically-acceptable salt thereof.
    Type: Application
    Filed: November 22, 2022
    Publication date: January 25, 2024
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo PAVLIV, Ines MACIAS-PEREZ
  • Patent number: 11806400
    Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.
    Type: Grant
    Filed: May 7, 2020
    Date of Patent: November 7, 2023
    Assignee: Cumberland Pharmaceuticals Inc.
    Inventors: Leo Pavliv, Andrew Vila
  • Patent number: 11571412
    Abstract: The present invention is directed to methods of treating AERD (aspirin exacerbated respiratory disease) and/or asthma via the administration of a thromboxane receptor antagonist to a patient in need thereof.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: February 7, 2023
    Assignee: Cumberland Pharmaceuticals Inc.
    Inventor: Leo Pavliv
  • Publication number: 20220233473
    Abstract: A ready-to-administer stable injectable norepinephrine solution comprising water, norepinephrine, and a tonicity agent. The solution has a pH from 3.7 to 4.3 and is substantially free of chelating agents and antioxidants.
    Type: Application
    Filed: January 26, 2022
    Publication date: July 28, 2022
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo PAVLIV, Andrew VILA
  • Publication number: 20220218672
    Abstract: The present invention is directed to methods of treating AERD (aspirin exacerbated respiratory disease) and/or asthma via the administration of a thromboxane receptor antagonist to a patient in need thereof.
    Type: Application
    Filed: March 28, 2022
    Publication date: July 14, 2022
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventor: Leo PAVLIV
  • Publication number: 20220211674
    Abstract: The present invention is directed to methods of treating AERD (aspirin exacerbated respiratory disease) and/or asthma via the administration of a thromboxane receptor antagonist to a patient in need thereof.
    Type: Application
    Filed: March 28, 2022
    Publication date: July 7, 2022
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventor: Leo PAVLIV
  • Publication number: 20210106561
    Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.
    Type: Application
    Filed: October 23, 2020
    Publication date: April 15, 2021
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo Pavliv, Andrew Vila
  • Patent number: 10925860
    Abstract: The present invention is directed to methods of treating, preventing, and/or ameliorating fibrosis syndrome, and in particular cardiac fibrosis, by administration of a therapeutically effective amount of ifetroban, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: January 27, 2020
    Date of Patent: February 23, 2021
    Assignees: Cumberland Pharmaceuticals, Inc., Vanderbilt University
    Inventors: Leo Pavliv, Bryan Voss, James West, Erica Carrier
  • Publication number: 20200375953
    Abstract: The present invention is directed to methods of treating hepatorenal syndrome by administration of a therapeutically effective amount of a thromboxane A2 receptor antagonist to a patient in need thereof. The present invention is also directed to methods of treating hepatic encephalopathy and cerebral edema by administration of a therapeutically effective amount of a thromboxane A2 receptor antagonist to a patient in need thereof.
    Type: Application
    Filed: June 16, 2020
    Publication date: December 3, 2020
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo PAVLIV, Martin OGLETREE
  • Publication number: 20200316022
    Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.
    Type: Application
    Filed: June 29, 2020
    Publication date: October 8, 2020
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo PAVLIV, Andrew Vila
  • Patent number: 10751383
    Abstract: Doses and methods for administering telavancin or a pharmaceutically-acceptable salt thereof to a human patient having an infection caused by Staphylococcus aureus, such as bacteremia, pneumonia, endocarditis, osteomyelitis, a prosthetic joint infection or a complicated skin and skin structure infection, are disclosed. Also disclosed are methods for treating an infection caused by Staphylococcus aureus in a human patient using telavancin or a pharmaceutically-acceptable salt thereof. The dose of telavancin administered to the patient is determined, in part, by the weight and creatinine clearance of the patient.
    Type: Grant
    Filed: April 4, 2018
    Date of Patent: August 25, 2020
    Assignee: CUMBERLAND PHARMACEUTICALS INC.
    Inventors: Steven L. Barriere, Arthur Lo, Mathai Mammen, Philip Worboys
  • Publication number: 20200171007
    Abstract: The present invention is directed to methods of treating hepatorenal syndrome by administration of a therapeutically effective amount of a thromboxane A2 receptor antagonist to a patient in need thereof. The present invention is also directed to methods of treating hepatic encephalopathy and cerebral edema by administration of a therapeutically effective amount of a thromboxane A2 receptor antagonist to a patient in need thereof.
    Type: Application
    Filed: February 4, 2020
    Publication date: June 4, 2020
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo PAVLIV, Martin OGLETREE
  • Publication number: 20200121793
    Abstract: A pharmaceutical composition and method for providing a reduction in side effects for human patients in need of therapy comprising the administration of a pharmaceutical composition comprising acetylcysteine is disclosed.
    Type: Application
    Filed: December 18, 2019
    Publication date: April 23, 2020
    Applicant: Cumberland Pharmaceuticals, Inc.
    Inventors: Leo Pavliv, Amy Rock
  • Patent number: 10583126
    Abstract: The present invention is directed to methods of treating, preventing, and/or ameliorating fibrosis syndrome, and in particular cardiac fibrosis, by administration of a therapeutically effective amount of ifetroban, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 23, 2019
    Date of Patent: March 10, 2020
    Assignees: CUMBERLAND PHARMACEUTICALS INC., Vanderbilt University
    Inventors: Leo Pavliv, Bryan Voss, James West, Erica Carrier
  • Publication number: 20190343810
    Abstract: The present invention is directed to methods of treating hepatorenal syndrome by administration of a therapeutically effective amount of a thromboxane A2 receptor antagonist to a patient in need thereof. The present invention is also directed to methods of treating hepatic encephalopathy and cerebral edema by administration of a therapeutically effective amount of a thromboxane A2 receptor antagonist to a patient in need thereof.
    Type: Application
    Filed: July 28, 2019
    Publication date: November 14, 2019
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo PAVLIV, Martin OGLETREE
  • Publication number: 20190269778
    Abstract: A pharmaceutical composition and method for providing a reduction in side effects for human patients in need of therapy comprising the administration of a pharmaceutical composition comprising acetylcysteine is disclosed.
    Type: Application
    Filed: May 14, 2019
    Publication date: September 5, 2019
    Applicant: Cumberland Pharmaceuticals, Inc.
    Inventors: Leo Pavliv, Amy Rock
  • Publication number: 20190247365
    Abstract: The present invention is directed to methods of treating hepatorenal syndrome by administration of a therapeutically effective amount of a thromboxane A2 receptor antagonist to a patient in need thereof. The present invention is also directed to methods of treating hepatic encephalopathy and cerebral edema by administration of a therapeutically effective amount of a thromboxane A2 receptor antagonist to a patient in need thereof.
    Type: Application
    Filed: April 23, 2019
    Publication date: August 15, 2019
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo PAVLIV, Martin OGLETREE
  • Patent number: 10314824
    Abstract: The present invention is directed to methods of treating, preventing, and/or ameliorating fibrosis syndrome, and in particular cardiac fibrosis, by administration of a therapeutically effective amount of ifetroban, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: June 11, 2018
    Date of Patent: June 11, 2019
    Assignees: Cumberland Pharmaceuticals Inc., Vanderbilt University
    Inventors: Leo Pavliv, Bryan Voss, James West, Erica Carrier
  • Publication number: 20190117621
    Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.
    Type: Application
    Filed: December 21, 2018
    Publication date: April 25, 2019
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo PAVLIV, Andrew Vila
  • Publication number: 20180344693
    Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.
    Type: Application
    Filed: August 13, 2018
    Publication date: December 6, 2018
    Applicant: Cumberland Pharmaceuticals Inc.
    Inventors: Leo PAVLIV, Andrew Vila