Abstract: The invention relates to a biologically degradable composite material and to a process for the preparation thereof. The biologically degradable composite material according to the invention is preferably a bone reconstruction material which can be used in the field of regenerative medicine, especially as a temporary bone defect filler for bone regeneration.
Abstract: The invention relates to a bone formation agent of porous calcium phosphate having an isotropic sintered structure and, between the particles of the calcium phosphate, statistically distributed pores in a plurality of discrete size ranges. The bone formation agent has at least two, preferably three, discrete pore size distributions. Its porosity has an irregular geometric shape. The sintered particles of the calcium phosphate have a particle size smaller than 63 ?m with a d50 value in the range from 5 to 20 ?m. The interconnecting pore share in the overall porosity is limited to pore sizes less than 10 ?m. The bone formation agent can be used in the form of a granulate or shaped body for bone regeneration. In the case of granulates, the maximum pore diameters are matched to the granulate diameter. The invention relates also to a method of producing the bone formation agent.
Type:
Grant
Filed:
June 25, 2004
Date of Patent:
July 15, 2014
Assignee:
Curasan AG
Inventors:
Fabian Peters, Frank Palm, Joachim Wittner, Ute Reif
Abstract: The invention relates to a biologically degradable composite material and to a process for the preparation thereof. The biologically degradable composite material according to the invention is preferably a bone reconstruction material which can be used in the field of regenerative medicine, especially as a temporary bone defect filler for bone regeneration.
Abstract: A method of producing a self-hardening, bioabsorbable composite material, the material produced and its areas of application are described. The method is based on the principal method steps (I) immobilisation of a polymerisation initiator in a microporous pore system of a first partial amount of a bioabsorbable calcium phosphate used in producing the self-hardening, bioabsorbable composite material, (II) immobilisation of a polymerisation activator in the microporous pore system of a second partial amount of the bioabsorbable calcium phosphate used in producing the self-hardening, bioabsorbable composite material and (III) homogeneous mixing of the components according to (I) and (II) with a liquid or paste-form, multi-functional monomer capable of forming a biocompatible, bioabsorbable polymer network or a corresponding monomer mixture and, optionally, with further constituents which modify the properties of the monomer or monomer mixture.
Type:
Grant
Filed:
November 25, 2004
Date of Patent:
February 4, 2014
Assignee:
Curasan AG
Inventors:
Matthias Schnabelrauch, Sebastian Vogt, Ute (Erbe) Reif
Abstract: The invention relates to a phase and sedimentation-stable, plastically deformable preparation with intrinsic pore formation that can be used for instance for filling bone defects and for augmentation, and also relates to a method for producing same.
Abstract: The invention relates to a resorbable bone replacement and bone formation material (augmentation material) based on porous ?-tricalcium phosphate (?-TCP).
Type:
Grant
Filed:
February 26, 2002
Date of Patent:
August 8, 2006
Assignee:
curasan AG
Inventors:
Helmut Heide, Joachim Pabst, Albrecht Dinkelaker, Olaf Pobantz
Abstract: The invention relates to a resorbable bone replacement and bone formation material (augmentation material) based on porous ?-tricalcium phosphate (?-TCP).
Type:
Grant
Filed:
August 31, 2004
Date of Patent:
March 14, 2006
Assignee:
curasan AG
Inventors:
Helmut Heide, Joachim Pabst, Albrecht Dinkelaker, Olaf Pobantz