Patents Assigned to CURATE BIOSCIENCES LLC
  • Methods and devices for micro-isolation, extraction, and/or analysis of microscale components in an array
    Patent number: 10457937
    Abstract: Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation device described can comprise a photomask that protects regions of interest against DNA-destroying illumination. The micro-isolation device can further comprise photosensitive material defining access wells following illumination and subsequent developing of the photosensitive material. The micro-isolation device can further comprise a chambered microfluidic device comprising channels providing access to wells defined in photosensitive material. The micro-isolation device can comprise a chambered microfluidic device without access wells defined in photosensitive material where valves control the flow of gases or liquids through the channels of the microfluidic device.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: October 29, 2019
    Assignees: CALIFORNIA INSTITUTE OF TECHNOLOGY, UNIVERSITY OF SOUTHERN CALIFORNIA, CURATE BIOSCIENCES LLC
    Inventors: Emil P. Kartalov, Cheng-Chung Lee, Paul Predki
  • Methods and devices for micro-isolation, extraction, and/or analysis of microscale components in an array
    Patent number: 10174313
    Abstract: Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation device described can comprise a photomask that protects regions of interest against DNA-destroying illumination. The micro-isolation device can further comprise photosensitive material defining access wells following illumination and subsequent developing of the photosensitive material. The micro-isolation device can further comprise a chambered microfluidic device comprising channels providing access to wells defined in photosensitive material. The micro-isolation device can comprise a chambered microfluidic device without access wells defined in photosensitive material where valves control the flow of gases or liquids through the channels of the microfluidic device.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: January 8, 2019
    Assignees: CALIFORNIA INSTITUTE OF TECHNOLOGY, UNIVERSITY OF SOUTHERN CALIFORNIA, CURATE BIOSCIENCES LLC
    Inventors: Emil P. Kartalov, Cheng-Chung Lee, Paul Predki
  • Methods and devices for micro-isolation, extraction, and/or analysis of microscale components in an array
    Patent number: 9920315
    Abstract: Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation device described can comprise a photomask that protects regions of interest against DNA-destroying illumination. The micro-isolation device can further comprise photosensitive material defining access wells following illumination and subsequent developing of the photosensitive material. The micro-isolation device can further comprise a chambered microfluidic device comprising channels providing access to wells defined in photosensitive material. The micro-isolation device can comprise a chambered microfluidic device without access wells defined in photosensitive material where valves control the flow of gases or liquids through the channels of the microfluidic device.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: March 20, 2018
    Assignees: CALIFORNIA INSTITUTE OF TECHNOLOGY, UNIVERSITY OF SOUTHERN CALIFORNIA, CURATE BIOSCIENCES LLC
    Inventors: Emil P. Kartalov, Cheng-Chung Lee, Paul Predki