Patents Assigned to CUTISS AG
  • Patent number: 12611203
    Abstract: The present invention relates to a device adapted to facilitate transport of a biopsy sample from a sterile extraction site to laboratory-type equipment by which the biopsy sample is processed, while maintaining the biopsy sample wetted and sterile and automatically transferring the biopsy sample from the device to the laboratory-type equipment.
    Type: Grant
    Filed: June 3, 2020
    Date of Patent: April 28, 2026
    Assignee: CUTISS AG
    Inventors: Astrid Welti, Claude Holenstein, Vincent Ronfard, Anna-Lena Dittrich, Reto Frei, Christian Wullschleger, Sebastian Wollmann
  • Patent number: 12599401
    Abstract: Various methods for producing skin grafts for rehabilitation of skin defects are carried out in a closed system operated and controlled in an automated manner. A skin biopsy may be separated into a dermis layer and an epidermis layer prior to formation of a skin graft. A total skin graft area produced may be 9 times to 1000 times greater than a total skin biopsy area that provides cells for the graft. Differences in density between dermis and epidermis may aid in separation between a dermis layer and an epidermis layer.
    Type: Grant
    Filed: November 22, 2020
    Date of Patent: April 14, 2026
    Assignee: Cutiss AG
    Inventors: Vincent Ronfard, Claude Holenstein, Anna-Lena Dittrich, Laurent Barnes, Reto Frei, Ulrich Öffinger, Boris Stolz
  • Patent number: 12564662
    Abstract: The invention relates to a fully disposable system for casting, polymerizing and compressing a hydrogel. The invention further relates to a method for producing a scaffold for the generation of artificial tissue products using said disposable system.
    Type: Grant
    Filed: March 1, 2021
    Date of Patent: March 3, 2026
    Assignee: Cutiss AG
    Inventors: Claude Nicolas Holenstein, Jerry Donnan, Vincent Ronfard
  • Patent number: 12516281
    Abstract: The present invention relates to a device and method for automatically isolating viable cells from connective, epithelial or other tissue, and, if the tissue is multilayered, for automatically separating one tissue layer from another.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: January 6, 2026
    Assignee: CUTISS AG
    Inventors: Claude Nicolas Holenstein, Vincent Ronfard, Anna-Lena Dittrich, Reto Frei, Christian Stefan Wullschleger, Jascha Eisenberg, Sebastian Wollmann
  • Patent number: 12465670
    Abstract: The invention relates to a fully disposable system for casting, polymerizing and compressing a hydrogel. The invention further relates to a method for producing a scaffold for the generation of artificial tissue products using said disposable system.
    Type: Grant
    Filed: January 17, 2025
    Date of Patent: November 11, 2025
    Assignee: Cutiss AG
    Inventors: Claude Nicolas Holenstein, Jerry Donnan, Vincent Ronfard
  • Patent number: 12286611
    Abstract: A tissue culture vessel including a graft support tray (200) and a box having a lid (400) and a base which engages and retains the tray. The tray has two operational states: a first operational state in which a floor of the tray is slightly raised with respect to a floor of the base and a second operational state in which the floor of said tray descends to contact the floor of the base.
    Type: Grant
    Filed: June 20, 2022
    Date of Patent: April 29, 2025
    Assignee: Cutiss AG
    Inventors: Claude Nicolas Holenstein, Vincent Ronfard, Anna-Lena Dittrich, Siegfried Graf, Christian Beyer, Krzysztof Krasnopolski, Diane Ledroit, Gilles Weder, Roman Arnet, Noa Schmid, Charles Coen
  • Publication number: 20240026291
    Abstract: The invention relates to a device (1) for preparing a cell suspension comprising an enzyme reservoir (10), a first purification compartment (20) for receiving a first purification material (P1), wherein the first purification compartment (20) is in fluid connection or can be brought into fluid connection with the enzyme reservoir (10), a syringe (40) comprising a barrel (41) defining a barrel compartment (45) and a piston (42) which is movably arranged in the barrel compartment (45), wherein the syringe (40) comprises a syringe inlet (43) connected to the barrel compartment (45), wherein the syringe inlet (43) is in fluid connection or can be brought into fluid connection with the first purification compartment (20), and wherein the syringe (40) comprises a syringe outlet (44), and wherein the device (1) comprises a flow path from the enzyme reservoir (10) via the first purification compartment (20) to the syringe inlet (43). Also provided herein are methods for preparing a cell suspension.
    Type: Application
    Filed: December 1, 2021
    Publication date: January 25, 2024
    Applicant: CUTISS AG
    Inventors: Vincent RONFARD, Joaquin URDINEZ, Claude HOLENSTEIN