Abstract: An automatic valve shut-off system useful for gas cylinders and the like employing a pneumatically actuated rotatable shaft to engage the valve handle on the cylinder. A control box is located remotely and conduits carry pressurized gas to energize the pneumatic activator. Solenoid or manual type operated switches select the delivery of pressurized gas to the cylinder and a pneumatic feed back device is provided to indicate the position of the valve handle.