Patents Assigned to Cyberheart, Inc.
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Patent number: 10792511Abstract: The invention provides a non-invasive method for treatment of arrhythmia. In a first aspect, a method for treatment of atrial fibrillation in a heart of a patient comprises directing radiation from outside the patient toward one or more target treatment regions of the heart so as to inhibit the atrial fibrillation. The radiation may induce isolation of a pulmonary vein.Type: GrantFiled: January 26, 2018Date of Patent: October 6, 2020Assignee: Cyberheart, Inc.Inventors: Michail Pankratov, Federico Benetti, Judie Vivian
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Publication number: 20190351254Abstract: A system that generates a three-dimensional model of a tissue surface, for example the inner surface of the heart from two-dimensional image data slices. On this surface, one or more pattern lines are drawn, e.g., by a physician using a user interface, to designate desired lesion(s) on the surface. From the pattern lines, a three-dimensional volume for a lesion can be determined using known constraints. Advantageously, the series of boundaries generated by the three-dimensional volume may be projected back onto the individual CT scans, which then may be transferred to a standard radiosurgical planning tool. A dose cloud may also be projected on the model to aid in evaluating a plan.Type: ApplicationFiled: November 19, 2018Publication date: November 21, 2019Applicant: CyberHeart, Inc.Inventors: Thilaka Sumanaweera, Ed Gardner, Oliver Blanck, Tao Cai, Darrin Uecker, Patrick Maguire
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Publication number: 20190321658Abstract: Method and systems are disclosed for radiating a moving target inside a heart. The method includes acquiring sequential volumetric representations of an area of the heart and defining a target tissue region and/or a radiation sensitive structure region in 3D for a first of the representations. The target tissue region and/or radiation sensitive structure region are identified for another of the representations by an analysis of the area of the heart from the first representation and the other representation. Radiation beams to the target tissue region are fired in response to the identified target tissue region and/or radiation sensitive structure region from the other representation.Type: ApplicationFiled: November 19, 2018Publication date: October 24, 2019Applicant: CyberHeart, Inc.Inventors: Thilaka Sumanaweera, Patrick Maguire
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Patent number: 9968801Abstract: Method and systems are disclosed for radiating a moving target inside a heart. The method includes acquiring sequential volumetric representations of an area of the heart and defining a target tissue region and/or a radiation sensitive structure region in 3D for a first of the representations. The target tissue region and/or radiation sensitive structure region are identified for another of the representations by an analysis of the area of the heart from the first representation and the other representation. Radiation beams to the target tissue region are fired in response to the identified target tissue region and/or radiation sensitive structure region from the other representation.Type: GrantFiled: February 17, 2015Date of Patent: May 15, 2018Assignee: CyberHeart, Inc.Inventors: Thilaka Sumanaweera, Patrick Maguire, Edward Gardner
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Patent number: 9907978Abstract: The invention provides a non-invasive method for treatment of arrhythmia. In a first aspect, a method for treatment of atrial fibrillation in a heart of a patient comprises directing radiation from outside the patient toward one or more target treatment regions of the heart so as to inhibit the atrial fibrillation. The radiation may induce isolation of a pulmonary vein.Type: GrantFiled: February 25, 2014Date of Patent: March 6, 2018Assignee: CyberHeart, Inc.Inventors: Michail Pankratov, Federico Benetti, Judie Vivian
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Publication number: 20170065831Abstract: A system that generates a three-dimensional model of a tissue surface, for example the inner surface of the heart from two-dimensional image data slices. On this surface, one or more pattern lines are drawn, e.g., by a physician using a user interface, to designate desired lesion(s) on the surface. From the pattern lines, a three-dimensional volume for a lesion can be determined using known constraints. Advantageously, the series of boundaries generated by the three-dimensional volume may be projected back onto the individual CT scans, which then may be transferred to a standard radiosurgical planning tool. A dose cloud may also be projected on the model to aid in evaluating a plan.Type: ApplicationFiled: November 21, 2016Publication date: March 9, 2017Applicant: CyberHeart, Inc.Inventors: Thilaka Sumanaweera, Ed Gardner, Oliver Blanck, Tao Cai, Darrin Uecker, Patrick Maguire
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Patent number: 9504853Abstract: A system that generates a three-dimensional model of a tissue surface, for example the inner surface of the heart from two-dimensional image data slices. On this surface, one or more pattern lines are drawn, e.g., by a physician using a user interface, to designate desired lesion(s) on the surface. From the pattern lines, a three-dimensional volume for a lesion can be determined using known constraints. Advantageously, the series of boundaries generated by the three-dimensional volume may be projected back onto the individual CT scans, which then may be transferred to a standard radiosurgical planning tool. A dose cloud may also be projected on the model to aid in evaluating a plan.Type: GrantFiled: November 2, 2015Date of Patent: November 29, 2016Assignee: CyberHeart, Inc.Inventors: Thilaka Sumanaweera, Ed Gardner, Oliver Blanck, Tao Cai, Darrin Uecker, Patrick Maguire
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Publication number: 20160279442Abstract: The invention provides a non-invasive method for treatment of arrhythmia. In a first aspect, a method for treatment of atrial fibrillation in a heart of a patient comprises directing radiation from outside the patient toward one or more target treatment regions of the heart so as to inhibit the atrial fibrillation. The radiation may induce isolation of a pulmonary vein.Type: ApplicationFiled: June 10, 2016Publication date: September 29, 2016Applicant: CyberHeart, Inc.Inventors: Michail Pankratov, Federico Benetti, Judie Vivian
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Patent number: 9320916Abstract: Radiosurgical treatments of tissues of the heart mitigate arrhythmias and treat other tumerous and non-tumerous disease using an implanted fiducial positioned in or near the heart using cardiac catheterization techniques. The fiducials may be implanted after diagnostic and planning images of the target tissues have been acquired. Fiducial implantation may take place the day of a scheduled radiosurgical treatment. Techniques to accommodate post-planning fiducial implantation may include registration of the implanted fiducial location with the treatment plan, and active fiducials may limit collateral imaging radiation exposure while enhancing tracking accuracy.Type: GrantFiled: September 14, 2012Date of Patent: April 26, 2016Assignee: CYBERHEART, INC.Inventors: Thilaka Sumanaweera, Ed Gardner, Oliver Blanck, Tao Cai, Darrin Uecker, Patrick Maguire
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Patent number: 9205279Abstract: A system that generates a three-dimensional model of a tissue surface, for example the inner surface of the heart from two-dimensional image data slices. On this surface, one or more pattern lines are drawn, e.g., by a physician using a user interface, to designate desired lesion(s) on the surface. From the pattern lines, a three-dimensional volume for a lesion can be determined using known constraints. Advantageously, the series of boundaries generated by the three-dimensional volume may be projected back onto the individual CT scans, which then may be transferred to a standard radiosurgical planning tool. A dose cloud may also be projected on the model to aid in evaluating a plan.Type: GrantFiled: July 16, 2010Date of Patent: December 8, 2015Assignee: CYBERHEART, INC.Inventors: Thilaka Sumanaweera, Ed Gardner, Oliver Blanck, Tao Cai, Darrin Uecker, Patrick Maguire
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Patent number: 8805481Abstract: The invention provides a non-invasive system and method for treatment of the heart. In a first aspect, a method for treatment of an anatomical site related to arrhythmogenesis of a heart of a patient comprises creating a target shape encompassing the anatomical site, directing particle beam radiation or x-ray radiation from outside the patient toward the target shape wherein one or more doses of radiation ablates the target shape and disregarding at least one orientation of cardiac motion while creating the target shape or directing the particle beam or both.Type: GrantFiled: September 14, 2012Date of Patent: August 12, 2014Assignee: CyberHeart, Inc.Inventors: Thilaka Sumanaweera, Patrick Maguire, Roderick A. Young
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Patent number: 8792613Abstract: A target motion simulator system for use in verifying target tracking with a radiation therapy device. The system comprises a radiation detection target coupled to a first motion actuator simulating a first motion of a first tissue and a fiducial coupled to a second motion actuator simulating a second motion of a second tissue offset from the first tissue, a component of the first motion being asynchronous with the second motion. A synthetic physiological signal generator is synchronized with the component of the first motion, wherein an output signal from the generator, in combination with a sensed position of the fiducial, may be used by the radiation therapy device in tracking the target.Type: GrantFiled: November 19, 2009Date of Patent: July 29, 2014Assignee: CyberHeart, Inc.Inventors: Edward Gardner, Thilaka Sumanaweera
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Patent number: 8784290Abstract: Radiosurgical treatments of tissues of the heart mitigate arrhythmias and treat other tumerous and non-tumerous disease using an implanted fiducial positioned in or near the heart using cardiac catheterization techniques. The fiducials may be implanted after diagnostic and planning images of the target tissues have been acquired. Fiducial implantation may take place the day of a scheduled radiosurgical treatment. Techniques to accommodate post-planning fiducial implantation may include registration of the implanted fiducial location with the treatment plan, and active fiducials may limit collateral imaging radiation exposure while enhancing tracking accuracy.Type: GrantFiled: July 16, 2010Date of Patent: July 22, 2014Assignee: CyberHeart, Inc.Inventors: Thilaka Sumanaweera, Ed Gardner, Oliver Blanck, Tao Cai, Darrin Uecker, Patrick Maguire
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Patent number: 8696658Abstract: The invention provides a non-invasive method for treatment of arrhythmia. In a first aspect, a method for treatment of a trial fibrillation in a heart of a patient comprises directing radiation from outside the patient toward one or more target treatment regions of the heart so as to inhibit the a trial fibrillation. The radiation may induce isolation of a pulmonary vein.Type: GrantFiled: December 14, 2009Date of Patent: April 15, 2014Assignee: CyberHeart, Inc.Inventors: Michail Pankratov, Federico Benetti, Judie Vivian
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Publication number: 20130131426Abstract: The invention provides a non-invasive system and method for treatment of the heart. In a first aspect, a method for treatment of an anatomical site related to arrhythmogenesis of a heart of a patient comprises creating a target shape encompassing the anatomical site, directing particle beam radiation or x-ray radiation from outside the patient toward the target shape wherein one or more doses of radiation ablates the target shape and disregarding at least one orientation of cardiac motion while creating the target shape or directing the particle beam or both.Type: ApplicationFiled: September 14, 2012Publication date: May 23, 2013Applicant: CyberHeart, Inc.Inventors: Thilaka Sumanaweera, Patrick Maguire, Roderick A. Young
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Publication number: 20130131425Abstract: Radiosurgical treatments of tissues of the heart mitigate arrhythmias and treat other tumerous and non-tumerous disease using an implanted fiducial positioned in or near the heart using cardiac catheterization techniques. The fiducials may be implanted after diagnostic and planning images of the target tissues have been acquired. Fiducial implantation may take place the day of a scheduled radiosurgical treatment. Techniques to accommodate post-planning fiducial implantation may include registration of the implanted fiducial location with the treatment plan, and active fiducials may limit collateral imaging radiation exposure while enhancing tracking accuracy.Type: ApplicationFiled: September 14, 2012Publication date: May 23, 2013Applicant: CyberHeart, Inc.Inventors: Thilaka Sumanaweera, Ed Gardner, Oliver Blanck, Tao Cai, Darrin Uecker, Patrick Maguire
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Publication number: 20130102896Abstract: Method and systems are disclosed for radiating a moving target inside a heart. The method includes acquiring sequential volumetric representations of an area of the heart and defining a target tissue region and/or a radiation sensitive structure region in 3D for a first of the representations. The target tissue region and/or radiation sensitive structure region are identified for another of the representations by an analysis of the area of the heart from the first representation and the other representation. Radiation beams to the target tissue region are fired in response to the identified target tissue region and/or radiation sensitive structure region from the other representation.Type: ApplicationFiled: September 14, 2012Publication date: April 25, 2013Applicant: CyberHeart, Inc.Inventors: Thilaka Sumanaweera, Patrick Maguire, Ed Gardner
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Patent number: 8345821Abstract: Method and systems are disclosed for radiating a moving target inside a heart. The method includes acquiring sequential volumetric representations of an area of the heart and defining a target tissue region and/or a radiation sensitive structure region in 3D for a first of the representations. The target tissue region and/or radiation sensitive structure region are identified for another of the representations by an analysis of the area of the heart from the first representation and the other representation. Radiation beams to the target tissue region are fired in response to the identified target tissue region and/or radiation sensitive structure region from the other representation.Type: GrantFiled: October 8, 2010Date of Patent: January 1, 2013Assignee: CyberHeart, Inc.Inventors: Thilaka Sumanaweera, Patrick Maguire, Ed Gardner
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Publication number: 20120323233Abstract: A radiosurgical method for treating cardiorenal disease of a patient, the method including directing radiosurgery radiation from outside the patient towards one or more target treatment regions encompassing sympathetic ganglia of the patient so as to inhibit the cardiorenal disease. In an exemplary embodiment, the method further includes acquiring three dimensional planning image data encompassing the first and second renal arteries, planning an ionizing radiation treatment of first and second target regions using the three dimensional planning image data so as to mitigate the hypertension, the first and second target regions encompassing neural tissue of or proximate to the first and second renal arteries, respectively, and remodeling the target regions by directing the planned radiation from outside the body toward the target regions.Type: ApplicationFiled: May 9, 2012Publication date: December 20, 2012Applicant: CyberHeart, Inc.Inventors: Patrick Maguire, Edward Gardner
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Patent number: 8315691Abstract: The invention provides a non-invasive system and method for treatment of the heart. In a first aspect, a method for treatment of an anatomical site related to arrhythmogenesis of a heart of a patient comprises creating a target shape encompassing the anatomical site, directing particle beam radiation or x-ray radiation from outside the patient toward the target shape wherein one or more doses of radiation ablates the target shape and disregarding at least one orientation of cardiac motion while creating the target shape or directing the particle beam or both.Type: GrantFiled: September 26, 2008Date of Patent: November 20, 2012Assignee: CyberHeart, Inc.Inventors: Thilaka Sumanaweera, Patrick Maguire, Roderick A. Young