Abstract: The present invention relates to substituted pyrimidines of formula I, their preparation, pharmaceutical compositions containing them and their use as inhibitors of cyclin-dependent kinases (CDKs) and hence their use in the treatment of proliferative disorders and/or viral disorders.
Type:
Grant
Filed:
November 17, 2004
Date of Patent:
October 7, 2008
Assignee:
Cyclacel Limted
Inventors:
Shudong Wang, Christopher Meades, Gavin Wood, Janice O'Boyle, Campbell McInnes, Peter Martin Fischer