Patents Assigned to Cyclops Genome Sciences Limited
  • Clean-up beads
    Patent number: 7790373
    Abstract: The present invention provides a material for separating an analyte from an undesired constituent, which material comprises a solid phase and a coating, wherein the solid phase is capable of binding the undesired constituent, and wherein the coating covers the exposed surface of the solid phase to an extent that any binding of the solid phase to the analyte is impeded. A method for preparing the material, and uses of the material for separating an analyte from an undesired constituent are also provided.
    Type: Grant
    Filed: July 23, 2004
    Date of Patent: September 7, 2010
    Assignee: Cyclops Genome Sciences Limited
    Inventor: Andrew S. Goldsborough
  • Clean-Up Beads
    Publication number: 20080220413
    Abstract: The present invention provides a material for separating an analyte from an undesired constituent, which material comprises a solid phase and a coating, wherein the solid phase is capable of binding the undesired constituent, and wherein the coating covers the exposed surface of the solid phase to an extent that any binding of the solid phase to the analyte is impeded. A method for preparing the material, and uses of the material for separating an analyte from an undesired constituent are also provided.
    Type: Application
    Filed: July 23, 2004
    Publication date: September 11, 2008
    Applicant: Cyclops Genome Sciences Limited
    Inventor: Andrew S. Goldsborough
  • Isolation of nucleic acid
    Patent number: 7244568
    Abstract: Provided is a preparative method for isolating RNA comprising an oligo-or polynucleotide from a sample, which method comprises: (a) treating the sample with a reactant capable of covalently modifying the 2?-OH position of the ribose rings of the RNA under conditions so that a proportion of the 2?-OH positions of the ribose rings bear a substituent; and (b) preparing isolated RNA therefrom by separating material containing the substituent from the sample on the basis of a property of the substituent.
    Type: Grant
    Filed: April 8, 2004
    Date of Patent: July 17, 2007
    Assignee: Cyclops Genome Sciences Limited
    Inventor: Andrew Simon Goldsborough
  • Modified polynucleotides and uses thereof
    Publication number: 20050272679
    Abstract: Provided is a polynucleotide comprising mRNA, rRNA or viral RNA, comprising ribose rings that are covalently modified at the 2?-OH position. Further provided are methods for producing a double-stranded oligo- or polynucleotide from a template comprising an oligo- or polyribonucleotide, a proportion of the ribose rings of which are covalently modified at the 2?-OH position to bear a substituent which enables replication of the template by the nucleic acid polymerase.
    Type: Application
    Filed: February 14, 2005
    Publication date: December 8, 2005
    Applicant: Cyclops Genome Sciences Limited
    Inventor: Andrew Goldsborough