Patents Assigned to Cylene Pharmaceuticals
  • Substituted quinobenzoxazine analogs
    Patent number: 7354916
    Abstract: The present invention relates to quinobenzoxazines analogs having the general formula: and pharmaceutically acceptable salts, esters and prodrugs thereof; wherein A, U, V, W, X and Z are substituents. The present invention also relates to methods for using such compounds.
    Type: Grant
    Filed: July 30, 2004
    Date of Patent: April 8, 2008
    Assignee: Cylene Pharmaceuticals
    Inventors: Jeffrey P. Whitten, Michael Schwaebe, Adam Siddiqui-Jain, Terence Moran
  • Expanded porphyrin compositions for tumor inhibition
    Patent number: 7001588
    Abstract: Expanded porphyrin comprising substitutions for at least two NH groups by S, Se or Te are non-photoactive and are selective for binding G-quadruplexes characteristic of the c-MYC control region. Accordingly, these expanded porphyrins are useful to modulate the expression of genes controlled by the formation of c-MYC type G-quadruplexes, such as c-MYC itself.
    Type: Grant
    Filed: September 12, 2003
    Date of Patent: February 21, 2006
    Assignee: Cylene Pharmaceuticals
    Inventor: Laurence H. Hurley
  • Process to prepare psorospermin
    Patent number: 6933396
    Abstract: Psorospermin and analogs thereof are made using an enantiomerically selective process
    Type: Grant
    Filed: August 28, 2003
    Date of Patent: August 23, 2005
    Assignee: Cylene Pharmaceuticals
    Inventors: Jeffrey P. Whitten, Michael Schwaebe, Terrance Moran