Abstract: Seladelpar and its salts are useful in the treatment of cholangiopathies in subjects who are intolerant of, or have an inadequate response to, obeticholic acid and/or fibrates.
Type:
Application
Filed:
January 29, 2022
Publication date:
August 4, 2022
Applicant:
CymaBay Therapeutics, Inc.
Inventors:
Yun-Jung Choi, Charles A. McWherter, Alexandra S. Steinberg, Ke Yang
Abstract: CB-0406 choline salt, especially in crystalline form and as an ansolvate, methods of preparing it, compositions containing it, and its pharmaceutical uses.
Type:
Application
Filed:
May 12, 2021
Publication date:
November 18, 2021
Applicants:
CymaBay Therapeutics, Inc., DiaTex, Inc.
Inventors:
Stephan X.M. Boerrigter, Charles A. McWherter, Robert L. Martin, Jennifer L. Nelson, Jiangao Song
Abstract: CB-0406 tromethamine salt, especially in crystalline form and as an ansolvate, methods of preparing it, compositions containing it, and its pharmaceutical uses.
Type:
Application
Filed:
May 12, 2021
Publication date:
November 18, 2021
Applicants:
CymaBay Therapeutics, Inc., DiaTex, Inc.
Inventors:
Stephan X.M. Boerrigter, Charles A. McWherter, Robert L. Martin, Jennifer L. Nelson, Jiangao Song
Abstract: Treatment of intestinal barrier dysfunction and associated diseases other than alcoholic liver disease or NAFLD/NASH with seladelpar or a salt thereof.