Patents Assigned to Cyograft Tissue Engineering, Inc.
  • Tissue engineered blood vessels and methods and apparatus for their manufacture
    Patent number: 6503273
    Abstract: The invention is a tissue engineered blood vessel (TEBV) made from a cultured fibroblast sheet rolled into a multilayer vessel which has sufficient burst strength to withstand physiological blood pressure without the inclusion of smooth muscle cells or synthetic scaffolding. The TEBV is made in a bioreactor having an enclosed chamber, a sheet growth module, a rollable mandrel and a clamp for holding the sheet to the mandrel for rolling.
    Type: Grant
    Filed: November 22, 1999
    Date of Patent: January 7, 2003
    Assignee: Cyograft Tissue Engineering, Inc.
    Inventors: Todd N. McAllister, Nicolas L'Heureux