Abstract: A method for cryo-induced renal neuromodulation includes applying cryoenergy to neural fibers that contribute to renal function, or to vascular structures that contact, feed or perfuse the neural fibers. In one embodiment, cryoenergy is applied via a distal energy-delivering section of a flexible catheter. The distal section may include a plurality of microtubes for transporting a cryogen to the distal tip. The energy-delivering section contacts and extracts heat from the wall of the renal artery. In one embodiment, the distal energy-delivering section is radially expandable. The renal nerve is cooled to a degree such that nerve function is disrupted.
Type:
Grant
Filed:
September 27, 2011
Date of Patent:
August 4, 2015
Assignee:
CyroMedix, LLC
Inventors:
Peter Littrup, Alexei Babkin, Barron Nydam, William Nydam