Patents Assigned to Cythera, Inc.
  • Definitive endoderm
    Patent number: 7704738
    Abstract: Disclosed herein are cell cultures comprising definitive endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified definitive endoderm cells as well as methods for enriching, isolating and purifying definitive endoderm cells from other cell types.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: April 27, 2010
    Assignee: Cythera, Inc.
    Inventors: Kevin Allen D'Amour, Alan D. Agulnick, Emmanuel E. Baetge
  • Methods for increasing definitive endoderm production
    Patent number: 7695963
    Abstract: Disclosed herein are methods for increasing the production of definitive endoderm cells from pluripotent stem cells. Also disclosed herein are agents capable of increasing definitive endoderm cell production.
    Type: Grant
    Filed: September 24, 2007
    Date of Patent: April 13, 2010
    Assignee: Cythera, Inc.
    Inventors: Alan Agulnick, Kevin D'Amour, Emmanuel Edward Baetge
  • Methods of producing pancreatic hormones
    Patent number: 7695965
    Abstract: Disclosed herein are methods of producing pancreatic hormone-expressing cells by first differentiating pluripotent cells in cell culture so as to produce endodermal cells, the endodermal cells being competent to further differentiate into hormone-expressing cells capable of secreting at least one pancreatic hormone in response to a physiological signal, and then, transplanting the cultured endodermal cells into an organism, such as an organism in need of an endocrine cell therapy.
    Type: Grant
    Filed: July 5, 2007
    Date of Patent: April 13, 2010
    Assignee: Cythera, Inc.
    Inventors: Laura Martinson, Evert Kroon, Kevin D'Amour, Emmanuel Edward Baetge
  • Expansion of definitive endoderm cells
    Patent number: 7625753
    Abstract: Disclosed herein are cell cultures comprising expanded definitive endoderm cells as well as methods for expanding definitive endoderm cells in culture.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: December 1, 2009
    Assignee: Cythera, Inc.
    Inventors: Olivia Kelly, Emmanuel E. Baetge, Melissa Carpenter
  • Methods for identifying factors for differentiating definitive endoderm
    Patent number: 7541185
    Abstract: Disclosed herein are methods of identifying one or more differentiation factors that are useful for differentiating cells in a cell population comprising definitive endoderm cells into cells which are capable of forming tissues and/or organs that are derived from the gut tube.
    Type: Grant
    Filed: June 23, 2005
    Date of Patent: June 2, 2009
    Assignee: Cythera, Inc.
    Inventors: Kevin Allen D'Amour, Alan D. Agulnick, Susan Eliazer, Emmanuel E. Baetge
  • Methods of producing pancreatic hormones
    Patent number: 7534608
    Abstract: Disclosed herein are methods of producing pancreatic hormone-expressing cells by first differentiating pluripotent cells in cell culture so as to produce endodermal cells, the endodermal cells being competent to further differentiate into hormone-expressing cells capable of secreting at least one pancreatic hormone in response to a physiological signal, and then, transplanting the cultured endodermal cells into an organism, such as an organism in need of an endocrine cell therapy.
    Type: Grant
    Filed: July 2, 2008
    Date of Patent: May 19, 2009
    Assignee: Cythera, Inc.
    Inventors: Laura Martinson, Evert Kroon, Kevin D'Amour, Emmanuel Edward Baetge
  • Definitive endoderm
    Patent number: 7510876
    Abstract: Disclosed herein are cell cultures comprising definitive endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified definitive endoderm cells as well as methods for enriching, isolating and purifying definitive endoderm cells from other cell types.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: March 31, 2009
    Assignee: Cythera, Inc.
    Inventors: Kevin Allen D'Amour, Alan D. Agulnick, Emmanuel E. Baetge
  • METHODS OF PRODUCING PANCREATIC HORMONES
    Publication number: 20090004152
    Abstract: Disclosed herein are methods of producing pancreatic hormone-expressing cells by first differentiating pluripotent cells in cell culture so as to produce endodermal cells, the endodermal cells being competent to further differentiate into hormone-expressing cells capable of secreting at least one pancreatic hormone in response to a physiological signal, and then, transplanting the cultured endodermal cells into an organism, such as an organism in need of an endocrine cell therapy.
    Type: Application
    Filed: July 5, 2007
    Publication date: January 1, 2009
    Applicant: CYTHERA, INC.
    Inventors: Laura Martinson, Evert Kroon, Kevin D'Amour, Emmanuel Edward Baetge