Patents Assigned to CYTOGEN, INC.
  • Androgen receptor variant-based prostate cancer patient screening method
    Patent number: 11789023
    Abstract: A method for screening a prostate cancer patient, which may analyze whether or not androgen receptor (AR)-targeted therapy is applicable to the prostate cancer patient, through optical image analysis of circulating tumor cells and an AR variant.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: October 17, 2023
    Assignee: CYTOGEN, INC.
    Inventor: Byung Hee Jeon
  • EML4-ALK gene mutation analysis method
    Patent number: 11718882
    Abstract: qRT-PCR primers capable of detecting EML4-ALK gene variant based on circulating tumor cells at a more sensitive detection limit than a conventional method. Also disclosed is a lung cancer patient screening method which is capable of detecting EML4-ALK gene variant using circulating tumor cells even in a lung cancer patient on whom ALK-FISH testing has been difficult to perform, due to difficulty in collecting a solid lung cancer tissue sample, and is able to determine whether an anticancer drug targeting the EML4-ALK gene variant may be applied to the lung cancer patient.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: August 8, 2023
    Assignee: CYTOGEN, INC.
    Inventor: Byung Hee Jeon
  • Prostate-specific membrane antigen-based prostate cancer patient screening method
    Patent number: 11513124
    Abstract: According to an embodiment of the present invention, there is provided a method of screening a prostate cancer patient by optical image analysis of a circulating tumor cell marker and a prostate-specific membrane antigen.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: November 29, 2022
    Assignee: CYTOGEN, INC.
    Inventor: Byung Hee Jeon
  • PROSTATE-SPECIFIC MEMBRANE ANTIGEN-BASED PROSTATE CANCER PATIENT SCREENING METHOD
    Publication number: 20210164983
    Abstract: According to an embodiment of the present invention, there is provided a method of screening a prostate cancer patient by optical image analysis of a circulating tumor cell marker and a prostate-specific membrane antigen.
    Type: Application
    Filed: July 17, 2018
    Publication date: June 3, 2021
    Applicant: CYTOGEN, INC.
    Inventor: Byung Hee JEON
  • ANDROGEN RECEPTOR VARIANT-BASED PROSTATE CANCER PATIENT SCREENING METHOD
    Publication number: 20200225238
    Abstract: A method for screening a prostate cancer patient, which may analyze whether or not androgen receptor (AR)-targeted therapy is applicable to the prostate cancer patient, through optical image analysis of circulating tumor cells and an AR variant.
    Type: Application
    Filed: July 17, 2018
    Publication date: July 16, 2020
    Applicant: CYTOGEN, INC.
    Inventor: Byung Hee JEON
  • AXL-BASED CANCER PATIENT SCREENING METHOD
    Publication number: 20200200757
    Abstract: According to one embodiment of the present invention, there is provided a method of screening a lung cancer patient having acquired resistance to an EGFR inhibitor by optical image analysis of circulating tumor cells and AXL.
    Type: Application
    Filed: July 17, 2018
    Publication date: June 25, 2020
    Applicant: CYTOGEN, INC.
    Inventor: Byung Hee JEON
  • EML4-ALK GENE MUTATION ANALYSIS METHOD
    Publication number: 20200140959
    Abstract: qRT-PCR primers capable of detecting EML4-ALK gene variant based on circulating tumor cells at a more sensitive detection limit than a conventional method. Also disclosed is a lung cancer patient screening method which is capable of detecting EML4-ALK gene variant using circulating tumor cells even in a lung cancer patient on whom ALK-FISH testing has been difficult to perform, due to difficulty in collecting a solid lung cancer tissue sample, and is able to determine whether an anticancer drug targeting the EML4-ALK gene variant may be applied to the lung cancer patient.
    Type: Application
    Filed: July 17, 2018
    Publication date: May 7, 2020
    Applicant: CYTOGEN, INC.
    Inventor: Byung Hee JEON