Patents Assigned to Cytometix, Inc.
  • Methods of manufacturing 14,15-epoxyeicosatrienoic acid analogs and improved therapeutic delivery of same
    Patent number: 11951083
    Abstract: Systems, compositions, and methods are disclosed for developing and delivering therapeutically effective 14,15-epoxyeicosatrienoic acid (14,15-EET) analogs, for example for pain management or treatment. Of particular interest are intermediate salts.
    Type: Grant
    Filed: July 18, 2022
    Date of Patent: April 9, 2024
    Assignee: Cytometix, Inc.
    Inventors: John R. Falck, Lane Brostrom
  • Compositions and methods for delivery of polyunsaturated fatty acid derivatives and analogs
    Patent number: 10966937
    Abstract: The present invention provides a system enabling the oral delivery of therapeutics derived from polyunsaturated fatty acids (PUFAs), their metabolites and derivatives, including, eicosanoids, prostaglandins, prostacyclins, leukotrienes, resolvins, endocannabinoids, thromboxanes, epoxyeicosa-trienoic acids (EETs), hydroxyeicostetraenoic acids (HETEs), and CMX-020. The delivery system includes a vehicle comprising a purified docosahexaenoic acid (DHA) in triglyceride or ester form; a purified eicosapentaenoic acid (EPA) in triglyceride or ester form; a combination of DHA, EPA in either triglyceride or ester forms; or a modified DHA, EPA, or omega-3 fatty acid analog; and optionally, an antioxidant, a surfactant, a solubilizer, a stabilizer, a lubricant, or a pH/tonicity adjustment agent.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: April 6, 2021
    Assignee: Cytometix, Inc.
    Inventors: Lane Brostrom, Henry Bordas-Murphy, John R. Falck
  • Arachidonic acid analogs and methods for analgesic treatment using same
    Patent number: 9096494
    Abstract: The present invention provides arachidonic acid (AA) analogs and compositions containing those analogs as active agents for use in analgesic treatments. Various methods of manufacturing the inventive compounds are provided and pharmaceutical formulations, including injectable and oral dosages, are described. Certain analogs are additionally useful as antipyretic compositions and in related fever reducing treatments.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: August 4, 2015
    Assignee: CYTOMETIX, INC.
    Inventors: Lane Brostrom, John R. Falck
  • ARACHIDONIC ACID ANALOGS AND METHODS FOR ANALGESIC TREATMENT USING SAME
    Publication number: 20140135401
    Abstract: The present invention provides arachidonic acid (AA) analogs and compositions containing those analogs as active agents for use in analgesic treatments. Various methods of manufacturing the inventive compounds are provided and pharmaceutical formulations, including injectable and oral dosages, are described. Certain analogs are additionally useful as antipyretic compositions and in related fever reducing treatments.
    Type: Application
    Filed: January 17, 2014
    Publication date: May 15, 2014
    Applicant: CYTOMETIX, INC.
    Inventors: Lane Brostrom, John R. Falck
  • Arachidonic acid analogs and methods for analgesic treatment using same
    Patent number: 8658632
    Abstract: The present invention provides arachidonic acid (AA) analogs and compositions containing those analogs as active agents for use in analgesic treatments. Various methods of manufacturing the inventive compounds are provided and pharmaceutical formulations, including injectable and oral dosages, are described. Certain analogs are additionally useful as antipyretic compositions and in related fever reducing treatments.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: February 25, 2014
    Assignee: Cytometix, Inc.
    Inventors: Lane Brostrom, John R. Falck
  • ARACHIDONIC ACID ANALOGS AND METHODS FOR ANALGESIC TREATMENT USING SAME
    Publication number: 20130023510
    Abstract: The present invention provides arachidonic acid (AA) analogs and compositions containing those analogs as active agents for use in analgesic treatments. Various methods of manufacturing the inventive compounds are provided and pharmaceutical formulations, including injectable and oral dosages, are described. Certain analogs are additionally useful as antipyretic compositions and in related fever reducing treatments.
    Type: Application
    Filed: May 25, 2012
    Publication date: January 24, 2013
    Applicant: Cytometix, Inc.
    Inventors: Lane Brostrom, John R. Falck
  • Methods and uses of leukotriene B4 hydroxylases to treat diseases
    Publication number: 20060247200
    Abstract: Methods and uses are described for treating or preventing diseases of humans or non-human animals by reducing the amount of active leukotriene B4 (LTB4) in those in need of such treatment using LTB4 hydroxylases. In certain embodiments, LTB4 hydroxylase is administered in combination with nicotinamide adenine dinucleotide phosphate and/or an NADPH-cytochrome P-450 reductase. The invention is particularly useful for treating or preventing respiratory diseases that are caused or exacerbated by inflammation.
    Type: Application
    Filed: May 1, 2006
    Publication date: November 2, 2006
    Applicants: Cytometix, Inc., The Medical College of Winsconsin Reasearch Foundation, Inc.
    Inventors: David Harder, James Antczak, Lane Brostrom