Abstract: A method for the isolation of specific molecules which bind highly selectively to chosen target molecules. In particular, due to displacement with a specific competitor, binding molecules are selected which preferably bind to previously known epitopes.
Type:
Grant
Filed:
April 29, 2005
Date of Patent:
January 12, 2016
Assignee:
CYTOTOOLS AG
Inventors:
Gerd Klock, Dirk Kaiser, Mark Andre Freyberg
Abstract: Specific amino acid sequences and peptides and/or peptide mimetics deducted therefrom influencing apoptosis, and the use thereof for the production of pharmaceuticals as diagnostic tools are shown.
Type:
Grant
Filed:
December 23, 2010
Date of Patent:
April 28, 2015
Assignee:
Cytotools AG
Inventors:
Mark A. Freyberg, Peter Friedl, Dirk Kaiser
Abstract: This invention relates to aqueous solutions of reactive chlorine compounds having the empirical formulae H2Cl2O6 or ClO3H, for example, and the derivatives, anions or salts thereof. The invention further relates to methods for the production of said compounds and the use thereof in the pharmaceutical and particularly in the medical field, in cosmetics, medicinal care and in the domains of food technology and technology.
Abstract: This invention relates to aqueous solutions of reactive chlorine compounds having the empirical formulae H2Cl2O6 or ClO3H, for example, and the derivatives, anions or salts thereof. The invention further relates to methods for the production of said compounds and the use thereof in the pharmaceutical and particularly in the medical field, in cosmetics, medicinal care and in the domains of food technology and technology.
Abstract: The invention relates to a method for identifying substances with antiapoptotic activity, where i) cells which express both CD47 and the integrin ?v?3 are cultured, ii) the cells are caused to produce an apoptosis-inducing substance, and/or a substance or substances which induces/induce apoptosis is/are added, iii) the test substance is added, and iv) the apoptosis rate is measured, and to the substances which can be identified with the method.
Type:
Application
Filed:
July 13, 2012
Publication date:
November 8, 2012
Applicant:
CYTOTOOLS AG
Inventors:
Mark A. Freyberg, Peter Friedl, Dirk Kaiser
Abstract: Specific amino acid sequences and peptides and/or peptide mimetics deducted therefrom influencing apoptosis, and the use thereof for the production of pharmaceuticals as diagnostic tools are shown.
Type:
Application
Filed:
December 23, 2010
Publication date:
July 21, 2011
Applicant:
CYTOTOOLS AG
Inventors:
Mark A. Freyberg, Peter Friedl, Dirk Kaiser
Abstract: The invention relates to anti-apoptotically active apatamers. The invention describes possible therapeutic and diagnostic applications for, among other things, treating arteriosclerosis, promoting the healing of wounds, treating AIDS, cancer, Alzheimer's disease, systemic lupus erythematosus as well a rheumatoid arthritis and other chronic inflammatory diseases.
Type:
Grant
Filed:
December 10, 2004
Date of Patent:
February 2, 2010
Assignee:
CytoTools AG
Inventors:
Gerd Klock, Mark A. Freyberg, Dirk Kaiser