Patents Assigned to CytoTools GmbH
  • Method and pharmaceutical composition for improvement of wound healing
    Patent number: 8349369
    Abstract: This invention relates to aqueous solutions of reactive chlorine compounds having the empirical formulae H2Cl2O6 or ClO3H, for example, and the derivatives, anions or salts thereof. The invention further relates to methods for the production of said compounds and the use thereof in the pharmaceutical and particularly in the medical field, in cosmetics, medicinal care and in the domains of food technology and technology.
    Type: Grant
    Filed: October 7, 2009
    Date of Patent: January 8, 2013
    Assignee: CytoTools GmbH
    Inventors: Klaus J. Wannowius, Dirk Kaiser
  • Method for treating vascular disorders
    Patent number: 8252283
    Abstract: The invention relates to a method for identifying substances with antiapoptotic activity, where i) cells which express both CD47 and the integrin ?v?3 are cultured, ii) the cells are caused to produce an apoptosis-inducing substance, and/or a substance or substances which induces/induce apoptosis is/are added, iii) the test substance is added, and iv) the apoptosis rate is measured, and to the substances which can be identified with the method.
    Type: Grant
    Filed: February 20, 2009
    Date of Patent: August 28, 2012
    Assignee: Cytotools GmbH
    Inventors: Mark A. Freyberg, Peter Friedl, Dirk Kaiser
  • Apoptotically active peptides
    Patent number: 7892556
    Abstract: Specific amino acid sequences and peptides and/or peptide mimetics deducted therefrom influencing apoptosis, and the use thereof for the production of pharmaceuticals as diagnostic tools are shown.
    Type: Grant
    Filed: December 18, 2002
    Date of Patent: February 22, 2011
    Assignee: CytoTools GmbH
    Inventors: Mark A. Freyberg, Peter Friedl, Dirk Kaiser
  • Method for the preparation of aqueous solutions of reactive chlorine compounds
    Patent number: 7618655
    Abstract: This invention relates to aqueous solutions of reactive chlorine compounds having the empirical formulae H2Cl2O6 or ClO3H, for example, and the derivatives, anions or salts thereof. The invention further relates to methods for the production of said compounds and the use thereof in the pharmaceutical and particularly in the medical field, in cosmetics, medicinal care and in the domains of food technology and technology.
    Type: Grant
    Filed: November 22, 2004
    Date of Patent: November 17, 2009
    Assignee: CytoTools GmbH
    Inventors: Klaus J. Wannowius, Dirk Kaiser
  • Method for Treating Vascular Disorders
    Publication number: 20090162381
    Abstract: The invention relates to a method for identifying substances with antiapoptotic activity, where i) cells which express both CD47 and the integrin ?v?3 are cultured, ii) the cells are caused to produce an apoptosis-inducing substance, and/or a substance or substances which induces/induce apoptosis is/are added, iii) the test substance is added, and iv) the apoptosis rate is measured, and to the substances which can be identified with the method.
    Type: Application
    Filed: February 20, 2009
    Publication date: June 25, 2009
    Applicant: CytoTools GmbH
    Inventors: Mark A. Freyberg, Peter Friedl, Dirk Kaiser
  • Anti-apoptotically active apatamers
    Publication number: 20070117768
    Abstract: The invention relates to anti-apoptotically active apatamers. The invention describes possible therapeutic and diagnostic applications for, among other things, treating arteriosclerosis, promoting the healing of wounds, treating AIDS, cancer, Alzheimer's disease, systemic lupus erythematosus as well a rheumatoid arthritis and other chronic inflammatory diseases.
    Type: Application
    Filed: December 10, 2004
    Publication date: May 24, 2007
    Applicant: CYTOTOOLS GMBH
    Inventors: Gerd Klock, Mark Freyberg, Dirk Kaiser
  • Dichloric acids, reactive chlorine compounds, their derivatives, anions and salts, as well as processes for their manufacture and use
    Publication number: 20070054959
    Abstract: This invention relates to aqueous solutions of reactive chlorine compounds having the empirical formulae H2Cl2O6 or ClO3H, for example, and the derivatives, anions or salts thereof. The invention further relates to methods for the production of said compounds and the use thereof in the pharmaceutical and particularly in the medical field, in cosmetics, medicinal care and in the domains of food technology and technology.
    Type: Application
    Filed: November 22, 2004
    Publication date: March 8, 2007
    Applicant: CYTOTOOLS GMBH
    Inventors: Klaus Wannowius, Dirk Kaiser
  • Method for identifying active anti-apoptosis compounds
    Publication number: 20060172921
    Abstract: The invention relates to a method for identifying substances with antiapoptotic activity, where i) cells which express both CD47 and the integrin ?v?3 are cultured, ii) the cells are caused to produce an apoptosis-inducing substance, and/or a substance or substances which induces/induce apoptosis is/are added, iii) the test substance is added, and iv) the apoptosis rate is measured, and to the substances which can be identified with the method.
    Type: Application
    Filed: January 6, 2006
    Publication date: August 3, 2006
    Applicant: CYTOTOOLS GMBH
    Inventors: Mark Freyberg, Peter Friedl, Dirk Kaiser
  • Method for identifying active anti apoptosis compounds
    Patent number: 7008773
    Abstract: The invention relates to a method for identifying substances with antiapoptotic activity, where i) cells which express both IAP and the integrin ?v?3 are cultured, ii) the cells are caused to produce an apoptosis-inducing substance, and/or a substance or substances which induces/induce apoptosis is/are added, iii) the test substance is added, and iv) the apoptosis rate is measured, and to the substances which can be identified with the method.
    Type: Grant
    Filed: November 2, 2000
    Date of Patent: March 7, 2006
    Assignee: CytoTools GmbH
    Inventors: Mark A. Freyberg, Peter Friedl, Dirk Kaiser