Abstract: The presence of A-protein in an abnormally large amount in a sample, such as blood, from an individual is diagnostic of primary or metastatic cancer in the individual. The presence of A-protein is most readily detected by immunological reaction of it with specific antibodies. A preferred procedure for detecting the presence of A-protein in samples is by a sandwich assay using two antibodies with different epitopic specificities for A-protein.
Type:
Grant
Filed:
December 18, 1997
Date of Patent:
February 13, 2001
Assignee:
Cytra Corporation
Inventors:
Geoffrey J. Schmidt, Kenneth L. Hoffman