Patents Assigned to Cyvax, Inc.
  • Publication number: 20180280490
    Abstract: Provided herein are methods, compositions, and kits for preventing, inhibiting, reducing the severity of, or treating a disease or condition. A pharmaceutical composition provided herein can comprise a nucleic acid sequence encoding an antigen fused to an immune cell product, e.g., MIP-3?, and an adjuvant. The antigen can be from a bacteria, virus, fungus, parasite, or cancer. The antigen can be an Alzheimer's disease antigen.
    Type: Application
    Filed: March 20, 2018
    Publication date: October 4, 2018
    Applicant: Cyvax, Inc.
    Inventor: Richard Markham
  • Publication number: 20180243388
    Abstract: Melanoma vaccines are provided. Compositions and methods are provided for making and using melanoma vaccine constructs, alone, or in combination with at least one adjuvant. Compositions and methods can be in combination with other therapeutic compositions. The melanoma vaccine constructs of DNA or protein.
    Type: Application
    Filed: November 12, 2015
    Publication date: August 30, 2018
    Applicant: Cyvax, Inc.
    Inventors: Richard Markham, James Gordy
  • Publication number: 20180161412
    Abstract: Protein-based vaccines against infectious agents, including malaria and Zika virus, are described. The protein-based vaccines include an antigen domain and an immature dendritic cell targeting domain and are administered in combination with an adjuvant.
    Type: Application
    Filed: December 14, 2017
    Publication date: June 14, 2018
    Applicant: Cyvax, Inc.
    Inventor: Richard Markham
  • Patent number: 9937248
    Abstract: Disclosed herein are DNA-based vaccines against amyloid ? peptide for use in treating and alleviating Alzheimer's Disease and related conditions. A DNA construct comprising DNA encoding one or more amyloid ? peptides, such as amino acids 1-11 of A?, and DNA encoding a hepatitis B antigens, is administered with an adjuvant or by electroporation. The vaccine can also be formulated using a fusion protein expressed by the disclosed DNA, in combination with an adjuvant.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: April 10, 2018
    Assignee: Cyvax, Inc.
    Inventor: Bira Arya
  • Patent number: 9433665
    Abstract: Disclosed herein are DNA-based vaccines against amyloid ? peptide for use in treating and alleviating Alzheimer's Disease and related conditions. A DNA construct comprising DNA encoding one or more amyloid ? peptides, such as amino acids 1-11 of A?, and DNA encoding a hepatitis B antigens, is administered with an adjuvant or by electroporation. The vaccine can also be formulated using a fusion protein expressed by the disclosed DNA, in combination with an adjuvant.
    Type: Grant
    Filed: January 10, 2014
    Date of Patent: September 6, 2016
    Assignee: Cyvax, Inc.
    Inventors: Bira Arya, Richard Markham
  • Publication number: 20140199338
    Abstract: Disclosed herein are DNA-based vaccines against amyloid ? peptide for use in treating and alleviating Alzheimer's Disease and related conditions. A DNA construct comprising DNA encoding one or more amyloid ? peptides, such as amino acids 1-11 of A?, and DNA encoding a hepatitis B antigens, is administered with an adjuvant or by electroporation. The vaccine can also be formulated using a fusion protein expressed by the disclosed DNA, in combination with an adjuvant.
    Type: Application
    Filed: January 10, 2014
    Publication date: July 17, 2014
    Applicant: Cyvax, Inc.
    Inventors: Bira Arya, Richard Markham
  • Publication number: 20140010837
    Abstract: Provided herein are methods, compositions, and kits for preventing, inhibiting, reducing the severity of, or treating a disease or condition. A pharmaceutical composition provided herein can comprise a nucleic acid sequence encoding an antigen fused to an immune cell product, e.g., MIP-3?, and an adjuvant. The antigen can be from a bacteria, virus, fungus, parasite, or cancer. The antigen can be an Alzheimer's disease antigen.
    Type: Application
    Filed: September 11, 2013
    Publication date: January 9, 2014
    Applicant: Cyvax, Inc.
    Inventor: RICHARD MARKHAM
  • Patent number: 8557248
    Abstract: Provided herein are methods, compositions, and kits for preventing, inhibiting, reducing the severity of, or treating a disease or condition. A pharmaceutical composition provided herein can comprise a nucleic acid sequence encoding an antigen fused to an immune cell product, e.g., MIP-3?, and an adjuvant. The antigen can be from a bacteria, virus, fungus, parasite, or cancer. The antigen can be an Alzheimer's disease antigen.
    Type: Grant
    Filed: August 9, 2011
    Date of Patent: October 15, 2013
    Assignee: Cyvax, Inc.
    Inventor: Richard Markham