Abstract: Disclosed is a method for producing a stage for amplifying the power of a variable envelope signal including at least one amplifier. For each amplifier, a form of ideal variation in average power POUTL is selected. For each value of each setting parameter and for each average input power value, a value of an optimisation criterion is calculated on the basis of the mathematical expectation of at least one optimisation parameter. An optimum value of each setting parameter is determined and the amplification stage is produced with a number of amplifiers in parallel determined on the basis of an average output power value and with, for each amplifier, matching circuits providing the optimum values of the setting parameters. The invention also relates to an amplification stage produced in this manner.

Abstract: Assemblies for storing, handling, transporting, viewing, evaluating, and/or shipping corneal tissue are provided. The assembly includes a corneal tissue carrier within a vial, the transport vial removably coupled to a stabilization base, wherein the ease of access to the graft carrier allows administering the corneal tissue sample to a patient in rapid succession so that more surgeries can be performed by a single surgeon in a single day.

Abstract: A water-in-oil personal care emulsion with water droplets size below 20 microns, the droplets containing solubilized cystine. A process of making an emulsion is also described.

Abstract: The invention provides compounds of formula (I): or pharmaceutically-acceptable salts thereof, that are inhibitors of Janus kinases and release an active metabolite in vivo. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat inflammatory skin diseases and other diseases.

Abstract: The invention relates to a shaped vegetarian meat product comprising: a) 30-80 wt. % water; b) 5-35 wt. % oil, said oil having a solid fat content at 20 degrees Celsius (N20) of at least 1.5%; c) 2-25 wt. % protein selected from algal protein, bacterial protein, dairy protein, egg protein, fungal protein, plant protein, and combinations thereof; d) 0-40 wt. % of one or more particulate ingredients selected from herbs, spices, vegetables and combinations thereof; wherein the vegetarian meat product contains at least 4 vol. % of oil droplets having an equivalent spherical diameter in the range of 100 micrometer to 1,000 micrometer as determined by means of micro computed tomography. This shaped vegetarian meat product has a very attractive juicy appearance and texture.

Abstract: Methods include inputting an array of pixels, where each pixel in the array of pixels has a pixel dose. The array of pixels represents dosage on a surface to be exposed with a plurality of patterns, each pattern of the plurality of patterns having an edge. A target bias is input. An edge of a pattern in the plurality of patterns is identified. For each pixel which is in a neighborhood of the identified edge, a calculated pixel dose is calculated such that the identified edge is relocated by the target bias. The array of pixels with the calculated pixel doses is output. Systems for performing the methods are also disclosed.

Abstract: The invention provides compounds of formula (I): or pharmaceutically-acceptable salts thereof, that are inhibitors of Janus kinases. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat inflammatory and autoimmune skin diseases.

Abstract: A system for supplying power to a portable battery pack including a battery enclosed by a wearable and replaceable pouch or skin using at least one solar panel is disclosed, wherein the pouch or skin can be provided in different colors and/or patterns. Further, the pouch or skin can be MOLLE-compatible. The battery comprises a battery element housed between a battery cover and a back plate, wherein the battery element, battery cover, and back plate have a slight curvature or contour. Further, the battery comprises flexible leads.

Abstract: The present invention relates to the general field of the treatment and prevention of diseases involving an inflammatory condition, namely sepsis or infectious or viral diseases as well as diseases requiring for the of treatment an immunosuppressive activity namely autoimmune diseases and graft rejection. In particular, the invention relates to an inhibitor of the activity or the formation of the PP1/GADD34 complex for the treatment of a condition requiring an immunosuppressive activity or an anti-inflammatory activity.

Abstract: The present disclosure provides methods of treating and/or preventing inflammatory bowel disease (IBD) and graft-versus-host disease (GVHD) using salt-inducible kinase (SIK) inhibitors, such as macrocyclic SIK inhibitors of Formula (I), imidazolyl SIK inhibitors of Formula (II), and urea and carbamate SIK inhibitors of Formula (III-A) (e.g., urea and carbamate STK inhibitors of Formula (III)).

Abstract: A mechanism for locking the heel portion of a snow glide board boot binding. The heel-locking device locks and unlocks by rotating a lever. The heel-locking device allows the rider to lock their boot binding hands-free to the snow glide board by pressuring the back of the boot binding baseplate with their boot while the heel-locking device is in the locked position. Once locked, the rider must rotate the lever to a predetermined position to unlock the boot binding.

Abstract: A cutting tool for cutting flexible building materials, such as, for example, rubber or vinyl baseboards, chair rails and crown molding, at an angle. The cutting tool includes a pair of risers moveably connected near a center of a base with a hinge connection. A blade holder and blade positioned between the risers and moveable from a starting position to a cutting position. The blade can be set to a range of angles relative to the base by rotating the risers and locking the risers in an angle relative to the base.

Abstract: An exhaust gas purification device for a vehicle comprises a coil configured to generate an electromagnetic field, a magnetic flux concentrator, surrounding the coil and configured to conduct the electromagnetic field generated by the coil, and an exhaust gas purification substrate. The exhaust gas purification substrate comprises an upstream segment having an upstream section, and a downstream segment having a downstream section. The exhaust gas purification substrate further comprises at least one intermediate segment between the upstream segment and the downstream segment, the intermediate segment having a central section smaller than the upstream section and/or the downstream section.

Abstract: The invention provides a sewing device which can precisely and evenly carry out a great variety of sewing works further with a good productivity. The sewing device has a sewing machine (2), and a dual-arm robot (7) having a first arm (5) and a second arm (6) which can operate an object to be sewn (4) supplied to a sewing motion portion (3) of the sewing machine. The duel-arm robot is provided with a camera which can image the sewing motion portion. Further, the sewing device is provided with an image processing portion which processes an image information acquired by the camera, and a command transmitting portion which transmits commands to an arm control portion controlling the first arm and the second arm on the basis of a processing result of the image processing portion.

Abstract: The invention discloses a separation matrix which comprises a plurality of separation ligands, defined by the formula R1-L1-N(R3)-L2-R, immobilized on a support, wherein R1 is a five- or six-membered, substituted or non-substituted ring structure or a hydroxyethyl or hydroxypropyl group; L1 is either a methylene group or a covalent bond; R2 is a five-or six-membered, substituted or non-substituted ring structure; L2 is either a methylene group or a covalent bond; R3 is a methyl group; and wherein if R1 is a hydroxyethyl group and L1 is a covalent bond, R2 is a substituted aromatic ring structure or a substituted or non-substituted aliphatic ring structure.

Abstract: A method for producing briquettes from pellet fines, DRI sludge, DRI fines and dust from DRI dedusting systems and, in this way, reincorporating same into steel production processes, thereby contributing to the re-use of the by-products of these processes, as well as minimizing the stocks of these types of materials and, consequently, helping to improve the environment. The invention comprises: grinding and sieving the pellet fines and the DRI sludge; sieving the DRI fines; storing the dust from DRI dedusting systems; briquetting with roller presses, using liquid sodium silicate and bentonite or composite Portland cement as binders; sieving the briquettes; shredding the edges and waste of the fresh briquettes; and curing in order to improve the physical properties thereof, such as strength. Once cured, the fresh briquette can be stored or sent directly to direct-reduced iron production processes for use as part of the feedstock for reduction ovens or reactors.

Abstract: A method for controlling the distribution of the RF magnetic field in a magnetic resonance imaging system, having steps of: placing a cage coil in a permanent magnet supplying a permanent magnetic field along a first axis, and supplying an RF signal to the cage coil in order for the coil to generate an RF magnetic field rotating in a plane that runs perpendicular to the first axis; and putting in place an electromagnetic resonator, the resonance mode of which is excited by the rotating magnetic field, the resonator being placed in a position inside or outside the cage coil and at a distance from a region to be analyzed of an object to be placed in the cage coil, the resonance mode and the position of the resonator in relation to the volumetric antenna being suitable for adjusting the intensity of the rotating magnetic field in an area of the region to be analyzed.

Abstract: A material for reducing the content of polluting and/or unwanted substances in a liquid includes at least one polymeric and/or inorganic base, suitable to be immersed in the liquid, having at least a surface, whereto is bonded at least one catalyst of the degradation reaction of inorganic salts in gaseous substances. The catalyst, whose function is to reduce the energy required for the activation of said reaction and to accelerate its progress, is an enzyme preferably selected among the lyase group, the hydrolase group and the oxidoreductase group.

Abstract: The present invention relates to a process for the preparation of amorphous Selexipag from Selexipag crystalline salts using a solvent.

Abstract: A method for producing an MRI image includes the steps of acquiring lines of a volume under analysis using a steady-state gradient echo sequence in successive repetition times (TR); and applying an inhomogeneous magnetization transfer (ihMT) pre-saturation module (TMT) in each repetition time. The duration of the repetition times is greater than 20 milliseconds.