Abstract: Method and apparatus for high-efficiency radio frequency (RF) power amplification. A method high-efficiency RF power amplification comprises receiving control and power signals, sampling power output of a main stage amplifier, comparing sampled amplifier output power with output power requirement information, reconfiguring bias of the cascaded amplifiers based on power adjustment information, coupling the output of a main stage power amplifier to a load mismatch protection circuit. An electronic apparatus for a Doherty-type high-efficiency RF power amplifying subsystem comprising a power interface circuit coupled to a bias network control circuit, an output power sampling circuit, the comparator comparing signal representing amplifier output power with the power control signal, the bias network control circuit adapts bias condition of the amplifier block, a load mismatch protection circuit provides well-controlled load, thereby the amplifier block amplifies RF input signal transmitted to the subsystem output.