Abstract: The present invention provides a method for producing fisetin or fisetin derivatives, which is capable of mass production. The method for producing fisetin or fisetin derivatives according to the present invention is capable of mass-producing fisetin or fisetin derivatives without a purification process such as a column chromatography process.
Type:
Grant
Filed:
January 7, 2022
Date of Patent:
February 28, 2023
Assignee:
DAEGU CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
Inventors:
Dong Wook Kang, Min Gi Chu, Seok Ju Lee, Eun Jung Lee
Abstract: A method for producing a bis(fluorosulfonyl)imide lithium salt is disclosed. The method includes the steps of: (a) reacting bis(chlorosulfonyl)imide with NH4F(HF)n (n=0-10) to prepare ammonium bis(fluorosulfonyl)imide; and (b) reacting the ammonium bis(fluorosulfonyl)imide with a lithium base, wherein in at least one of steps (a) and (b), after the reaction, a process of adding an alkoxy trialkyl silane to the reaction solution to remove a fluorine anion is performed.
Type:
Application
Filed:
September 4, 2019
Publication date:
November 11, 2021
Applicant:
DAEGU CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
Inventors:
Sang Ryul LEE, Kyoung Chol KIM, Ja Young PARK, Ji Hyeong KIM, Jeong In KIM, Seok Ju LEE, Jongyun JANG, Seongjeong LEE, Mingi CHU, Dong Wook KANG
Abstract: A pharmaceutical composition and a health functional food composition for preventing, treating, or improving muscular diseases have licorice extract or a fraction thereof, or a compound isolated therefrom or a pharmaceutically acceptable salt thereof, as an active ingredient. The licorice extract or a fraction thereof, the compound or salt thereof induce the myoblasts proliferation and promote the differentiation into myotubes, and since the licorice extract or a fraction thereof, the compound or salt thereof has an excellent effect on regenerating damaged muscles, various muscle diseases are effectively prevented, improved or treated using the composition.
Type:
Application
Filed:
June 17, 2020
Publication date:
October 14, 2021
Applicants:
RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY, KOREA INSTITUTE OF ORIENTAL MEDICINE, DAEGU CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
Inventors:
Inho CHOI, Eun Ju LEE, So-young PARK, Yong-Ho LEE, Jin Yeul MA, Won-Kyung CHO, Hye Jin YANG
Abstract: An anticancer composition includes cervical cancer-derived autocrine motility factor (AMF) as an effective component. The cervical cancer-derived AMF has an excellent effect of inhibiting the proliferation of liver cancer, pancreatic cancer, breast cancer, lung cancer, prostate cancer, and colon cancer, and inducing cell death. The composition can be used as an anticancer therapeutic agent.
Type:
Grant
Filed:
June 4, 2018
Date of Patent:
September 21, 2021
Assignee:
DAEGU CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION