Abstract: Peptides are easy to pass through a tissue-blood barrier, have excellent physiological activity in the protective activity of cells, and have an economic advantage due to low production costs. In addition, since there is no side effect of cell proliferation, a pharmaceutical composition containing a peptide of an aspect as an active ingredient can be usefully used in the treatment or prevention of neurological disorders and degenerative brain diseases.

Abstract: An electrode catalyst is configured such that non-noble metal particles, noble metal particles or nitride-doped noble metal particles are supported on a carbon support, wherein the carbon support has a 2D planar crystal structure or a 3D polyhedral crystal structure and is doped with nitrogen, thereby exhibiting increased catalytic activity.

Abstract: A three-dimensional electrode device and a method for manufacturing the same are disclosed. A three-dimensional electrode device as disclosed can be in close contact with target cells in a retina without damaging the retina to apply electrical stimulation to the retina. The three-dimensional electrode device can include a board prepared to be inserted into a photoreceptor layer in an eyeball and formed of a transparent material; and a plurality of electrodes formed on the board and configured to stimulate a retina. The board can be prepared to be deformed corresponding to a shape of the retina and configured to make the electrodes be in close contact with the retina.

Abstract: A graph upscaling method and apparatus is disclosed. The graph upscaling apparatus may store, in a main memory, original graph data including topological data including a vertex and an edge, determine a parent edge using a hash function and the original graph data, and generate a new edge based on the determined parent edge. The graph upscaling apparatus may store, in a main memory, original graph data including topological data including a vertex and an edge, allocate identities (IDs) of edges to be generated to cores included in a central processing unit (CPU) based on the number of the cores, and generate new edges based on the IDs of the edges using a hash function and the original graph data.

Abstract: A physical stability determination system includes a wearable device configured to collect sleep information, activity information and heartbeat information of a user, a data preprocessor configured to divide each of the activity information and the heartbeat information into data of a sleep area and data of an activity area, based on the sleep information, and a data processor configured to calculate a sleep state, an activity intensity or a heartbeat state of the user from the data of the sleep area and the data of the activity area. The data of the sleep area may be used to calculate the sleep state in the data processor, and the data of the activity area may be used to calculate the activity intensity or the heartbeat state in the data processor.

Abstract: An apparatus and method for determining bio-information of a target using an impulse radar are provided. The method may include generating a frame set by accumulating frames received at preset time intervals, determining a first magnitude spectrum of the frame set corresponding to a first frequency axis by performing a frequency conversion of frames included in the frame set in a sampler index axis direction, determining a second magnitude spectrum of the frame set corresponding to the first frequency axis and a second frequency axis by performing a frequency conversion of the first magnitude spectrum in a time axis direction, determining a third magnitude spectrum of the frame set by adding up values of the second magnitude spectrum for each second frequency, and determining a frequency indicating a peak in the third magnitude spectrum as a heartbeat frequency of the target.

Abstract: Provided is a method and apparatus for assisting spasticity and clonus evaluation using an inertia sensor, the apparatus including an acquirer configured to acquire a measured value from an inertia sensor attached to an object, a calculator configured to calculate an angle of a joint of the object based on the measured value, and a processor configured to evaluate a spasticity and a clonus based on the angle of the joint.

Abstract: The present invention provides a selective bonding method of polymer substrates. The present invention allows selective interfacial bonding between a polymer substrate and a parylene layer by using a mask pattern and plasma treatment, and enables the formation of a three-dimensional structure by injecting a fluid into a non-bonded area.

Abstract: A relational database storage method according to one embodiment generates a join graph including tables and edges based on either a database schema including referential constraints among database tables or a query workload containing a set of join predicates, classifies the type of tables based on the cost of a join operation between the tables included in the join graph, classifies the type of edges in the join graph on the basis of the type of the tables connected to each other by the edge, adds a virtual edge between two tables satisfying the indirect join condition, and generates a database partitioning scheme for the join graph based on the set of tables in the join graph and their type, the set of edges in the join graph and their type, and virtual edges.

Abstract: Disclosed herein is modeling method which is enabled to analyses neurons in order to reduce real neurons physiologically properly using the relationship between asymmetry in signal propagation between a soma and dendrites and dendritic excitability. The modeling method for neurons include determining voltage attenuation factors which represent properties of signal propagation between dendrites and a soma and is represented as functions of distance from the soma; and determining a plurality of passive parameter at a pre-determined path length using system parameters defined from the anatomical model comprising the voltage attenuation factors at the pre-determined path length.

Abstract: Provided is a collimator including a base unit configured to form a radiation path of light; a pair of first moving members rotatably installed in the base unit; a pair of second moving members movably installed in the base unit; and an actuator configured to externally receive power and transmit the power to the first moving members and the second moving members, wherein a first space may be formed between the first moving members, a second space may be formed between the second moving members, and the light may pass through a radiation area corresponding to an overlapping area of the first space and the second space.

Abstract: Disclosed is a method of removing motion artifacts from functional near-infrared spectroscopy (fNIRS) signals. The method includes: disposing N optodes at a plurality of locations on a scalp, and forming a plurality of channels between the N optodes; calculating a correlation coefficient difference index of a neighbor channel around each receiver optode, and detecting a receiver optode in which a motion artifact has occurred based on the correlation coefficient difference index; and removing motion artifacts based on the detected receiver optode and an arrangement structure of the N optodes.

Abstract: A method for designing all coverage of valid primer pairs, which satisfy various filtering constraints provided by users with respect to a given sequence database and has validated specificity to given sequences, is provided. By screening all suitable primer pairs present on a given DNA sequence database without omitting any one primer pair and also screening all primers having a coverage of 1 or more as well as primers having a coverage of 1, a user can be allowed to give rankings to the primers in order to easily select the primers having a high success rate in biological experiments from the resulting primers.

Abstract: A matrix data processing method performed by a computing device which performs a matrix multiplication operation includes, with respect to each of one or more elements included in a matrix, when a value of each element satisfies a designated condition, determining the element to be a don't-care element and determining an output value of the don't-care element, generating a bitstream based on the output value of the don't-care element and index values of valid elements included in the matrix, and equally dividing the bitstream into pieces of a designated number, and generating a Huffman code corresponding to each of a plurality of lower bitstreams that are generated as a result of the equal division.

Abstract: The present disclosure relates to measuring biosignals (particularly, electroencephalogram) of fish in a non-invasive and multi-channels manner, with a multi-channel electrode array of one or more conductive plates non-invasively attached to the epidermis of the fish outside of the water a; a reference electrode non-invasively attached to the epidermis of the fish outside of the surface of the water; a supply device that supplies a predetermined material and oxygen to the fish outside of the water; and a minute tube inserted into the oral cavity of the fish outside of the water to resuscitate the fish in a stable state to generate normal electroencephalogram.

Abstract: The present invention relates to a soft actuator moving linearly against external stimuli whose expansion and contraction can be actively controlled, suggesting that the actuator of the invention overcomes the problems of the conventional soft actuators, The soft actuator of the present invention can be repetitively driven quickly and accurately by controlling heating and cooling by using thermoelectric effect and, the soft actuator of the present invention can realize bending, tensioning, compression, and rotational driving of a tubular device containing a driver.

Abstract: Disclosed herein is a method of manufacturing an artificial synapse device, which includes forming a first electrode on a substrate, forming a first resistance change layer on the first electrode, and forming an iridium (Ir) electrode on the first resistance change layer. In the case where an artificial synapse device is manufactured by the method of manufacturing an artificial synapse device, it is possible to enhance the reliability of the artificial synapse device by reducing the resistance distribution of the artificial synapse device manufactured by forming oxygen vacancies instead of filaments.

Abstract: Provided is a centrifugal valve control apparatus including: a body part including a body having a chamber and a channel connected to the chamber, and a valve configured to open and close the channel; a heating part coupled to the body and including a heating member disposed at a position corresponding to the valve; and a rotation driving part configured to rotate the body part and the heating part together, wherein the valve is formed to open and close the channel by the heating member while the body part and the heating part rotate together. Accordingly, the valve of the centrifugal valve control apparatus may be accurately controlled.

Abstract: Disclosed herein is a denoising device including a deriving part configured to, when corrupted noise data corrupted due to noises is received from source data, derive an estimated loss which is estimated when each symbol within noise data is reconstructed to the source data based on a predefined noise occurrence probability, a processor to process training of a defined learning model by including parameters related with the reconstruction of the source data from the noise data based on context composed of a sequence of neighbored symbols based on each symbol within the noise data and pseudo-training data using the estimated loss corresponding to the context, and an output part to output reconstructed data in which each symbol within the noise data is reconstructed to a symbol of the source data through a denoiser formed based on a result of the training processing.